Comparative antibacterial activity of L-695,256, a carbapenem active against methicillin-resistant staphylococci.


:The activity of a new prototype carbapenem, L-695,256, against clinical isolates of gram-positive and gram-negative aerobes was studied in vitro by agar dilution. L-695,256 was highly active against methicillin-resistant and -susceptible isolates of staphylococci (MICs, 0.016 to 2 micrograms/ml) and against penicillin-resistant pneumococci (MICs, 0.016 to 0.064 micrograms/ml), irrespective of penicillin susceptibility. Activity against members of the family Enterobacteriaceae was less than that of imipenem, while Proteus mirabilis and Morganella morganii were more susceptible to L-695,256.


Rylander M,Rollof J,Jacobsson K,Norrby SR




Has Abstract


1995-05-01 00:00:00












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    journal_title:Antimicrobial agents and chemotherapy

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    journal_title:Antimicrobial agents and chemotherapy

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    journal_title:Antimicrobial agents and chemotherapy

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    authors: Alonso A,Sanchez P,Martínez JL

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    journal_title:Antimicrobial agents and chemotherapy

    pub_type: 杂志文章


    authors: Brajtburg J,Elberg S,Kobayashi GS,Medoff G

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    journal_title:Antimicrobial agents and chemotherapy

    pub_type: 杂志文章


    authors: Wood SC,McCashion RN,Lynch WH

    更新日期:1986-06-01 00:00:00