Carbon dioxide insufflation can significantly reduce toilet use after colonoscopy: a double-blind randomized controlled trial.


BACKGROUND AND STUDY AIMS:Carbon dioxide (CO2) insufflation during colonoscopy can significantly decrease abdominal pain and bloating after the procedure, but its impact on the frequency and duration of toilet use remains unknown. The aim of this study was to assess the impact of CO2 insufflation on toilet use after screening colonoscopy. METHODS:From 138 average-risk individuals who underwent screening colonoscopy during March to August 2013, 120 were enrolled and randomized to receive either CO2 or air insufflation at colonoscopy. Both the colonoscopist and participant were blinded to the type of gas used. Abdominal pain and distension were assessed using a visual analog scoring system. The frequency and duration of toilet visits during a 2-hour postcolonoscopy period were recorded using a radiofrequency identification system. RESULTS:Baseline characteristics were similar in both groups in terms of age, sex, and procedure time. In the 2 hours after colonoscopy, 50 participants (83 %) in the air group and 18 participants (30 %) in the CO2 group (P < 0.001) used the toilet at least once. The mean (± SD) duration of each toilet visit was 5.93 ± 4.65 minutes in the air group and 1.53 ± 2.84 minutes in the CO2 group (P < 0.001). The abdominal discomfort score was lower in the CO2 group than in the air group both at the end of the colonoscopy (P < 0.001) and 2 hours later (P < 0.001). CONCLUSION:Insufflation with CO2 can significantly reduce abdominal discomfort and toilet use after colonoscopy. Use of this technique may help reduce patient burden and allow more efficient use of space in the endoscopy unit.






Hsu WF,Hu WH,Chen YN,Lai HH,Chen MK,Chang LC,Tu CH,Chou CK,Wang HP,Wu MS,Chiu HM




Has Abstract


2014-03-01 00:00:00












  • A new endoscopic balloon for sclerotherapy in active bleeding from esophageal varices.

    abstract::A new balloon for flexible endoscopes has been developed and used in 25 patients with esophageal varices: sclerotherapy was carried out as prophylaxis against rebleeding in 17 cases, and during active hemorrhage in 8 cases. The balloon was shown to be effective in controlling hemorrhage and enabling sclerosing injecti...


    pub_type: 杂志文章


    authors: Sciaretta G,Verri A,Malaguti P

    更新日期:1985-05-01 00:00:00

  • Cost-effectiveness studies in endoscopy: are they worth it?

    abstract::Cost-effectiveness analysis is currently in great demand. Evaluating the cost-effectiveness of endoscopy in comparison with surgical and radiological alternatives for diagnosis and therapy would appear particularly important, since the costs they incur may be substantial. However, several technical and practical issue...


    pub_type: 杂志文章


    authors: Sahai AV

    更新日期:2000-12-01 00:00:00

  • Prevalence of HNPCC in a series of consecutive patients on the first endoscopic diagnosis of colorectal cancer: a multicenter study. The Italian Collaborative Group.

    abstract:BACKGROUND AND STUDY AIMS:It is difficult to measure the prevalence of hereditary non-polyposis colorectal cancer (HNPCC) in geographical areas that do not have tumor registers, as is the case in the present study, and it was therefore decided to assess the prevalence in Italy using different methods. PATIENTS AND MET...


    pub_type: 临床试验,杂志文章,多中心研究


    authors: Riegler G,Savastano A,Selvaggi F,Ciociano R,Martino R,Riccio G,Iorio R,Ponti G,Carratú R,Borgheresi P,de Filippo G,Rossi GB,Tempesta AM,de Palma GD,Catanzano C,Russo P,Bianco MA,Piscitelli A,di Carlo V,Baldi V,Ava

    更新日期:1999-06-01 00:00:00

  • Non-biopsy detection of intestinal metaplasia and dysplasia in Barrett's esophagus: a prospective multicenter study.

    abstract:BACKGROUND AND STUDY AIMS:There have been no multicenter studies investigating the use of magnification chromoendoscopy (MCE) for the detection of intestinal metaplasia and dysplasia/cancer in Barrett's esophagus. Our aims were to assess the ability of MCE to predict the histological diagnosis (non-biopsy detection), t...


