Osteoporosis-associated fracture and diabetes.

abstract：:Parathyroid hormone (PTH) is the major secretory product of the parathyroid glands, and in hypocalcemic conditions, can enhance renal calcium reabsorption, increase active vitamin D production to increase intestinal calcium absorption, and mobilize calcium from bone by increasing turnover, mainly but not exclusively i...

journal_title：Endocrinology and metabolism clinics of North America

authors： Goltzman D

更新日期：2018-12-01 00:00:00

abstract：:The incidence, clinical presentation, and types of thyroid cancers presenting in childhood are reviewed. The role of antecedent radiation in papillary and follicular thyroid cancers and genetics of medullary thyroid carcinoma are discussed. Unique aspects of therapy and prognosis for the pediatric patient with thyroid...

journal_title：Endocrinology and metabolism clinics of North America

authors： Gorlin JB,Sallan SE

更新日期：1990-09-01 00:00:00

abstract：:Dyslipidemia now is recognized as a significant potential adverse event in HIV-infected patients who are receiving antiretroviral therapy. HIV-infected persons who have hyperlipidemia should be managed similarly to those without HIV infection in accordance with the National Cholesterol Education Program. Providers mus...

journal_title：Endocrinology and metabolism clinics of North America

authors： Aberg JA

更新日期：2009-03-01 00:00:00

abstract：:Identifying patients with a high risk of fracture and monitoring a patient's therapeutic response are important. Current methods to evaluate the risk of fracture include the measurement of bone mineral density as well as other risk factors, including those associated with the risk of falling. Several considerations ar...

journal_title：Endocrinology and metabolism clinics of North America

authors： Sowers M

更新日期：1997-03-01 00:00:00

abstract：:In this article, an overview is presented of hypophysitis in terms of current clinical and experimental findings, with discussion of the anatomic and histopathologic classification of primary hypophysitis and factors associated with secondary hypophysitis. In addition, discusses the pathophysiology, clinical features,...

journal_title：Endocrinology and metabolism clinics of North America

authors： Fukuoka H

更新日期：2015-03-01 00:00:00

abstract：:The pathogenesis of atherosclerosis in human immunodeficiency virus (HIV)-infected individuals is incompletely understood and appears to be multifactorial. Proatherogenic changes in blood and tissue lipids are associated with an increased risk of cardiovascular disease among HIV-infected subjects, and these changes ma...

journal_title：Endocrinology and metabolism clinics of North America

authors： Kelesidis T,Currier JS

更新日期：2014-09-01 00:00:00

abstract：:Ethnicity is a complex yet important construct and an independent risk factor for diabetic heart disease (DHD) with paramount clinical significance. Clinicians should try to better understand the role of ethnicity through more questions. The risk of DHD is modified by ethnicity through more questions. The risk of DHD ...

journal_title：Endocrinology and metabolism clinics of North America

authors： Dave JK,Kamdar VV

更新日期：2006-09-01 00:00:00

abstract：:The degree of hyperglycemia may be an important predictor of morbidity and mortality among patients with MI or stroke, and in those undergoing surgical procedures including coronary artery bypass. Hyperglycemia should be aggressively controlled from the time of hospital admission regardless of the patient's primary me...

journal_title：Endocrinology and metabolism clinics of North America

authors： Levetan CS,Magee MF

更新日期：2000-12-01 00:00:00

abstract：:Urinary stone disease is the only clinical presentation in patients with cystinuria. Two genes have been associated with type I (SLC3A1) and non-type I (SLC7A9) cystinuria and multiple mutations of these genes have been identified. The type I form is completely recessive while the non-type I form is incompletely reces...

journal_title：Endocrinology and metabolism clinics of North America

authors： Shekarriz B,Stoller ML

更新日期：2002-12-01 00:00:00

abstract：:Obesity is associated with a spectrum of metabolic and cardiovascular disorders, including hypertension. Both the degree and the distribution of excess adipose tissue impact on the risk of hypertension and associated cardiovascular diseases. The mechanisms that may lead to hypertension in obese individuals include inc...

journal_title：Endocrinology and metabolism clinics of North America

authors： Hsueh WA,Buchanan TA

更新日期：1994-06-01 00:00:00

abstract：:Transgender persons receiving gender-affirming hormone therapy and procedures may face specific skin conditions. Skin diseases in transgender patients often are underdiagnosed and underrecognized despite their important impact on quality of life and mental health. This article discusses pathophysiology, diagnosis, and...

