Persistent opioid use and socio-economic factors: a population-based study in Norway.


BACKGROUND:A growing proportion of the population is using opioids for longer time periods, but little is known about the characteristics of patients who are persistent opioid users. We therefore studied the association between socio-economic factors and persistent vs. short-term opioid use 4 years later. METHODS:The background population is the complete Norwegian population in 2001. The study population is derived from two groups aged 35 years or older in 2001 who met one of the following criteria in 2005: (1) persistent opioid users (n = 15,113) or (2) short-term opioid users (n = 214,061). The applied definition of persistent opioid use corresponds to an average daily dose indicating likely daily use of opioids during 365 consecutive days. The socio-economic factors work status, income, marital status, immigrant status and education were obtained from the Population and Housing Census of 2001, and data on opioid use in 2005 were obtained from the complete national Norwegian Prescription Database. For logistic regression analyses, the study population was stratified by gender and by age over/under 67 years. RESULTS:In the 35- to 67-year-old age group, receiving a disability pension was more common in persistent opioid users compared with short-term opioid users (48% vs. 16% for women, 36% vs. 9% for men). Adjusted odds ratios for receiving a disability pension were 6.51 and 5.77 for women and men, respectively. Being divorced/separated was associated with being a persistent opioid user (odds ratio of 1.4 for both genders). There were also negative associations between persistent opioid use and attained education level, an unemployed working status and income status. CONCLUSION:Disability pension, not working, divorce, low income and low education in 2001 were associated with persistent opioid use in 2005.


Svendsen K,Fredheim OM,Romundstad P,Borchgrevink PC,Skurtveit S




Has Abstract


2014-04-01 00:00:00












  • Danish Anaesthesia Allergy Centre - preliminary results.

    abstract:BACKGROUND:Anaphylactoid reactions in anaesthesia are rare and should ideally be investigated in specialist centres. At Gentofte University Hospital, we established such a centre in 1998 as a joint venture between the Departments of Anaesthesiology and Dermatology. We present the methodology, diagnostic algorithm and p...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Garvey LH,Roed-Petersen J,Menné T,Husum B

    更新日期:2001-11-01 00:00:00

  • Comparison of three doses of epidural fentanyl followed by bupivacaine and fentanyl for labor analgesia.

    abstract:BACKGROUND:Epidural fentanyl 100 microg after lidocaine-epinephrine test dose has been shown to provide adequate analgesia in early labor. This investigation determines the effect of three different bolus doses of epidural fentanyl on duration and quality of analgesia during early first stage of labor. METHODS:In this...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章,随机对照试验


    authors: Siddik-Sayyid SM,Taha SK,Azar MS,Hakki MA,Yaman RA,Baraka AS,Aouad MT

    更新日期:2008-10-01 00:00:00

  • Haemodynamic stability after paracervical block: A randomized, controlled, double-blind study comparing bupivacaine-adrenaline with bupivacaine.

    abstract:BACKGROUND:Paracervical block is widely used in gynaecological interventions on cervix and uterus. Many surgeons add adrenaline 100 μg or pitressin 3-5 IU in a total volume of 10-20 mL to reduce total blood loss. We wanted to examine haemodynamic stability in healthy patients given bupivacaine with and without adrenali...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章,随机对照试验


    authors: Sjoeen GH,Falk RS,Hauge TH,Langesaeter E

    更新日期:2019-03-01 00:00:00

  • Inhaled prostacyclin for the prevention of increased pulmonary vascular resistance in cemented hip hemiarthroplasty-A randomised trial.

    abstract:BACKGROUND:Bone cementation may cause pulmonary vasoconstriction and ventilation/perfusion abnormalities in patients undergoing cemented hip hemiarthroplasty. In this randomised trial, we tested the hypothesis that intra-operative inhalation of prostacyclin could attenuate the increase in pulmonary vascular resistance ...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章,随机对照试验


    authors: Hård Af Segerstad M,Olsen F,Houltz E,Nellgård B,Ricksten SE

    更新日期:2019-10-01 00:00:00

  • Sublingual buprenorphine for premedication and postoperative pain relief in orthopaedic surgery.

    abstract::The effect of sublingual buprenorphine (Temgesic) as a premedicant and for postoperative pain relief compared with morphine/pethidine was studied in 50 patients scheduled for elective surgery of the knee joint. Twenty-five patients received buprenorphine 0.4 mg sublingually 1 h before surgery and the same dose on dema...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Risbo A,Chraemmer Jørgensen B,Kolby P,Pedersen J,Schmidt JF

