Circadian thyrotropin variations are preserved in normal pregnant women.

abstract：:Puberty is the result of increasing pulsatile secretion of the hypothalamic gonadotropin releasing hormone (GnRH), which stimulates the release of gonadotropins and in turn gonadal activity. In general in females, development of secondary sex characteristics due to the activity of the gonadal axis, i.e., the growth of...

journal_title：European journal of endocrinology

authors： Delemarre EM,Felius B,Delemarre-van de Waal HA

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:The risk of radiation-induced benign and malignant thyroid nodules is well known. OBJECTIVE:The aim of this study was to determine the occurrence of thyroid nodules and carcinomas after fractionated total body irradiation (TBI) preceding hematopoietic stem cell transplantation (HSCT) for malignant hematolog...

journal_title：European journal of endocrinology

authors： Vivanco M,Dalle JH,Alberti C,Lescoeur B,Yakouben K,Carel JC,Baruchel A,Léger J

更新日期：2012-08-01 00:00:00

abstract：Introduction:Pathologically high growth hormone (GH) and insulin-like growth factor-1 (IGF-1) levels in patients with acromegaly are associated with arthropathy. Several studies highlight the potential role of the GH/IGF-1 axis in primary osteoarthritis (OA). We aimed to disentangle the role of IGF-1 levels in primary ...

journal_title：European journal of endocrinology

authors： Pelsma ICM,Claessen KMJA,Slagboom PE,van Heemst D,Pereira AM,Kroon HM,Ramos YFM,Kloppenburg M,Biermasz NR,Meulenbelt IM

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:The type 2 deiodinase (D2) is a key enzyme for intracellular triiodothyronine (T(3)) generation. A single-nucleotide polymorphism in D2 (Thr92Ala) has been associated with increased insulin resistance in nondiabetic and type 2 diabetes (DM2) subjects. Our aim was to evaluate whether the D2 Thr92Ala polymorphi...

journal_title：European journal of endocrinology

authors： Dora JM,Machado WE,Rheinheimer J,Crispim D,Maia AL

更新日期：2010-09-01 00:00:00

abstract：:Osteoporosis is being increasingly recognised in paediatric practice as a consequence of several factors. These include the increasing complexity of chronic conditions and the associated treatments managed by paediatricians. In addition, the improved care provided to children with chronic illness has led to many of th...

journal_title：European journal of endocrinology

authors： Shaw NJ

更新日期：2008-12-01 00:00:00

abstract：:We examined excretion of urinary insulin-like growth factors I and II (IGF-I and IGF-II) and their major binding protein IGFBP-3 in comparison to their respective serum concentration in nine healthy female volunteers (median age 25 years, range 22-27) under baseline conditions and after stimulation with recombinant hu...

journal_title：European journal of endocrinology

authors： Tönshoff B,Blum WF,Vickers M,Kurilenko S,Mehls O,Ritz E

更新日期：1995-04-01 00:00:00

abstract：CONTEXT:The late presentation of steroid 5α-reductase-2 (SRD5A2) deficiency in females is poorly characterised. The ratios of 5α/5β-reduced metabolites of adrenal steroids in a urine steroid profile (USP) can give an indication of SRD5A2 deficiency, although the diagnostic cut-off for 5α/5β ratios are not clearly defin...

journal_title：European journal of endocrinology

authors： Berra M,Williams EL,Muroni B,Creighton SM,Honour JW,Rumsby G,Conway GS

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:The insulin-resistant state of the polycystic ovary syndrome (PCOS) was found to be associated with a decreased glucose transporter GLUT4 expression in the insulin target tissues. This study was performed to explore whether the well-known clinical, hormonal and metabolic efficacy of metformin or rosiglitazone...

journal_title：European journal of endocrinology

authors： Jensterle M,Janez A,Mlinar B,Marc J,Prezelj J,Pfeifer M

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVES:The French Acromegaly Registry records data of acromegalic patients' since 1992 in French, Belgian (Liège), and Swiss (Lausanne) centers. We studied the prevalence of diabetes in this population looking for risk factors. Patients from one of the centers (Reims) were then analyzed more thoroughly. METHODS:Th...

journal_title：European journal of endocrinology

authors： Fieffe S,Morange I,Petrossians P,Chanson P,Rohmer V,Cortet C,Borson-Chazot F,Brue T,Delemer B,French Acromegaly Registry.

