Hashimoto's encephalopathy mimicking presenile dementia.

Abstract:

:Hashimoto's encephalopathy (HE), which carries kaleidoscopic clinical presentations, is easily misdiagnosed in clinical practice. Early diagnosis and prompt initiation of steroid therapy are associated with good prognosis. We describe a 50-year-old female patient who had subclinical hypothyroidism and who presented herself with gradual cognitive impairment, accompanied with auditory hallucination and delusion. Increased anti-thyroid antibodies titers were found in her serum and cerebrospinal fluid. The HE diagnosis was confirmed using the laboratory test for anti-thyroid antibodies along with the patient's clinical presentation. We treated her with steroid pulse therapy, and the results were favorable. We highlight this case to call for early diagnosis and prompt intervention of HE in clinical practice.

journal_name

Gen Hosp Psychiatry

authors

Goh KK,Chiu YH,Shen WW

doi

10.1016/j.genhosppsych.2014.01.006

subject

Has Abstract

pub_date

2014-05-01 00:00:00

pages

360.e9-11

issue

3

eissn

0163-8343

issn

1873-7714

pii

S0163-8343(14)00010-3

journal_volume

36

pub_type

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