Fluorimetric quantification of brimonidine tartrate in eye drops.

abstract：:Alpinia officinarum is a rhizome belonging to the family zingeberaeceae. Hydro alcoholic extract by hot and cold maceration and methanol extract by percolation process Qualitative phytochemical analysis of extract of Alpinia officinarum rhizome showed a majority of the compound including tannins, alkaloids, flavonoids...

journal_title：Indian journal of pharmaceutical sciences

authors： Srividya AR,Dhanabal SP,Misra VK,Suja G

更新日期：2010-01-01 00:00:00

abstract：:A novel, simple, sensitive and rapid spectrophotometric method has been developed for simultaneous estimation of esomeprazole and domperidone. The method involved solving simultaneous equations based on measurement of absorbance at two wavelengths, 301 nm and 284 nm, lambda max of esomeprazole and domperidone respecti...

journal_title：Indian journal of pharmaceutical sciences

authors： Prabu SL,Shirwaikar A,Shirwaikar A,Kumar CD,Joseph A,Kumar R

更新日期：2008-01-01 00:00:00

abstract：:The objective of this work was to increase the amount of acyclovir in the basal epidermis, site of herpes virus simplex infection, using the solid lipid nanoparticles loaded gel cream as carriers. Solid lipid nanoparticles were prepared by high pressure homogenisation method and incorporated in a semisolid submicron g...

journal_title：Indian journal of pharmaceutical sciences

authors： Gide PS,Gidwani SK,Kothule KU

更新日期：2013-03-01 00:00:00

abstract：:Ivermectin, chloramphenicol, ampicillin and tetracycline HCl are common drugs in human and veterinary practice. The purpose of this study is to investigate the possible binding interactions between ivermectin and the antibiotics chloramphenicol, ampicillin and tetracycline HCl. Isothermal titration calorimetry was use...

journal_title：Indian journal of pharmaceutical sciences

authors： Kandeel M,Elgazar W,Kitade Y

更新日期：2012-11-01 00:00:00

abstract：:A simple, rapid, reliable, robust and optimized reversed phase high performance liquid chromatographic method for simultaneous estimation of doxycycline hyclate and curcumin was successfully developed and validated as per International Conference on Harmonization guidelines. The objective was achieved in terms of well...

journal_title：Indian journal of pharmaceutical sciences

authors： Dhal C,Ahmad FJ,Chauhan A,Jyothi M,Singh RM,Saini PK,Mathur SC,Singh GN

更新日期：2015-11-01 00:00:00

abstract：:This study aims at the isolation of filamentous fungi, extraction of metabolites, and evaluation of the cytotoxic properties on HeLa cells and normal human lymphocytes. We isolated fungi from the soil by serial dilution method. One of the isolates was chosen and identified as Aspergillus ochraceus Wilhelm (Trichocomac...

journal_title：Indian journal of pharmaceutical sciences

authors： Nadumane VK,Venkat P,Pal A,Dharod H,Shukla M,Prashanthi K

更新日期：2013-09-01 00:00:00

abstract：:The present study evaluated the in vitro antioxidant potential of different parts of Oroxylum indicum. 2,2-diphelyl 1-picrylhydrazyl (DPPH), nitric oxide, superoxide anion and hydroxyl radical scavenging potential and reductive ability assay of methanol extract of different parts i.e. root, root bark, stem, stem bark,...

journal_title：Indian journal of pharmaceutical sciences

authors： Mishra SL,Sinhamahapatra PK,Nayak A,Das R,Sannigrahi S

更新日期：2010-03-01 00:00:00

abstract：:A simple, reproducible and efficient reverse phase high performance liquid chromatographic method was developed for simultaneous determination of valsartan and hydrochlorothiazide in tablets. A column having 200 x 4.6 mm i.d. in isocratic mode with mobile phase containing methanol:acetonitrile:water:isopropylalcohol (...

journal_title：Indian journal of pharmaceutical sciences

authors： Tian DF,Tian XL,Tian T,Wang ZY,Mo FK

更新日期：2008-05-01 00:00:00

abstract：:A series of novel N-Sulphonamidomethyl piperzinyl fluoroquinolones were synthesized and screened antiviral activity. Eight compounds were synthesized through modifying the N(4)-hydrogen of piperazine in fluoroquinolones with formaldehyde and sulphanomides by Mannich reactions. The structures of the synthesized compoun...

journal_title：Indian journal of pharmaceutical sciences

authors： Selvam P,Rathore P,Karthikumar S,Velkumar K,Palanisamy P,Vijayalakhsmi S,Witvrouw M

更新日期：2009-07-01 00:00:00

abstract：:Recent studies have shown that gallic acid and its alkylesters induce apoptosis in different cell lines. Since new compounds with biological activity and less cytotoxicity to normal cells are necessary for cancer therapy, the aim of this study was to evaluate the cytotoxic effect of 1-(3,4,5-trihydroxyphenyl)-dodecylb...