    pub_type: 杂志文章,多中心研究


    authors: Sharma P,Marcon N,Wani S,Bansal A,Mathur S,Sampliner R,Lightdale C

    更新日期:2006-12-01 00:00:00

  • Transendoscopic Doppler ultrasound: usefulness for diagnosis and treatment of vascular malformations.

    abstract::Vascular malformations of the GI tract can be treated by thermal methods, including the YAG laser. The diagnosis of these lesions is not always easy, and it is difficult to evaluate the completeness of therapy of these lesions. We investigated the value of Doppler ultrasound in this respect. The TVD-1 (Key Med) transe...


    pub_type: 杂志文章


    authors: Rutgeerts P,Vantrappen G,D'Heygere F,Broeckaert L

    更新日期:1988-05-01 00:00:00

  • Small-bowel capsule endoscopy diagnoses early and advanced neoplasms in asymptomatic patients with Lynch syndrome.

    abstract:BACKGROUND AND STUDY AIMS:Patients with Lynch syndrome are at increased risk of developing small-bowel adenocarcinoma, which usually has a bad prognosis and needs to be diagnosed early. Our aim was to evaluate the yield of capsule endoscopy and CT enteroclysis in this situation. PATIENTS AND METHODS:We performed a pro...


    pub_type: 杂志文章


    authors: Saurin JC,Pilleul F,Soussan EB,Manière T,D'Halluin PN,Gaudric M,Cellier C,Heresbach D,Gaudin JL,Capsule Commission of the French Society of Digestive Endoscopy (SFED).

    更新日期:2010-12-01 00:00:00

  • In vitro evaluation of the radial and axial force of self-expanding esophageal stents.

    abstract:BACKGROUND AND STUDY AIMS:Technological innovation in esophageal stent design has progressed over the past decades, but the association between the mechanical properties of stent design and clinical outcome is still poorly understood. In this study the radial force and axial force of currently available stent designs w...


    pub_type: 杂志文章


    authors: Hirdes MM,Vleggaar FP,de Beule M,Siersema PD

    更新日期:2013-12-01 00:00:00

  • Endoscopic submucosal dissection using the "Clutch Cutter" for early esophageal squamous cell carcinoma.

    abstract:BACKGROUND AND STUDY AIMS:To reduce the risk of complications related to the use of knives in endoscopic submucosal dissection (ESD), we developed the Clutch Cutter which can grasp and incise targeted tissue using electrosurgical current, similarly to a biopsy technique. The study aim was to evaluate the efficacy and s...


    pub_type: 临床试验,杂志文章


    authors: Akahoshi K,Minoda Y,Komori K,Motomura Y,Kubokawa M,Otsuka Y,Hamada S,Fukuda S,Iwao R,Gibo J,Oya M,Nakamura K

    更新日期:2013-12-01 00:00:00

  • Synergistic sedation with low-dose midazolam and propofol for colonoscopies.

    abstract:BACKGROUND AND STUDY AIMS:Patients undergoing colonoscopy are often sedated with benzodiazepines and long-acting opiates. Since low-dose midazolam also acts synergistically with short-acting propofol, we compared this synergistic sedation with a standard combination of midazolam and the opioid nalbuphine for colonoscop...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Reimann FM,Samson U,Derad I,Fuchs M,Schiefer B,Stange EF

    更新日期:2000-03-01 00:00:00

  • Use of the urologic resectoscope in rectal pathology.

    abstract::We have resected five sessile polyps and treated rectal hemorrhage using the urologic resectoscope that operates in an aqueous solution. It is our belief that working in an aqueous environment can avoid some of the drawbacks of the standard technique in an air environment. We think that this is a useful technique in d...


    pub_type: 杂志文章


    authors: Gaya J,Obrador A,Ozonas M,de Sala E

    更新日期:1983-07-01 00:00:00

  • Endoscopic subtypes of colorectal laterally spreading tumors (LSTs) and the risk of submucosal invasion: a meta-analysis.

