An epitope recognised by inhibitory monoclonal antibodies that react with a 51 kilodalton merozoite surface antigen in Plasmodium falciparum.

Abstract:

:Monoclonal antibodies designated 8G10/48 and 9E3/48 raised against mature asexual blood stages of Plasmodium falciparum inhibit parasite growth in vitro. Both antibodies bind to an epitope which includes the linear sequence Ser Thr Asn Ser and which is present in a cDNA clone from a P. falciparum expression library. These antibodies recognise a glycosylated antigen of approximately 51 kDa which is located on the merozoite surface membrane.

journal_name

Mol Biochem Parasitol

authors

Epping RJ,Goldstone SD,Ingram LT,Upcroft JA,Ramasamy R,Cooper JA,Bushell GR,Geysen HM

doi

10.1016/0166-6851(88)90173-9

subject

Has Abstract

pub_date

1988-02-01 00:00:00

pages

1-10

issue

1

eissn

0166-6851

issn

1872-9428

pii

0166-6851(88)90173-9

journal_volume

28

pub_type

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