journal_title：Indian journal of pharmaceutical sciences

authors： Maioral MF,Bubniak LD,Marzarotto MA,De Moraes AC,Leal P,Nunes R,Yunes RA,Santos-Silva MC

更新日期：2016-01-01 00:00:00

abstract：:The genome of rabies virus encodes five proteins; the nucleoprotein, the phosphoprotein, the matrix protein, the glycoprotein, and the RNA-dependent RNA polymerase. Among these, the glycoprotein is the most important as it is the major contributor to pathogenicity and virus neutralizing antibody response. Keeping in m...

journal_title：Indian journal of pharmaceutical sciences

authors： Tomar NR,Singh V,Marla SS,Chandra R,Kumar R,Kumar A

更新日期：2010-07-01 00:00:00

abstract：:A novel reversed-phase HPLC method has been developed and validated for the simultaneous determination of 2-phenoxyethanol, methylparaben, ethylparaben and propylparaben preservatives. The method uses a Lichrosorb C8 (150×4.6 mm, 5 µm) column and isocratic elution. The mobile phase consisted of a mixture of acetonitri...

journal_title：Indian journal of pharmaceutical sciences

authors： Shabir GA

更新日期：2010-07-01 00:00:00

abstract：:A simple, precise, accurate and rapid high performance thin layer chromatographic method has been developed and validated for the estimation of tenoxicam in the microemulsion gels. Tenoxicam was chromatographed on silica gel 60 F(254) TLC plate, as a stationary phase. The mobile phase was toluene: ethyl acetate: formi...

journal_title：Indian journal of pharmaceutical sciences

authors： Chandel S,Barhate CR,Srivastava AR,Kulkarni SR,Kapadia CJ

更新日期：2012-01-01 00:00:00

abstract：:This study was designed to evaluate the neuroprotective activity of ethanol extract of Pongamia pinnata stem bark in monosodium glutamate-induced neurotoxicity in rats. Neurotoxicity was induced by intraperitoneal injection of monosodium glutamate 2 g per kg body weight daily for 7 days. Ethanol extract of Pongamia pi...

journal_title：Indian journal of pharmaceutical sciences

authors： Swamy AH,Patel NL,Gadad PC,Koti BC,Patel UM,Thippeswamy AH,Manjula DV

更新日期：2013-11-01 00:00:00

abstract：:A simple, rapid, specific and sensitive liquid chromatography tandem mass spectrometric method has been developed and validated for the determination of doxycycline from the human plasma. Doxycycline is extracted from human plasma by solid phase extraction. Demeclocycline was used as an internal standard. Detection wa...

journal_title：Indian journal of pharmaceutical sciences

authors： Krishna AC,Sathiyaraj M,Saravanan RS,Chelladurai R,Vignesh R

更新日期：2012-11-01 00:00:00

abstract：:In this paper we report the synthesis of a new family of 4-alkyl isocoumarin derivatives having bromo carbonyl and amino carbonyl group at 3(rd) position of the heterocyclic ring. Synthesis, spectral analysis and bioactivity of new isocoumarin derivatives are discussed in this paper. Some of the synthesized compounds ...

journal_title：Indian journal of pharmaceutical sciences

authors： Yadav P,Purohit NV

更新日期：2011-03-01 00:00:00

abstract：:Mitochondrial sodium calcium exchange inhibitors are novel agents in the treatment of type-II diabetes due to their glucose dependent efficacy. While the compounds of this class are expected to correct hyperglycemia, they do not lower basal blood glucose level, thus avoiding the serious consequences of hypoglycemia. T...

journal_title：Indian journal of pharmaceutical sciences

authors： Dasoondi AS,Singh V,Voleti SR,Tiwari M

更新日期：2008-03-01 00:00:00

abstract：:Asymmetric membrane capsules are a type of osmotic drug delivery systems. They are nondisintegrating capsules, which utilize osmotic pressure to drive the drug outwards for controlled delivery. Preceded by systems such as elementary osmotic pump, controlled porosity osmotic pump, single composition osmotic tablet this...

journal_title：Indian journal of pharmaceutical sciences

authors： Sahoo PK,Makar H

更新日期：2013-03-01 00:00:00

abstract：:Antianthelmintic activity of successive extracts (chloroform, acetone, ethanol and aqueous) of Nauclea orientalis leaves were evaluated separately on adult Indian earthworm (Pheretima posthuma) and compared with that of albendazole. It was found that the extracts exhibited, respectively dose-dependent action and inhib...

journal_title：Indian journal of pharmaceutical sciences

authors： Raghavamma ST,Rao NR

更新日期：2010-07-01 00:00:00

abstract：:A series of novel 2,3-disubstitutedquinazolin-4(3H)-ones have been synthesized by condensation of 2-substituted benzo[1,3]oxazine-4-ones and anthranilic acid. Synthesized compounds were evaluated for in vitro antiviral activity against HIV, HSV and vaccinia viruses. 5-Bromo-2-(6-bromo-4-oxo-2-phenyl-4H-quinazolin-3-yl...