    abstract:BACKGROUND AND STUDY AIMS:Many studies have reported on laterally spreading tumors (LSTs), but systematic reviews of the data to determine their risk of containing submucosal invasion (SMI) are lacking. We systematically screened and analyzed the available literature to provide a more solid basis for evidence-based tre...


    pub_type: 杂志文章,meta分析


    authors: Bogie RMM,Veldman MHJ,Snijders LARS,Winkens B,Kaltenbach T,Masclee AAM,Matsuda T,Rondagh EJA,Soetikno R,Tanaka S,Chiu HM,Sanduleanu-Dascalescu S

    更新日期:2018-03-01 00:00:00

  • Endoscopic management of enteral tubes in adult patients - Part 2: Peri- and post-procedural management. European Society of Gastrointestinal Endoscopy (ESGE) Guideline.

    abstract::ESGE recommends the "pull" technique as the standard method for percutaneous endoscopic gastrostomy (PEG) placement.Strong recommendation, low quality evidence.ESGE recommends the direct percutaneous introducer ("push") technique for PEG placement in cases where the "pull" method is contraindicated, for example in sev...


    pub_type: 杂志文章


    authors: Gkolfakis P,Arvanitakis M,Despott EJ,Ballarin A,Beyna T,Boeykens K,Elbe P,Gisbertz I,Hoyois A,Mosteanu O,Sanders DS,Schmidt PT,Schneider SM,van Hooft JE

    更新日期:2021-02-01 00:00:00

  • Esophageal varix hemorrhage and sclerotherapy--animal studies.

    abstract::Although endoscopic sclerosis for control of variceal hemorrhage is an old technique, many questions remain about the technique, its applications, and outcomes after use. This report summarizes recent data from animal studies that relate to clinical questions concerning esophageal varix hemorrhage and sclerotherapy. A...


    pub_type: 杂志文章,评审


    authors: Jensen DM,Machicado GA,Silpa M

    更新日期:1986-05-01 00:00:00

  • Upper gastrointestinal hemorrhage secondary to erosion of a biliary Wallstent in a woman with pancreatic cancer.

    abstract::A 77-year-old patient with unresectable pancreatic adenocarcinoma sustained a life-threatening, upper gastrointestinal hemorrhage 1 month after placement of a biliary Wallstent. Radiographic and endoscopic studies revealed a choledocho-arterio-enteric fistula caused by erosion of the stent through the posterior duoden...


    pub_type: 杂志文章


    authors: Gardiner MF,Long WB,Haskal ZJ,Lichtenstein GR

    更新日期:2000-08-01 00:00:00

  • Endocuff-assisted colonoscopy: a new accessory to improve adenoma detection rate? Technical aspects and first clinical experiences.

    abstract:BACKGROUND AND STUDY AIMS:The Endocuff is a new colonoscopy accessory that has been designed to improve both the adenoma detection rate and endoscope tip control. PATIENTS AND METHODS:A total of 50 Endocuff-assisted colonoscopies were analyzed retrospectively with regard to safety, procedural success, and complication...


    pub_type: 杂志文章


    authors: Lenze F,Beyna T,Lenz P,Heinzow HS,Hengst K,Ullerich H

    更新日期:2014-07-01 00:00:00

  • Do endoscopy capsules interfere with implantable cardioverter-defibrillators?

    abstract:BACKGROUND AND STUDY AIMS:Capsule endoscopy is already an established diagnostic tool, and the newly introduced capsule PillCam COLON is now entering clinical studies. Because of the very limited clinical experience in patients with implantable cardioverter-defibrillators (ICDs), it is generally recommended that capsul...


    pub_type: 杂志文章


    authors: Bandorski D,Irnich W,Brück M,Kramer W,Jakobs R

    更新日期:2009-05-01 00:00:00

  • Clinical outcome after endoscopic resection for superficial pharyngeal squamous cell carcinoma invading the subepithelial layer.

    abstract:BACKGROUND AND STUDY AIMS:The curability of endoscopic resection for superficial pharyngeal squamous cell carcinoma (SPSCC) has not been fully elucidated, particularly for lesions invading the subepithelial layer, which carry the risk of metastasis. The aim of this study was to evaluate the curative potential of endosc...


