Abstract:
:We present a simple, noninvasive, nondestructive all-purpose method for the quantitative evaluation of functional effects of xenobiotics with cultured cells and the work station for its routine, easy implementation. At present 1 to 150 cells growing in one to six dishes can be studied in parallel or otherwise at time intervals ranging from 10 s to 6 h or more, over periods of time ranging from a few tens of minutes to 3-4 days. Any aspect of cell physiological behavior can be studied (differentiation-dedifferentiation, migration, division, degeneration, death) without preliminary staining and/or fixation provided it results in optically visible changes.
journal_name
Cell Biol Toxicoljournal_title
Cell biology and toxicologyauthors
Lees D,Pugnère D,Castel A,Raux O,Travo Pdoi
10.1007/BF00755775subject
Has Abstractpub_date
1994-12-01 00:00:00pages
305-9issue
5-6eissn
0742-2091issn
1573-6822journal_volume
10pub_type
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journal_title:Cell biology and toxicology
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