journal_title：Indian journal of pharmaceutical sciences

authors： Selvam P,Murugesh N,Chandramohan M,Pannecouque C,DE Clercq E

更新日期：2010-11-01 00:00:00

abstract：:Malnutrition is widely prevalent among patients on hemodialysis. Malnutrition can be estimated using a fully quantitative scoring system Subjective Global Assessment-Dialysis Malnutrition Score which is simple, reliable and dynamic. The primary objective of the study was to assess the severity of malnutrition in patie...

journal_title：Indian journal of pharmaceutical sciences

authors： Janardhan V,Soundararajan P,Rani NV,Kannan G,Thennarasu P,Chacko RA,Reddy CU

更新日期：2011-01-01 00:00:00

abstract：:The present work describes a simple, precise and accurate HPLC method for estimation of montelukast sodium in bulk and in tablet dosage form. The separation was achieved by using octadecylsilane column (C18) and acetonitrile:1 mM sodium acetate adjusted to pH 6.3 with acetic acid in proportion of 90:10 v/v as mobile p...

journal_title：Indian journal of pharmaceutical sciences

authors： Singh RM,Saini PK,Mathur SC,Singh GN,Lal B

更新日期：2010-03-01 00:00:00

abstract：:Bacteria have developed multidrug resistance against available antimicrobial agents. Infectious diseases caused by these multidrug-resistant bacteria are major causes of morbidity and mortality in human beings. Synthetic drugs are expensive and inadequate for the treatment of diseases, causing side effects and ineffec...

journal_title：Indian journal of pharmaceutical sciences

authors： Venkatadri B,Arunagirinathan N,Rameshkumar MR,Ramesh L,Dhanasezhian A,Agastian P

更新日期：2015-11-01 00:00:00

abstract：:A derivative UV spectrophotometric and a reversed phase high-performance liquid chromatographic method for the determination of ciprofibrate in tablets was developed. The first-order derivative UV spectrophotometric method was found to be accurate with 100.57±0.97 recovery and precise with a coefficient of variation o...

journal_title：Indian journal of pharmaceutical sciences

authors： Jain PS,Jivani HN,Khatal RN,Surana SJ

更新日期：2012-03-01 00:00:00

abstract：:In the current research work an attempt was made to develop "Melt in mouth pellets" (Meltlets(®)) containing 40% herbal extract of soy isoflavones that served to provide antioxidants activity in menopausal women. The process of extrusion-spheronization was optimized for extruder speed, extruder screen size, spheroniza...

journal_title：Indian journal of pharmaceutical sciences

authors： Deshmukh K,Amin P

更新日期：2013-07-01 00:00:00

abstract：:A simple, accurate and sensitive spectroscopic method has been proposed for the assay of ciprofloxacin in tablet by least square treatment of fourier transform infrared spectrometric data obtained at the wavenumber corresponding to the carbonyl group centered at 1707 cm(-1). The method involves the extraction of the a...

journal_title：Indian journal of pharmaceutical sciences

authors： Pandey S,Pandey P,Tiwari G,Tiwari R,Rai AK

更新日期：2012-01-01 00:00:00

abstract：:Present study aims to prepare and evaluate niacin microspheres. Niacin-ethyl cellulose microspheres were prepared by water-in-oil-in-oil double emulsion solvent diffusion method. Spherical, free flowing microspheres having an entrapment efficiency of 72% were obtained. The effect of polymer-drug ratio, surfactant conc...

journal_title：Indian journal of pharmaceutical sciences

authors： Maravajhala V,Dasari N,Sepuri A,Joginapalli S

更新日期：2009-11-01 00:00:00

abstract：:Modification of polymers by covalent attachment of thiol bearing pendant groups is reported to impart many beneficial properties to them. Hence in the present study, sodium alginate-cysteine conjugate was synthesized by carbodiimide mediated coupling under varying reaction conditions and the derivatives characterized ...

journal_title：Indian journal of pharmaceutical sciences

authors： Jindal AB,Wasnik MN,Nair HA

更新日期：2010-11-01 00:00:00

abstract：:The formulations consisting of a hydrophilic and hydrophobic material were investigated for effect on drug-release pattern from the matrices. Gum damar and gum copal being water-insoluble were used to study the efficiency of combined matrices to sustain the release of drug. Hydroxypropyl methylcellulose K100M and dicl...

journal_title：Indian journal of pharmaceutical sciences

authors： Fulbandhe VM,Jobanputra CR,Wadher KJ,Umekar MJ,Bhoyar GS

更新日期：2012-05-01 00:00:00

abstract：:Floating matrix tablets of domperidone were developed to prolong gastric residence time and thereby increased drug bioavailability. Domperidone was chosen as a model drug because it is poorly absorbed from the lower gastrointestinal tract. The tablets were prepared by wet granulation technique, using polymers such as ...

journal_title：Indian journal of pharmaceutical sciences

authors： Prajapati ST,Patel LD,Patel DM

更新日期：2009-01-01 00:00:00