Two novel mutations affecting the same splice site of PKD1 correlate with different phenotypes in ADPKD.

abstract：AIM:To investigate the therapeutic effects of oral carbonic adsorbent on rats with early-stage renal failure. METHODS:The early-stage renal failure model was established with three-fourth subtotal nephrectomy Wistar rats. Four weeks after the subtotal nephrectomy, the rats were randomly divided into four groups: (1) a...

journal_title：Renal failure

authors： Tan X,He J,Cao X,Zou J,Liu H,Ding X

更新日期：2015-03-01 00:00:00

abstract：:Depression is common in patients with end-stage renal disease (ESRD) and is associated with increased mortality and morbidity. Several investigators have estimated that depression occurs in about 20% to 30% of dialysis patients. The aim of this study was to investigate the relationship between depression, some laborat...

journal_title：Renal failure

authors： Dogan E,Erkoc R,Eryonucu B,Sayarlioglu H,Agargun MY

更新日期：2005-01-01 00:00:00

abstract：:This article describes several topics necessary for understanding the psychological impact of disasters. Topics discussed include characteristics of disaster that impact psychological response, stages of response, factors influencing individual and collective trauma, and important aspects of psychological intervention...

journal_title：Renal failure

authors： Flynn BW

更新日期：1997-09-01 00:00:00

abstract：RATIONAL:The inhibition of renin-angiotensin-aldosterone system (RAAS) is a major strategy for slowing the progression of chronic kidney disease (CKD). The utility of anti-RAAS agents in patients with congenital or acquired solitary kidney is still controversial. OBJECTIVE:A systematic literature review was conducted....

journal_title：Renal failure

authors： Simeoni M,Armeni A,Summaria C,Cerantonio A,Fuiano G

更新日期：2017-11-01 00:00:00

abstract：:Substances toxic to the kidney are legion in the modern world. The sheer number and variety, their mutual interactions and, metabolism within the body are a challenge to research. Moreover, the kidney is especially prone to injury owing to its physiology. Acute kidney injury (AKI) induced by poisonous or primarily nep...

journal_title：Renal failure

authors： Petejova N,Martinek A,Zadrazil J,Teplan V

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Experimental studies have shown that increased levels of parathyroid hormone (PTH) in uremia may cause elevation of intracellular calcium, predisposing to insulin resistance and lipid metabolism abnormalities. Administration of calcium-channel blockers (CCBs) in these models protects against the development ...

journal_title：Renal failure

authors： Zanos S,Mitsopoulos E,Sakellariou G

更新日期：2005-01-01 00:00:00

abstract：:Diabetic nephropathy (DN) has become the most common pathogenesis of end-stage renal disease. Plasminogen activator inhibitor-1 (PAI-1) plays an important role in the pathogenesis of DN. A meta-analysis was conducted to investigate the association between 4 G/5 G variants in the PAI-1 gene and DN susceptibility. Datab...

journal_title：Renal failure

authors： Xue C,Nie W,Zhou C,Yu F,Wang DM,Dai B,Mei CL

更新日期：2014-04-01 00:00:00

abstract：:Vascular calcification (VC) is an important promoter of cardiovascular disease (CVD) in patients undergoing peritoneal dialysis (PD). Several indices can be used to evaluate VC, including the abdominal aortic calcification index (AACI) and carotid artery intima-media thickness (IMT); however, simpler and lesser expens...

journal_title：Renal failure

authors： Yang N,Yang W,Cui W,Zhou D,Du X,Li L

更新日期：2020-11-01 00:00:00

abstract：:Antenatal hydronephrosis (AHN), defined as dilatation of renal pelvis and/or calyces, is the most frequently detected antenatal abnormality. However, postnatal management of AHN is controversial. The purpose of this study was to describe the clinical outcomes of infants with AHN and to contribute to the definition of ...

journal_title：Renal failure

authors： Gökaslan F,Yalçınkaya F,Fitöz S,Özçakar ZB

更新日期：2012-01-01 00:00:00

abstract：:This study was aimed to investigate the therapeutic potential of coenzyme Q10 and its combination with sitagliptin in experimentally induced diabetic nephropathy. The diabetic rats were treated with coenzyme Q10 or sitagliptin and their concomitant administration. Various parameters of renal function like serum creati...

