当前位置： SCI文献检索 > INTERNATIONAL UROGYNECOLOGY JOURNAL期刊下所有文献 > Clinical and urodynamic evaluation of women referred with diabetes mellitus.

Clinical and urodynamic evaluation of women referred with diabetes mellitus.

Abstract：

INTRODUCTION AND HYPOTHESIS:We investigated the impact of diabetes mellitus (DM) on female lower urinary tract dysfunction. METHODS:We prospectively collected data of 1,640 consecutive diabetic women from the inpatient departments and outpatient clinics of urology, endocrinology, geriatrics, and nephrology in primary, secondary, and tertiary referral hospitals, rural healthcare stations, and nursing homes in Dujiangyan, China. Clinical histories were taken on an individualized basis depending on patient presentation. Urodynamics were performed in the enrolled female diabetic patients after excluding other causes of lower urinary tract dysfunction. Data on lower urinary tract symptoms and urodynamic parameters were analyzed. RESULTS:Ninety-three percent of diabetic women complained of lower urinary tract symptoms, and 88 % had positive urodynamic findings. Sixty-three percent presented with storage symptoms, 918 cases of which had detrusor overactivity, 787 impaired detrusor contractility, and 131 detrusor areflexia. Among the 918 patients with impaired detrusor contractility or detrusor areflexia, the mean first sensation of filling was 238.1 ml, with a mean maximum cystometric capacity of 624 ml, mean maximum flow rate of 9.6 ml/s, mean detrusor pressure at maximum flow rate of 32.4 cmH2O, and mean postvoid residual of 323 ml. Thirty-eight of 131 patients with detrusor areflexia had impaired renal function on blood chemistry test, and massive bilateral ureterohydronephrosis and "Christmas-tree-shaped" bladder in videourodynamic studies. On the whole, 95 % diabetic women had diabetic cystopathy. CONCLUSIONS:DM alters voiding patterns significantly, causing various lower urinary tract symptoms in a significant proportion of diabetic women. Diabetic cystopathy is a progressive condition with a spectrum of clinical symptoms and urodynamic findings. The prevalence of diabetic cystopathy is very high in Dujiangyan, China.

journal_name

Int Urogynecol J

journal_title

International urogynecology journal

authors

Changxiao H,Zhengyong Y,Shibing Y,Caiwen W,Yingchuan H,Wei H,Hanhui W,Dong L,Peng H,Jing L,Rui Z,Jia L,Hong S

doi

10.1007/s00192-014-2354-5

subject

Has Abstract

pub_date

2014-07-01 00:00:00

pages

979-83

issue

eissn

0937-3462

issn

1433-3023

journal_volume

pub_type

杂志文章

在线工具

Clinical and urodynamic evaluation of women referred with diabetes mellitus.