Characterization of neurotrophic activity in the silicone-chamber model for nerve regeneration.

Abstract:

:In the present study, the authors reevaluated the temporal course and properties of neurotrophic activities present in the fluid accumulating in the silicone-chamber model for nerve regeneration. The fluid collected from silicone chambers was tested in four different dissociated neuronal cell cultures. Furthermore, the activity of the chamber fluid was examined, using a cell blot technique. There was one major peak of neurotrophic activity and this activity peaked early, about 3 to 6 hr after nerve injury. Results also indicate that the chamber fluid contains at least two types of neurotrophic activities, namely nerve growth factor and ciliary neurotrophic factor.

journal_name

J Reconstr Microsurg

authors

Danielsen N,Varon S

doi

10.1055/s-2007-1006537

subject

Has Abstract

pub_date

1995-05-01 00:00:00

pages

231-5

issue

3

eissn

0743-684X

issn

1098-8947

journal_volume

11

pub_type

杂志文章
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