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVES:Gel filtration chromatography (GFC), the gold standard for macroprolactinaemia (MPRL) diagnosis, is a slow, costly and labour-intensive method. To limit the number of GFC required, we evaluated two screening tests for MPRL: prolactin (PRL) recovery after polyethylene glycol (PEG) precipitation and PRL concen...

journal_title：European journal of endocrinology

authors： Parlant-Pinet L,Harthé C,Roucher F,Morel Y,Borson-Chazot F,Raverot G,Raverot V

更新日期：2015-06-01 00:00:00

abstract：:Prostate growth is known to be controlled by steroids such as androgens and estradiol. For this reason steroids (estradiol, adrenal androgens) or steroid inhibitors are commonly used as palliative treatments for prostate carcinoma. In view of the pivotal role played by Ca2+ ions in cell proliferation, we decided to in...

journal_title：European journal of endocrinology

authors： Audy MC,Vacher P,Duly B

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:The aim was to evaluate changes of bone mineral density (BMD) and markers of bone turnover in healthy adolescents, and in adolescent users of combined oral contraceptives (COCs) with different ethinylestradiol (EE) contents. METHODS:In this prospective crossover study, 56 healthy females (15-19.5 years) wit...

journal_title：European journal of endocrinology

authors： Cibula D,Skrenkova J,Hill M,Stepan JJ

更新日期：2012-06-01 00:00:00

abstract：:Exogenous growth hormone (hGH) administration in humans attenuates the endogenous growth hormone (GH) response to some pharmacological stimuli; in particular, pretreatment with hGH completely blocks the serum GH response to growth hormone-releasing hormone. In order to evaluate the mechanism(s) whereby opiods induce G...

journal_title：European journal of endocrinology

authors： Fanciulli G,Oliva O,Tomasi PA,Pala A,Bertoncelli A,Dettori A,Delitala G

更新日期：1996-01-01 00:00:00

abstract：:Signalling of receptor activator of nuclear factor-κB (RANK) ligand (RANKL) through RANK is a critical pathway to regulate the differentiation and activity of osteoclasts and, hence, a master regulator of bone resorption. Increased RANKL activity has been demonstrated in diseases characterised by excessive bone loss s...

journal_title：European journal of endocrinology

authors： Tsourdi E,Rachner TD,Rauner M,Hamann C,Hofbauer LC

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of long-term GH in GH-deficient adults, as predicted by IGF-I levels. METHODS:Patients received GH, 5 microg/kg per day for 1 Month and 10 microg/kg per day for another 12-30 Months. Changes in body composition, cardiac structure/function, serum lipids and quality of life were meas...

journal_title：European journal of endocrinology

authors： Ezzat S,Fear S,Gaillard RC,Gayle C,Marcovitz S,Mattioni T,Nussey S,Rees A,Svanberg E

更新日期：2003-12-01 00:00:00

abstract：Background/objective:Data on metabolic impairments in Cushing's syndrome and GH deficiency all suggest that the relationship between cortisol and GH/IGF-I axis in obesity may have a role in the related diseases. However, studies focusing only on one of these hormones are often controversial in paediatrics. We aimed to ...

journal_title：European journal of endocrinology

authors： Ricotti R,Solito A,Mariotti Zani E,Caputo M,Genoni G,Barone-Adesi F,Mancioppi V,Agosti E,Aimaretti G,Bellone S,Prodam F

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Autoimmune polyendocrine syndrome type I (APS I) is a monogenic disease affecting endocrine glands and other organs due to mutations of the autoimmune regulator (AIRE) gene. There is a wide variability in clinical phenotypes in patients with APS I, which makes the diagnosis a challenge. OBJECTIVE:To screen ...

journal_title：European journal of endocrinology

authors： F Magitta N,Pura M,S Bøe Wolff A,Vanuga P,Meager A,M Knappskog P,Husebye ES

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND/AIM:Our previous studies showed that administration of dexamethasone plus food increased serum leptin levels 100% more than dexamethasone alone. We hypothesized that this increase in leptin from the meal could result directly from the provision of fuel metabolites rather than from the meal-induced rise in in...

journal_title：European journal of endocrinology

authors： Garcia-Lorda P,Nash W,Roche A,Pi-Sunyer FX,Laferrere B

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVE:We intend to assess the utility of the high-sensitivity C-reactive protein (hs-CRP) as a marker of cardiovascular risk in obese children and adolescents. METHODS:The study included children and adolescents between 6 and 18 years of age with a body mass index (BMI) higher than 2 SDS. All the patients had thei...

journal_title：European journal of endocrinology

authors： Soriano-Guillén L,Hernández-García B,Pita J,Domínguez-Garrido N,Del Río-Camacho G,Rovira A

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:Surgery remains a common form of treatment for sellar and parasellar tumors involving the pituitary gland and adjacent structures. Studies have suggested that pituitary surgery procedures performed at high-volume centers are associated with less adverse outcomes, yet it remains unclear which types of patients...

journal_title：European journal of endocrinology

authors： Mukherjee D,Zaidi HA,Kosztowski T,Chaichana KL,Salvatori R,Chang DC,Quiñones-Hinojosa A