    更新日期:1985-02-01 00:00:00

  • Prediction of post-operative pain by an electrical pain stimulus.

    abstract:BACKGROUND:Treatment of post-operative pain is still a significant problem. Recently, interest has focused on pre-operative identification of patients who may experience severe post-operative pain in order to offer a more aggressive analgesic treatment. The nociceptive stimulation methods have included heat injury and ...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Nielsen PR,Nørgaard L,Rasmussen LS,Kehlet H

    更新日期:2007-05-01 00:00:00

  • Methylprednisolone intravenously 1 day after surgery has sustained analgesic and opioid-sparing effects.

    abstract:BACKGROUND:In previous studies on glucocorticoids for postoperative pain, the test drug has been given perioperatively, usually before measurement of baseline pain. In order to evaluate the time course and magnitude of the analgesic effect of a glucocorticoid in well-established postoperative pain, we compared methylpr...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Romundstad L,Breivik H,Niemi G,Helle A,Stubhaug A

    更新日期:2004-11-01 00:00:00

  • Analysis of left ventricular systolic function during elevated external cardiac pressures: an examination of measured transmural left ventricular pressure during pressure-volume analysis.

    abstract:BACKGROUND:Variations or disturbances in intrathoracic and extracardiac pressures (ECP) occur in critically ill and anaesthetised patients. There are uncertainties concerning the analysis of left ventricular pressure-volume relationship (LVPVR) and the calculation of systolic function parameters when conducted without ...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Haney MF,Johansson G,Häggmark S,Biber B

    更新日期:2001-08-01 00:00:00

  • Reduced right ventricular diameter during cardiac arrest caused by tension pneumothorax - a porcine ultrasound study.

    abstract:INTRODUCTION:Advanced life support (ALS) guidelines recommend ultrasound to identify reversible causes of cardiac arrest. Right ventricular (RV) dilatation during cardiac arrest is commonly interpreted as a sign of pulmonary embolism. The RV is thus a focus of clinical ultrasound examination. Importantly, in animal stu...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Caap P,Aagaard R,Sloth E,Løfgren B,Granfeldt A

    更新日期:2017-08-01 00:00:00

  • Comparison of a propofol target-controlled infusion and inhalational sevoflurane for fibreoptic intubation under spontaneous ventilation.

    abstract:BACKGROUND:A propofol target-controlled infusion (TCI) is often proposed for the management of difficult airway intubation and fibreoptic intubation under anaesthesia and spontaneous ventilation. No data are available about sevoflurane. The aim of the present study was to compare propofol and sevoflurane as hypnotics d...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章,随机对照试验


    authors: Bonnin M,Therre P,Albuisson E,Beaujard H,Barthelemy I,Mondie JM,Bazin JE

    更新日期:2007-01-01 00:00:00

  • Assessment of acute stroke cerebral CT examinations by anaesthesiologists.

    abstract:BACKGROUND AND PURPOSE:It is essential to diagnose ischaemic stroke as soon as possible after symptom onset, so that thrombolytic treatment can be initiated as quickly as possible. This might be greatly facilitated if cerebral CT could be carried out in a pre-hospital setting. The aim of this study was to evaluate if a...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Hov MR,Nome T,Zakariassen E,Russell D,Røislien J,Lossius HM,Lund CG

    更新日期:2015-10-01 00:00:00

  • Clinical effects of regional intravenous guanethidine (Ismelin) in reflex sympathetic dystrophy.

    abstract::Twenty patients with documented reflex sympathetic dystrophy were treated with a series of regional intravenous guanethidine blocks. The mean delay between the first clinical symptoms and the start of guanethidine blocks was 3.6 months. The overall result was good in 11 patients, moderate in two patients and poor in s...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Driessen JJ,van der Werken C,Nicolai JP,Crul JF

    更新日期:1983-12-01 00:00:00

  • Effects of thoracic epidural block and the beta-1-adrenoreceptor agonist prenalterol on the cardiovascular response to infrarenal aortic cross-clamping in man.

    abstract::Sixteen patients scheduled for abdominal aortic resection and grafting were randomly assigned to two groups to study the cardiovascular effects of infrarenal aortic cross-clamping. The patients in the first group had received a thoracic epidural block followed by intravenous administration of the selective beta-1-adre...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Reiz S,Nath S,Pontén E,Friedman A,Bäcklund U,Olsson B,Rais O

    更新日期:1979-10-01 00:00:00

  • Improved long-lasting postoperative analgesia, recovery function and patient satisfaction after inguinal hernia repair with inguinal field block compared with general anesthesia.

