[Clinical study of 113 cases of malignant melanoma].

Abstract:

:Malignant Melanoma (MM) incidence rate is increasing faster than many other cancer at present time. Its epidemiological and clinical behavior varies within countries. We have studied 113 cases of cutaneous melanoma from 1982-1993, that represents until now the largest series of MM studied in Chile. Superficial Spreading Melanoma was the most common type of MM with 37.5% of total cases followed by Nodular Melanoma 31.2%. Acral Melanoma 22.1%, and Lentigo Malignant Melanoma with 7.8%. MM favored females with 60.2% (n = 68) and males constituted 39.8% (n = 45) of all cases. Median age at diagnosis was 54 years. Primary more frequent location for man was thorax (36.4%) and lower extremities for women (28.6%). Hemorrhage, ulceration and rapid growth of a previously pigmented lesion as the primary cause for first medical visit were associated with high level of invasion, generally over 2 mm. thick. Color change and pruritus were associated with lower level of invasion. Patients in stage I (78.3%) had 1.35 mm of median invasive thickness in the primary lesion and patients in stage II (15.7%) had 3.03 mm.

journal_name

Rev Med Chil

journal_title

Revista medica de Chile

authors

Cabrera R,Silva S,Díaz de Medina J,Hoell I,Guglielmetti A,Rohmann I

subject

Has Abstract

pub_date

1994-08-01 00:00:00

pages

900-6

issue

8

eissn

0034-9887

issn

0717-6163

journal_volume

122

pub_type

杂志文章
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  • [Enteral nutrition in severe ulcerative colitis. Digestive tolerance and nutritional efficiency].

    abstract:BACKGROUNDS AND AIMS:Total parenteral nutrition (TPN) has been traditionally used as an adjunctive therapy in severe ulcerative colitis patients. We performed a prospective study to ascertain the safety, nutritional efficiency, tolerance and costs of total enteral nutrition in this situation. METHODS:After 48 hours of...

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    authors: Klaassen J,Zapata R,Mella JG,Aguayo G,Alvarado D,Espinosa O,Maíz A,Zúñiga A,Quintana C

    更新日期:1998-08-01 00:00:00

  • [Physical activity and cognitive reserve as protective factors for attentional functioning in older people].

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  • [Association of the TCF7L2 (RS7903146) genotype with adiposity and metabolic markers in the Chilean adult population].

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  • [Intestinal tuberculosis: analysis of clinical cases and autopsy].

    abstract::Intestinal tuberculosis is rare compared to other forms of the disease. A review of the last 10 years in a General University hospital identified 21 cases diagnosed at autopsy and 8 during life. Most patients were males, older than 30 years of age, alcoholics and originating in southern Chile. Evidence of concomitant ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Fica A,Belletti J,Cruzat C,Rojas D,Montalva M

    更新日期:1991-10-01 00:00:00

  • [Vital prognosis in severe acute hepatic failure. Value of the quantitative indexes of evaluation].

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    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Andresen M,Dussaillant G,Dougnac A,Arrese M,Arriagada D,Carlos Glasinovic J,Villarroel L

    更新日期:1995-11-01 00:00:00

  • [Treatment of Hodgkin's disease. National Protocol of Antineoplastic Drugs: preliminary report].

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    doi:

    authors: Gutiérrez J,Osorio G,García H,Vacarezza R,Cao C

    更新日期:1991-01-01 00:00:00

  • [No association between insulin sensitivity and serum lipid levels in postmenopausal women].

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    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872007000500009

    authors: Zavalza AB,Grover FP,Mora JM,Centeno M,Anaya RP

    更新日期:2007-05-01 00:00:00

  • [Inactivation of tumor suppressor genes in uterine cervix carcinogenesis].

    abstract::The importance of inactivation of tumor suppressor genes in the development/progression of carcinomas of the uterine cervix is reviewed. It is well known that HPV-related oncogenes are strongly linked to cervical cancer. However, fewer studies have explored the occurrence of inactivation of tumor suppressor genes in t...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:

    authors: Chuaqui R,Cuello M,Emmert-Buck M

    更新日期:1999-12-01 00:00:00

  • [A national online survey applied to patients with celiac disease in Chile].

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    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:/S0034-98872011000700003

    authors: Espino A,Castillo L C,Guiraldes E,Santibáñez H,Miquel JF

    更新日期:2011-07-01 00:00:00

  • [Default mode network and Alzheimer's disease].

    abstract::Brain functioning is mainly intrinsic, not primarily reflexive. This is supported by the high energy requirements of the resting brain (20% of all the energy consumed) which only marginally increases with changes in brain activity. Modern neuroimaging and neurophysiological techniques have led to the discovery of the ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

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    authors: Vergara E F,Behrens MI

    更新日期:2013-03-01 00:00:00

  • [Preliminary results of laparoscopic video esophagomyotomy in patients with esophageal achalasia].

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    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Csendes A,Burdiles P,Korn O,Braghetto I,Díaz JC,Henríquez A

    更新日期:2001-10-01 00:00:00

  • [Airway tridimensional printing].

    abstract::Tridimensional printing is becoming relevant in medicine, specially in surgical and interventional specialties. We review the technical aspects and clinical application of airway tridimensional printing. Using this technique, simulation models for bronchoscopy and models for diagnostic and therapeutic procedures such ...