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:Non-thyroidal illness (NTI) is associated with alterations in thyroid hormone metabolism. Whether morphological changes of the thyroid gland accompany NTI is unknown. The aim of the present study was to describe thyroid morphology in patients with lethal non-thyroidal disease. DESIGN:In an autopsy study 267 ...

journal_title：European journal of endocrinology

authors： De Jongh FE,Jöbsis AC,Elte JW

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:Previous studies have demonstrated a high prevalence of thyroperoxidase antibodies (TPOAb) and autoimmune hypothyroidism in breast cancer (BC). These studies have been performed in BC patients generally 20-30 days after mastectomy. It is known that stress may have an influence on the immune system and a rela...

journal_title：European journal of endocrinology

authors： Giustarini E,Pinchera A,Fierabracci P,Roncella M,Fustaino L,Mammoli C,Giani C

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVE:An increased tendency towards thromboembolic events is observed in patients with Cushing's syndrome. There are much fewer publications available about thromboembolic complications in patients with subclinical Cushing's syndrome (SCS). Therefore, a question arises whether hemostatic disturbances appear in this...

journal_title：European journal of endocrinology

authors： Swiatkowska-Stodulska R,Kaniuka-Jakubowska S,Wisniewski P,Skibowska-Bielinska A,Sworczak K

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:Circulating IGF1 declines with age while ill-health increases. Controversy remains whether differences in the levels of IGF1 and its binding proteins 1 and 3 (IGFBP1 and IGFBP3) determine health outcomes during ageing. We examined associations of IGF1, IGFBP1 and IGFBP3 with all-cause and cardiovascular morta...

journal_title：European journal of endocrinology

authors： Yeap BB,Chubb SA,McCaul KA,Ho KK,Hankey GJ,Norman PE,Flicker L

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:Thyroidal production of triiodothyronine (T(3)) is absent in patients who have undergone total thyroidectomy. Therefore, relative T(3) deficiency may occur during postoperative levothyroxine (L-T(4)) therapy. The objective of this study was to evaluate how the individual serum T(3) level changes between preop...

journal_title：European journal of endocrinology

authors： Ito M,Miyauchi A,Morita S,Kudo T,Nishihara E,Kihara M,Takamura Y,Ito Y,Kobayashi K,Miya A,Kubota S,Amino N

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Ki-67 labeling index (LI) is currently regarded as a useful prognostic marker of pituitary adenoma (PA) clinical behavior, although its relevance as a reliable clinical indicator is far from being universally accepted, since both validations and criticisms are found in the literature. Minichromosome maintena...

journal_title：European journal of endocrinology

authors： Coli A,Asa SL,Fadda G,Scannone D,Chiloiro S,De Marinis L,Lauretti L,Ranelletti FO,Lauriola L

更新日期：2016-03-01 00:00:00

abstract：:Pituitary tumours express both somatostatin and dopamine receptors. Medical treatment with somatostatin analogues is a cornerstone of GH- and TSH-secreting tumours, while treatment with dopamine agonists is a cornerstone of prolactin-secreting tumours. Dopamine agonists have also demonstrated some efficacy in patients...

journal_title：European journal of endocrinology

authors： Colao A,Filippella M,Pivonello R,Di Somma C,Faggiano A,Lombardi G

更新日期：2007-04-01 00:00:00

abstract：:Osteopetrosis is a rare metabolic bone disease characterized by a generalized increase in skeletal mass. It is inherited in a number of mammalian species, including man, and results from a congenital defect in the development or function of the osteoclasts. The consequent impairment of bone resorption prevents formati...

journal_title：European journal of endocrinology

authors： Felix R,Hofstetter W,Cecchini MG

更新日期：1996-02-01 00:00:00

abstract：:The effects of water deprivation for 3 days were studied in pregnant rats and their fetuses on day 21 of gestation. Maternal water deprivation induced a significant decrease of the body weight in both maternal and fetal rats. This weight loss was accompanied by significant increases in plasma osmolality and haematocri...

journal_title：European journal of endocrinology

authors： Deloof S,De Seze C,Montel V,Chatelain A

更新日期：1999-08-01 00:00:00

abstract：OBJECTIVES:The aim of the present study was to determine vascular endothelial growth factor (VEGF), prostaglandin E(2) (PGE(2)) and active renin levels in patients with hormonally active adrenal tumours. DESIGN:The study was comprised of 16 patients with primary aldosteronism, 13 patients with active Cushing's syndrom...

journal_title：European journal of endocrinology

authors： Zacharieva S,Atanassova I,Orbetzova M,Nachev E,Kalinov K,Kirilov G,Shigarminova R,Ivanova R,Dashev G

更新日期：2004-03-01 00:00:00