journal_title：Renal failure

authors： Maheshwari R,Balaraman R,Sen AK,Shukla D,Seth A

更新日期：2017-11-01 00:00:00

abstract：:Acute renal failure (ARF) is one of the most frequent and potentially life threatening complications following bone marrow transplantation (BMT). Several renal syndromes that occur are either unique or occur with a disproportionate frequency post-BMT. Clinically ARF can be classified according to the time of onset pos...

journal_title：Renal failure

authors： Pulla B,Barri YM,Anaissie E

更新日期：1998-05-01 00:00:00

abstract：:Despite advanced techniques of renal replacement therapy the overall mortality of patients with ARF is still high. The majority of patients with ARF requiring dialysis are those with nontraumatic ARF. In a retrospective study we compared the causes of nontraumatic ARF, the risk factors for the development of renal fai...

journal_title：Renal failure

authors： Schmekal B,Pichler R,Biesenbach G

更新日期：2004-01-01 00:00:00

abstract：:This report describes a patient who developed acute rhabdomyolysis and acute renal failure following the application of MAST trousers associated with an overdose of diflunisal. This association has not previously been reported. ...

journal_title：Renal failure

authors： Pilmore H,Walker RJ

更新日期：1993-01-01 00:00:00

abstract：:Paraproteins or monoclonal proteins are the result of clonal B-cell or plasma cell proliferation of a malignant, premalignant or non-malignant nature. Monoclonal proteins may consist of intact immunoglobulin molecules or of heavy or light chains only. Depending on their rate of production and/or secretion they may acc...

journal_title：Renal failure

authors： Maniatis A

更新日期：1998-11-01 00:00:00

abstract：:Cold preservation has greatly facilitated the use of cadaveric kidneys for renal transplantation, but, clearly, damage occurs during both the preservation episode and the reperfusion phase (following transplantation). The aims of this study were twofold: to develop an in vivo model that was capable of evaluating renal...

journal_title：Renal failure

authors： Saba H,Munusamy S,Macmillan-Crow LA

更新日期：2008-01-01 00:00:00

abstract：:The single dose administration of the aminonucleoside of puromycin (PAN) induces a nephrotic syndrome in rats characterized by massive proteinuria and progressive histologic changes. This model of acute parenchymal nephritis is thought to be mediated by the renal recruitment of monocytes and macrophages. To investigat...

journal_title：Renal failure

authors： Berens KL,Verani RR,Luke DR

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVES:Extracorporeal shock wave (ESW) lithotripsy is the preferred treatment modality for uncomplicated kidney stones. More recently free oxygen radical production following ESW application has been considered to be crucial in shock wave-induced renal damage. It has been shown that ozone therapy (OT) has ameliorat...

journal_title：Renal failure

authors： Uğuz S,Demirer Z,Uysal B,Alp BF,Malkoc E,Guragac A,Turker T,Ateş F,Karademir K,Ozcan A,Yildirim I,Korkmaz A,Guven A

更新日期：2016-07-01 00:00:00

abstract：:Hypertonic glycerol injection is one of the most frequently used models of experimental acute renal failure. Late structural changes such as interstitial fibrosis in the renal cortex and tubular atrophy have been detected after severe acute tubular necrosis (ATN). The aim of this study was to investigate the expressio...

journal_title：Renal failure

authors： de Jesus Soares T,Costa RS,de Mattos Coelho R,Alves da Silva CG,Coimbra TM

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Although adequate peritoneal dialysis is not well defined, Kt/Vurea has been used as an index, and various values have been proposed. However, conflicting evidence existed regarding the appropriateness of using Kt/Vurea to define dialysis adequacy and its optimal value. Therefore, the present study performed...

journal_title：Renal failure

authors： Zhe XW,Shan YS,Cheng L,Tian XK,Wang T

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Diabetic kidney disease (DKD) is a leading cause of end-stage renal disease (ESRD). Renin-angiotensin-aldosterone system (RAAS) plays a critical role in the development of DKD with angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) being the mainstay of treatment. System...

journal_title：Renal failure

authors： Dhakarwal P,Agrawal V,Kumar A,Goli KM,Agrawal V

更新日期：2014-07-01 00:00:00

abstract：RATIONAL:Obstetrical complications are the commonest causes of Renal Cortical Necrosis (RCN). However, the overall incidence of RCN in obstetric acute kidney injury in developing countries has been decreasing in recent years. OBJECTIVE:The aim of this study was to evaluate the changing profile of RCN in obstetric AKI ...