journal_title：Endocrinology and metabolism clinics of North America

authors： Yeung H,Kahn B,Ly BC,Tangpricha V

更新日期：2019-06-01 00:00:00

abstract：:The recent discovery of specific and sensitive biochemical markers reflecting the overall rate of bone formation and bone resorption has markedly improved the noninvasive assessment of bone turnover in various metabolic bone diseases, especially in osteoporosis. The immunoassay of human osteocalcin, recognizing the in...

journal_title：Endocrinology and metabolism clinics of North America

authors： Garnero P,Delmas PD

更新日期：1998-06-01 00:00:00

abstract：:With apparent failure of SU drug therapy, the management of NIDDM patients becomes even more challenging. The following sequence of actions is recommended. 1. Situational dietary noncompliance (eg, a prolonged vacation or a recent period of family or occupational stress) should be treated first by renewed regular cont...

journal_title：Endocrinology and metabolism clinics of North America

authors： Genuth S

更新日期：1992-06-01 00:00:00

abstract：:The regulation of energy balance is enormously complex, with numerous genetic, hormonal, neural/behavioral, and societal influences. Although the current epidemic of obesity has its underpinnings in the changes in culture during the last half century, the role of the neuroendocrine system in the genesis of obesity is ...

journal_title：Endocrinology and metabolism clinics of North America

authors： Lustig RH

更新日期：2001-09-01 00:00:00

abstract：:Based on the 2010 version, the 2017 World Health Organization (WHO 2017) classification is for pancreatic neuroendocrine neoplasms (PanNEN). The WHO 2017 classification introduces the novel well-differentiated neuroendocrine tumor of high grade (NET G3). A sharp distinction between NET and poorly differentiated neuroe...

journal_title：Endocrinology and metabolism clinics of North America

authors： Inzani F,Petrone G,Rindi G

更新日期：2018-09-01 00:00:00

abstract：:This article explores many of the ophthalmologic aspects of thyroid-related orbitopathy. The eight main areas of clinical concern--ocular comfort, optic nerve function, exophthalmos, eyelid position, diplopia, cosmesis, soft-tissue signs, and psychologic factors--are discussed so that practitioners may be more secure ...

journal_title：Endocrinology and metabolism clinics of North America

authors： Gladstone GJ

更新日期：1998-03-01 00:00:00

abstract：:The authors provide an extensive and comprehensive review of dyslipoproteinemia in children. An effective program for CVD reduction in this population will include an accessible screening program to identify high-risk children, high-quality measurements of TC and LP-C, careful follow-up of screening results with multi...

journal_title：Endocrinology and metabolism clinics of North America

authors： Franklin FA Jr,Brown RF,Franklin CC

更新日期：1990-06-01 00:00:00

abstract：:The prevalence of low-risk differentiated thyroid cancer (DTC) is dramatically increasing because of superior diagnostic imaging technologies. Remote-access endoscopic thyroidectomy is becoming more popular for the lack of a noticeable neck scar. Transoral endoscopic thyroidectomy, vestibular approach (TOETVA) is the ...

journal_title：Endocrinology and metabolism clinics of North America

authors： Jongekkasit I,Jitpratoom P,Sasanakietkul T,Anuwong A

更新日期：2019-03-01 00:00:00

abstract：:Ambiguity of the external genitalia may be based on disordered steroid biosynthesis or may arise from fundamental genetic and chromosomal abnormalities that produce failure of gonadogenesis. This article first discusses congenital adrenal hyperplasia and then considers the diverse abnormalities that cause disordered g...

journal_title：Endocrinology and metabolism clinics of North America

authors： New MI,Josso N

更新日期：1988-06-01 00:00:00

abstract：:More than 80% of women experience psychologic or physical symptoms in the late reproductive years, with varying degrees of severity and disruption in their lives. Patients and clinicians have misconceptions about what changes are considered "normal" or"abnormal" during this period. Of importance to clinicians, large-s...

