Binding of deoxyadenylate and deoxycytidylate antibodies to double-stranded DNA.

Abstract:

:Antibodies raised against deoxyadenylate and deoxycytidylate were found to react with double stranded DNA as assessed by highly sensitive avidin-biotin microELISA. The binding was specific as it was completely inhibited by the homologous hapten. The antibodies did not react with tRNA and rRNA. These antibodies were also shown to react with supercoiled and relaxed forms of pBR322 DNA as demonstrated by gel retardation assay.

authors

Vaishnav YN,Antony A

doi

10.1016/0006-291x(88)90658-4

subject

Has Abstract

pub_date

1988-07-15 00:00:00

pages

118-23

issue

1

eissn

0006-291X

issn

1090-2104

pii

0006-291X(88)90658-4

journal_volume

154

pub_type

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