journal_title：Renal failure

authors： Prakash J,Pant P,Singh AK,Sriniwas S,Singh VP,Singh U

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Asymmetric dimethylarginine (ADMA) as a uremia toxin is accumulated in end-stage renal disease (ESRD) patients. Elevated ADMA level has been shown to be predictive of cardiovascular diseases (CVDs) and all-cause mortality in ESRD. Therefore, we investigated the removal of ADMA by different dialysis treatment...

journal_title：Renal failure

authors： Zhang DL,Liu J,Liu S,Zhang Y,Liu WH

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Long-term peritoneal exposure to high glucose in the peritoneal dialysis (PD) solution may potentiate the development of peritoneal fibrosis in PD patients. The most important factor leading to peritoneal fibrosis may be injury of human peritoneal mesothelial cells (HPMC). Little is known about senescence of...

journal_title：Renal failure

authors： Cao D,Zhang M,Jiang C,Xue L,Sun C

更新日期：2012-01-01 00:00:00

abstract：:The characteristics of two established renal cell lines (LLC-PKI and OK) and of primary cultures of rabbit and human proximal tubule cells are described by summarizing the literature about specific properties retained by these cells in culture. Furthermore, comparative biochemical and functional properties are present...

journal_title：Renal failure

authors： Toutain H,Morin JP

更新日期：1992-01-01 00:00:00

abstract：:Acute renal failure (ARF) is a frequent complication in hospitalized patients and is strongly related to increase in mortality. In order to analyze the clinical outcome and the prognostic factors in hospital-acquired ARF, a prospective study was performed. Data from 200 patients with established ARF during the period ...

journal_title：Renal failure

authors： Barretti P,Soares VA

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:The pathogenesis of the development of IgA nephropathy has not been clear up to now. At present, some studies revealed that the mTOR pathway may participate in IgA nephropathy; however, the mechanism has not been systematically studied. In this study, we established an IgAN rat model to investigate the prote...

journal_title：Renal failure

authors： Guo N,Liu S,Bow LM,Cui X,Zhang L,Xu S,Lu S,Tian J

更新日期：2019-11-01 00:00:00

abstract：:Secondary hyperparathyroidism (SHP) is a frequent complication of long-term dialysis patients, and surgical parathyroidectomy remains necessary in patients resistant to medical therapy. The present paper reports single center results in subtotal parathyroidectomy, presenting diagnostic procedure, indications for parat...

journal_title：Renal failure

authors： Jovanovic DB,Pejanovic S,Vukovic L,Djukanovic L,Jankovic R,Kalezic N,Paunovic I,Zivaljevic V

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Hypertension very often accompanies progression of chronic kidney disease (CKD) in children. A cross-sectional analysis of hypertension prevalence in dialyzed children in Poland was designed with a comparison with the data previously recorded 10 years earlier. METHODS:Two cohorts of children were analyzed: ...

journal_title：Renal failure

authors： Tkaczyk M,Stańczyk M,Miklaszewska M,Zachwieja K,Wierciński R,Stankiewicz R,Firszt-Adamczyk A,Zachwieja J,Borzęcka H,Zagożdżon I,Leszczyńska B,Medyńska A,Adamczyk P,Szczepańska M,Fendler W

更新日期：2017-11-01 00:00:00

abstract：:Secondary hyperparathyroidism is one of the most common complications of chronic renal failure (CRF). Its pathogenesis is multifactorial and still not completely understood. Pathological mechanism of hypocalcemia, hyperphosphatemia and calcitriol deficiency are basic characteristics of CRF and main reason for morpholo...

journal_title：Renal failure

authors： Jeren-Strujić B,Rozman B,Lambasa S,Jeren T,Marković M,Raos V

更新日期：2001-03-01 00:00:00

abstract：:A newly identified cytokine, osteoprotegerin (OPG) appears to be involved in the regulation of bone remodeling. In vitro studies suggest that OPG, a soluble member of the TNF receptor family of proteins, inhibits osteoclastogenesis by interrupting the intercellular signaling between osteoblastic stromal cells and oste...

journal_title：Renal failure

authors： Crisafulli A,Romeo A,Floccari F,Aloisi E,Atteritano M,Cincotta M,Aloisi C,Pizzoleo MA,Ruello A,Artemisia A,Valenti A,Frisina N,Teti D,Buemi M

更新日期：2005-01-01 00:00:00