    abstract:BACKGROUND:Inguinal hernia repair is a common surgical procedure, and different types of anesthetic techniques are in use. We wanted to test if preoperative inguinal field block (IFB) with ropivacaine would provide benefits in the postoperative period compared with general anesthesia and wound infiltration. METHODS:Si...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Aasbø V,Thuen A,Raeder J

    更新日期:2002-07-01 00:00:00

  • Anesthetic effect of epidural anesthesia with cephalad or caudad catheterization for ankle surgery or hemorrhoidectomy.

    abstract:BACKGROUND:The larger size of the first sacral nerve root has been reported to be an unfavorable factor leading to sacral sparing in epidural anesthesia. Previous studies have shown that an adequate analgesic effect of the epidural block was achieved with the catheter placement in the caudal direction. In this study, t...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Chou WY,Hsu CJ,Cheng JT,Yang LC,Lin CR,Chia YY,Yu SW,Tan PH

    更新日期:2005-03-01 00:00:00

  • Preferences for shared decision making in chronic pain patients compared with patients during a premedication visit.

    abstract:BACKGROUND:There is some evidence that patients' outcomes improve if they are involved in shared decision making (SDM). A chronic pain clinic or premedication visit could be adequate settings for the implementation of SDM. So far, the patients' preference for involvement in decision making and their desire for informat...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Spies CD,Schulz CM,Weiss-Gerlach E,Neuner B,Neumann T,von Dossow V,Schenk M,Wernecke KD,Elwyn G

    更新日期:2006-09-01 00:00:00

  • Repeated episodes of myocardial ischaemia during combined thoracic epidural-isoflurane anaesthesia.

    abstract::A patient with a history of coronary artery diseases developed new ST segment depressions in the ECG registration during a low dose (0.7%) isoflurane anaesthesia that was combined with a continuous thoracic epidural analgesia. Simultaneously a small decrease in mean arterial blood pressure (MAP) was noted. During the ...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Sigurdsson GH,Brouwer RP,Thomson D

    更新日期:1994-07-01 00:00:00

  • Recovery characteristics of sevoflurane or halothane for day-case anaesthesia in children aged 1-3 years.

    abstract:BACKGROUND:Our objective was to compare the recovery characteristics of sevoflurane and halothane for short day-case anaesthesia in a specifically limited age group of children 1-3 yr. METHODS:Eighty unpremedicated children undergoing day-case adenoidectomy were randomly assigned to receive inhalational induction with...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Viitanen H,Baer G,Annila P

    更新日期:2000-01-01 00:00:00

  • The effect of thoracic epidural analgesia on respiratory function after cholecystectomy.

    abstract::To assess the effect of thoracic epidural analgesia (TEA) on postoperative respiratory function and pulmonary complications, a prospective randomized trial was conducted in patients undergoing cholecystectomy. One hundred patients were allocated to TEA (n = 30), TEA + general anesthesia (TEA + GA) (n = 30), or general...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Hendolin H,Lahtinen J,Länsimies E,Tuppurainen T,Partanen K

    更新日期:1987-10-01 00:00:00

  • Propofol induces bronchodilation in mechanically ventilated chronic obstructive pulmonary disease (COPD) patients.

    abstract::The aim of this study was to evaluate the effects of propofol administration (2 i.v.) on the airways resistances and respiratory mechanics of patients affected by COPD exacerbation, requiring mechanical ventilation. Twenty patients required anaesthesia for diagnostic or therapeutic procedures. Fourteen consecu...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Conti G,Dell'Utri D,Vilardi V,De Blasi RA,Pelaia P,Antonelli M,Bufi M,Rosa G,Gasparetto A

    更新日期:1993-01-01 00:00:00

  • Dixyrazine for the prevention of postoperative nausea and vomiting after laparoscopic cholecystectomy.

    abstract:BACKGROUND:The study assessed the efficacy and safety of dixyrazine, an alternative neuroleptic drug to droperidol, in the prophylaxis of postoperative nausea and vomiting (PONV). METHODS:A total of 197 patients scheduled for laparoscopic cholecystectomy under general anesthesia were randomized to receive either dixyr...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Glaser C,Sitzwohl C,Wallner T,Lerche A,Marhofer P,Schindler I

    更新日期:2004-11-01 00:00:00

  • Modified natural and synthetically reconstituted surfactant therapies for acute lung injury caused by endotoxin in rats.

    abstract:BACKGROUND:Impairment of surfactant is involved in development of acute respiratory distress syndrome. To develop artificial surfactant substitute for clinical use, we prepared synthetically reconstituted surfactant (SRS) by adding porcine surfactant-associated protein B and C (SP-B and SP-C) to synthetic phospholipids...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Tashiro K,Nishizuka K,Matsumoto Y,Ohta K,Suzuki Y,Kobayashi T