    pub_type: 杂志文章


    authors: Satake H,Yano T,Muto M,Minashi K,Yoda Y,Kojima T,Oono Y,Ikematsu H,Aoyama I,Morita S,Miyamoto S,Fujii S,Yoshizawa A,Ochiai A,Hayashi R,Kaneko K

    更新日期:2015-01-01 00:00:00

  • Overcoming the barriers to dissemination and implementation of quality measures for gastrointestinal endoscopy: European Society of Gastrointestinal Endoscopy (ESGE) and United European Gastroenterology (UEG) position statement.

    abstract::The European Society of Gastrointestinal Endoscopy (ESGE) has developed performance measures and established a framework for quality assessment for gastrointestinal endoscopy in Europe. Most national societies actively undertake initiatives to implement and explicitly endorse these quality indicators. Given this, ESGE...


    pub_type: 杂志文章


    authors: Bisschops R,Rutter MD,Areia M,Spada C,Domagk D,Kaminski MF,Veitch A,Khannoussi W,Gralnek IM,Hassan C,Messmann H,Ponchon T,Fockens P,Dignass A,Dinis-Ribeiro M

    更新日期:2021-02-01 00:00:00

  • Prediction of therapy in primary endoscopic retrograde cholangiopancreatography.

    abstract:BACKGROUND AND STUDY AIMS:It seems rational to perform endoscopic retrograde cholangiopancreatography (ERCP) if the probability of endoscopic therapy is high, but to carry out magnetic resonance cholangiopancreatography (MRCP) or endoscopic ultrasound (EUS) first if this probability is moderate or low. The aim of the p...


    pub_type: 杂志文章


    authors: Nathan T,Kjeldsen J,Schaffalitzky de Muckadell OB

    更新日期:2004-06-01 00:00:00

  • Comments on "Combined endoscopic submucosal dissection and transanal minimally invasive surgery for resection of large refractory rectal polyp".

    abstract:: ...


    pub_type: 评论,杂志文章


    authors: Valdes-Hernandez J

    更新日期:2019-03-01 00:00:00

  • Artificial intelligence for polyp detection during colonoscopy: a systematic review and meta-analysis.

    abstract:BACKGROUND: Artificial intelligence (AI)-based polyp detection systems are used during colonoscopy with the aim of increasing lesion detection and improving colonoscopy quality. PATIENTS AND METHODS: We performed a systematic review and meta-analysis of prospective trials to determine the value of AI-based polyp detec...


    pub_type: 杂志文章


    authors: Barua I,Vinsard DG,Jodal HC,Løberg M,Kalager M,Holme Ø,Misawa M,Bretthauer M,Mori Y

    更新日期:2020-06-17 00:00:00

  • Is endoscopic submucosal dissection an effective treatment for operable patients with clinical submucosal invasive early gastric cancer?

    abstract:BACKGROUND AND STUDY AIMS:Gastrectomy with lymph node dissection is the gold standard curative treatment for clinical submucosal invasive early gastric cancer (cSM EGC), but a relatively small number of operable patients with cSM EGC have undergone endoscopic submucosal dissection (ESD) instead because they refused sur...


    pub_type: 杂志文章


    authors: Suzuki H,Oda I,Nonaka S,Yoshinaga S,Saito Y

    更新日期:2013-01-01 00:00:00

  • The diagnostic accuracy of high-resolution endoscopy, autofluorescence imaging and narrow-band imaging for differentially diagnosing colon adenoma.

    abstract:BACKGROUND AND STUDY AIMS:Conventional colonoscopy can result in unnecessary biopsy or endoscopic resection due to its inability to distinguish adenomas from hyperplastic polyps. This study therefore evaluated the efficacy of high-resolution endoscopy (HRE), autofluorescence imaging (AFI), and narrow-band imaging (NBI)...