journal_title：Endocrinology and metabolism clinics of North America

authors： Gracia CR,Freeman EW

更新日期：2004-12-01 00:00:00

abstract：:In the last few years, there have been remarkable advances in the development of new and more sophisticated genetic techniques. These have allowed a better understanding of the molecular mechanisms of genetically determined pediatric endocrine disorders and are paving the way for a radical change in diagnosis and trea...

journal_title：Endocrinology and metabolism clinics of North America

authors： Tenore A,Driul D

更新日期：2009-09-01 00:00:00

abstract：:Hypergonadotropic forms of amenorrhea in young women are many and varied, and the disorder is not nearly as uncommon as previously believed. It is likely that all physicians seeing women with amenorrhea will encounter this disorder. Careful evaluation is warranted to eliminate any associated autoimmune disorders. Beca...

journal_title：Endocrinology and metabolism clinics of North America

authors： Rebar RW,Cedars MI

更新日期：1992-03-01 00:00:00

abstract：:Elevated plasma concentrations of lipoprotein(a) (Lp[a]) are an emerging risk factor for the development of coronary heart disease (CHD). Recent genetic and epidemiologic data have provided strong evidence for a causal role of Lp(a) in CHD. Despite these developments, which have attracted increasing interest from clin...

journal_title：Endocrinology and metabolism clinics of North America

authors： Koschinsky ML,Boffa MB

更新日期：2014-12-01 00:00:00

abstract：:Morbid obesity has reached epidemic proportions in the United States. Unfortunately, medical interventions have been largely ineffective in this growing population. Currently bariatric surgery is the most effective intervention in managing morbid obesity and its comorbidities. As more patients become eligible for and ...

journal_title：Endocrinology and metabolism clinics of North America

authors： Stocker DJ

更新日期：2003-06-01 00:00:00

abstract：:Male infertility is a common problem but only about one quarter of patients have specific or defined conditions that make them either sterile or severely infertile. About half of these patients have untreatable primary seminiferous tubule failure, and donor insemination or adoption are the only possibilities of having...

journal_title：Endocrinology and metabolism clinics of North America

authors： Baker HW

更新日期：1994-12-01 00:00:00

abstract：:This systematic review highlights the uncertainty about the safety and efficacy of glucocorticoid withdrawal in many chronic diseases, elucidating the need for further research in this area. The problem of glucocorticoid withdrawal seems to be good example for wide variation in physicians' approaches to weaning patien...

journal_title：Endocrinology and metabolism clinics of North America

authors： Richter B,Neises G,Clar C

更新日期：2002-09-01 00:00:00

abstract：:Calcitriol (1,25-dihydroxyvitamin D(3)), the hormonally active form of vitamin D, exerts growth inhibitory and prodifferentiating effects on many malignant cells and retards tumor growth in animal models. Calcitriol is being evaluated as an anticancer agent in several human cancers. The mechanisms underlying the antic...

journal_title：Endocrinology and metabolism clinics of North America

authors： Krishnan AV,Trump DL,Johnson CS,Feldman D

更新日期：2010-06-01 00:00:00

abstract：:The study of genetic syndromes associated with adrenocortical tumors (Beckwith-Wiedemann, Li-Fraumeni, McCune-Albright, Carney, and multiple endocrine neoplasia type 1) has shed light on the molecular basis of tumorigenesis. Abnormalities at the 11p15 locus appear as crucial and frequent events found specifically in m...

journal_title：Endocrinology and metabolism clinics of North America

authors： Gicquel C,Bertherat J,Le Bouc Y,Bertagna X

更新日期：2000-03-01 00:00:00

abstract：:This review provides an overview of the safety of growth hormone replacement therapy in individuals previously treated for cancer. The review focuses on the risk of disease recurrence and second neoplasm occurrence with special attention to data on childhood cancer survivors. ...

journal_title：Endocrinology and metabolism clinics of North America

authors： Chemaitilly W,Robison LL

更新日期：2012-12-01 00:00:00

abstract：:The liver is key to glucose homeostasis. Any disruption of its metabolism, structural integrity, or intracellular dynamics may alter the liver's ability to maintain normal glucose homeostasis. When such disruption affects hepatic glucose output, hypoglycemia may eventuate. Multiple drugs including alcohol may alter th...

journal_title：Endocrinology and metabolism clinics of North America

authors： Arky RA

更新日期：1989-03-01 00:00:00