    更新日期:1999-09-01 00:00:00

  • Effect of hemodiafiltration and sepsis on chemotaxis of granulocytes and the release of IL-8 and IL-10.

    abstract:BACKGROUND:Extracorporeal circulation, such as cardiopulmonary bypass and hemodialysis, has been associated with an activation of the immune system. Continuous veno venous hemodiafiltration (CVVHD) is used in critically ill septic patients. During CVVHD, cytokines are excreted in ultrafiltrate. When the membranes, used...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Toft P,Brix-Christensen V,Baech J,Krog J,Jørgensen HS,Tønnesen E,Petersen TK,Dagnaes-Hansen F

    更新日期:2002-02-01 00:00:00

  • Cervical epidural steroid injection for cervicobrachialgia.

    abstract::Fifty patients with chronic resistant cervicobrachialgia were randomly divided into two groups. Twenty-five patients (group A) were treated with cervical epidural steroid/lidocaine injections and 17 patients (group B) were treated with steroid/lidocaine injections into the posterior neck muscles. Another eight patient...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Stav A,Ovadia L,Sternberg A,Kaadan M,Weksler N

    更新日期:1993-08-01 00:00:00

  • High-frequency oscillatory ventilation combined with intermittent mandatory ventilation in critically ill neonates and infants.

    abstract::We have evaluated the high-frequency oscillatory ventilation (HFOV) combined with intermittent mandatory ventilation (IMV) in critically ill neonates and infants using the Babylog 8000 SW 4.0. We used HFOV combined with IMV as a rescue mode in 10 neonates and infants aged 1 day to 17 months, who were receiving maximal...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Murthy BV,Petros AJ

    更新日期:1996-07-01 00:00:00

  • Socioeconomic status and risk of intensive care unit admission with sepsis.

    abstract:BACKGROUND:A recent study showed higher risk of bacteremia among individuals with low socioeconomic status (SES). We hypothesized that patients with a low SES have a higher risk of intensive care unit (ICU) admission with sepsis compared to patients with higher SES. METHODS:This was a case-control study on patients wi...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Storm L,Schnegelsberg A,Mackenhauer J,Andersen LW,Jessen MK,Kirkegaard H

    更新日期:2018-08-01 00:00:00

  • Effects of age on minimum effective volume of local anesthetic for ultrasound-guided supraclavicular brachial plexus block.

    abstract:BACKGROUND:Involutional changes of peripheral nervous system occur with aging. The aim of the study was to determine the minimum effective volume of local anesthetic required to offer an effective ultrasound-guided supraclavicular brachial plexus block in 50% of middle-aged (< 50 years) and elderly (> 65 years) patient...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章


    authors: Pavičić Šarić J,Vidjak V,Tomulić K,Zenko J

    更新日期:2013-07-01 00:00:00

  • The rare Arg181Cys mutation in the μ opioid receptor can abolish opioid responses.

    abstract:BACKGROUND:Genetic variability contributes to variable clinical response to opioids. This study emerged from the observation of three Norwegian patients who showed no or extraordinary poor response to very high doses of opioids. We suspected a genetic defect and applied a 'most likely candidate gene' approach to invest...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Skorpen F,von Hofacker S,Bjørngaard M,Skogholt AH,Dale O,Kaasa S,Klepstad P

    更新日期:2016-09-01 00:00:00

  • Evaluation of the time course of action of maintenance doses of rocuronium (ORG 9426) under halothane anaesthesia.

    abstract::The time course of action of rocuronium was compared using three different sizes of maintenance doses after at least three subsequent administrations of the same repeat dose in each patients under halothane anaesthesia. Following endotracheal intubation facilitated with 0.6 rocuronium (ORG 9426), muscle relaxa...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Khuenl-Brady KS,Pühringer F,Koller J,Mitterschiffthaler G

    更新日期:1993-02-01 00:00:00

  • Can the "sympatho-galvanic reflex" (skin conductance response) be used to evaluate the extent of sympathetic block in spinal analgesia?

    abstract::The skin conductance response (SCR) (the "sympatho-galvanic reflex") was studied in volunteers and in a few patients undergoing spinal analgesia. Electrical stimulation over the clavicle, breath-holding during inspiration, a short, deep breath and a sharp sound provoked a marked change in conductance not only in the h...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Löfström JB,Malmqvist LA,Bengtsson M

    更新日期:1984-10-01 00:00:00