    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Sato R,Fujiya M,Watari J,Ueno N,Moriichi K,Kashima S,Maeda S,Ando K,Kawabata H,Sugiyama R,Nomura Y,Nata T,Itabashi K,Inaba Y,Okamoto K,Mizukami Y,Saitoh Y,Kohgo Y

    更新日期:2011-10-01 00:00:00

  • Prediction of rebleeding in peptic ulcers by visual stigmata and endoscopic Doppler ultrasound criteria.

    abstract::Following peptic ulcer hemorrhage, the ability to accurately determine those patients at highest risk of rebleeding relies on clinical and endoscopic criteria which are accurate in only a variable proportion of cases. In this study we have assessed prediction of rebleeding in peptic ulcers using a transendoscopic vasc...


    pub_type: 杂志文章


    authors: Fullarton GM,Murray WR

    更新日期:1990-03-01 00:00:00

  • Endoscopic ultrasonography: a promising method for assessing the prospects of endoscopic mucosal resection in early gastric cancer.

    abstract:BACKGROUND AND STUDY AIMS:A recent challenge that is increasingly being faced in endoscopy is the use of endoscopic mucosal resection (EMR) to treat differentiated intramucosal gastric cancers smaller than 2 cm. The usefulness of pretherapeutic endoscopic ultrasonography (EUS) in assessing whether this form of treatmen...


    pub_type: 杂志文章


    authors: Akahoshi K,Chijiiwa Y,Hamada S,Sasaki I,Maruoka A,Kabemura T,Nawata H

    更新日期:1997-09-01 00:00:00

  • Premedication for upper gastrointestinal endoscopy: a comparative study of flunitrazepam, diazepam and neuroleptanalgesia.

    abstract::Flunitrazepam or diazepam with atropine and a combination of phenoperidine, droperidol and cyclizine (neuroleptanalgesia) were compared as premedication in three groups of 25 patients undergoing routine upper gastrointestinal endoscopy. Drug doses were titrated carefully against response and all three regimes were fou...


    pub_type: 杂志文章


    authors: Nimmo WS,Forrest JA,Heading RC,Finlayson ND,Prescott LF

    更新日期:1978-08-01 00:00:00

  • Biliary Bezoar: the sump syndrome and choledochoenterostomy.

    abstract::The sump syndrome has been reported to occur infrequently following a choledochoenterostomy (duodenostomy or jejunostomy) for stone disease. The enterostomy stoma usually decreases in diameter following surgery allowing for reflux into the distal, inactive segment of the bile duct without adequate egress of the materi...


    pub_type: 杂志文章


    authors: Siegel JH

    更新日期:1982-11-01 00:00:00

  • Biliary manometry in swine: a unique endoscopic model for teaching and research.

    abstract::Biliary manometry, the "gold standard" for the diagnosis of sphincter of Oddi dysfunction, is associated with technical and methodological problems. The lack of a suitable experimental model has hindered efforts to solve these problems. We report here on the first practical animal model for endoscopic biliary manometr...


    pub_type: 杂志文章


    authors: Pasricha PJ,Tietjen TG,Kalloo AN

    更新日期:1995-01-01 00:00:00

  • The ultrasonically guided puncture of the gallbladder in amimals. A new methodological procedure for a simple and non-surgical collection of gallbladder bile.

    abstract::In 4 piglets the gallbladder was punctured under sonographic control threetimes during a period of 46 days. Each puncture was proved by X-ray controls after application of 2-4 ml of a water soluble contrast medium. One day after the third puncture all animals were killed in order to look for macroscopic or microscopic...


    pub_type: 杂志文章


    authors: Klapdor R,Scherer K,Sepehr H,Klöppel G

    更新日期:1977-08-01 00:00:00

  • Needle-knife sphincterotomy guided by a biliary endoprosthesis in Billroth II gastrectomy patients.

    abstract:BACKGROUND AND STUDY AIMS:All available techniques for performing endoscopic sphincterotomy in Billroth II gastrectomy patients have their limitations, and no standard technique has emerged. A new technique, needle-knife sphincterotomy guided by a thin (7 Fr) biliary endoprosthesis, is described here that overcomes som...


    pub_type: 杂志文章


    authors: van Buuren HR,Boender J,Nix GA,van Blankenstein M

    更新日期:1995-03-01 00:00:00