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    pub_type: 杂志文章,评审

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  • [Population policy of the government of Chile].

    abstract::This article reports verbatim the National Development Plan for 1978-1983, issued by the Office of the President of the Chilean Republic, and by the Office of National Planning. The document states that an increase in population would be desirable; however, action toward such goal is to be taken by individual couples...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors:

    更新日期:1979-06-01 00:00:00

  • [Molecular genetic study of a severe growth hormone deficiency in a Chilean family].

    abstract::The first and so far the only form of isolated growth hormone deficiency to accede to molecular genetic analysis is IGHD 1A, which has an autosomal recessive mode of inheritance. Several sizes of growth hormone gene deletions, ranging from 6.7 to 8.5 Kb are responsible for IGHD 1A. It has been reported that children w...

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    pub_type: 杂志文章

    doi:

    authors: Aguirre E,Benítez R,Youlton R,Carvallo P

    更新日期:1993-09-01 00:00:00

  • [Acquired hemophagocytic syndrome treated with HLH 94-04 chemotherapy protocol: Report of four cases].

    abstract::Hemophagocytic syndrome is a severe condition of excessive immune activation that has a high mortality in the absence of treatment. The syndrome is classified as primary if associated with congenital or hereditary problems, or secondary/acquired if associated with infectious, autoimmune or oncology diseases. We report...

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    authors: Beffermann C N,Pilcante S J,Ocqueteau T M,Sarmiento M M

    更新日期:2015-09-01 00:00:00

  • [Cerebral vasodilators].

    abstract::Cerebral vasodilators (CVD) account for 1.6% of the annual expenditure on drugs in Chile. Two kinds are typified: what we have called orthodox CVD and calcium-channel blockers. They have two main uses in neurology: firstly, in acute ischaemic stroke where orthodox CVD (buflomedil, codergocrine mesylate, and nicergolin...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:

    authors: Alvarez G,Vacarezza R

    更新日期:1990-07-01 00:00:00

  • [Automatic keyword retrieval from clinical texts: an application of natural language processing to massive data of Chilean suspected diagnosis].

    abstract:BACKGROUND:Free-text imposes a challenge in health data analysis since the lack of structure makes the extraction and integration of information difficult, particularly in the case of massive data. An appropriate machine-interpretation of electronic health records in Chile can unleash knowledge contained in large volum...

    journal_title:Revista medica de Chile

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    doi:10.4067/s0034-98872019001001229

    authors: Villena F,Dunstan J

    更新日期:2019-10-01 00:00:00

  • [Medical coverage of the disease that causes death and place of death in the sixth region of Chile from 1990 to 2003].

    abstract:BACKGROUND:The place of death has changed and coverage of medical attention at death varies according to the development level of countries. AIM:To assess the evolution of coverage of medical attention of the last disease and place of death as indicators of health care quality and development level, in the sixth regio...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872007000800010

    authors: Leiva H H,León K F

    更新日期:2007-08-01 00:00:00

  • [Ménétrier disease. Report of one case].

    abstract:BACKGROUND:Ménétrier disease is a rare disorder of the stomach, characterized by giant hypertrophic folds that usually involve the gastric body and fundus, associated to hypoalbuminemia due to serum protein loss across the gastric mucosa. We report a 55-years-old male presenting with abdominal pain, vomiting, weight lo...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

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    authors: Gompertz M,Montenegro C,Bufadel ME,Defilippi C,Castillo J,Morales C

    更新日期:2012-09-01 00:00:00

  • [Cardiotoxicity of anticancer therapies. Towards the implementation of cardio-oncology units].

    abstract::Recently, we have witnessed major improvements in cancer treatment. Early diagnosis and development of new therapies have reduced cancer-related mortality. However, these new therapies, along with greater patient survival, are associated with an increase in untoward effects, particularly in the cardiovascular system. ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:10.4067/s0034-98872018000100068

    authors: Hameau R,Gabrielli L,Garrido M,Guzmán AM,Retamal I,Vacarezza MJ,Greig D,Ocqueteau M,Sánchez C,Pizarro M,Corvalán A,Lavandero S,Castro PF,Martínez G

    更新日期:2018-01-01 00:00:00

  • [Ectopic or migrating spleen and supernumerary spleens: detection and identification with 99mTc, 51Cr and 113In radioisotopes].

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    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:

    authors: Etcheverry R,Allamand JP,Guzmán G,Robinson MI

    更新日期:1989-12-01 00:00:00

  • [The notion of decision making capacity in medical and legal practice].

    abstract:BACKGROUND:The relationship between patients and health professionals emphasizes deliberation and joint decision making, that derives in the informed consent. AIM:To evaluate decision making of patients in health care and to identify the notion of capacity for decision making, according to lawyers and physicians. MAT...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

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    authors: Bórquez E G,Raineri B G,Horwitz C N,Huepe O G

    更新日期:2007-09-01 00:00:00

  • [Intensive chemotherapy for Burkitt lymphoma in HIV positive patients].

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    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872015001200001

    authors: Puga L B,Bustamante K K,Molina E J,Andrade M A

    更新日期:2015-12-01 00:00:00

  • [Hematopoietic stem cell transplantation for patients with Wiskott-Aldrich syndrome].

    abstract:BACKGROUND:Wiskott-Aldrich syndrome (WAS) is an X linked congenital disease that presents as eczema, thrombocytopenia and immune deficiency. The only curative procedure for this illness is hematopoietic stem cell transplant (HSCT), preferably from a healthy HLA identical sibling donor. Cord blood is becoming an excelle...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872007000700013

    authors: Wietstruck P MA,Zúñiga C P,Talesnik G E,Méndez R C,Barriga C F

    更新日期:2007-07-01 00:00:00

  • [Hyperthyroxinemia and clinical euthyroidism. Report of one case].

    abstract::The association of hyperthyroxinemia and euthyroidism is frequent and characterized by high plasma thyroxin concentrations, normal TSH values and absence of clinical signs of hyperthyroidism. We report an asymptomatic 28 years old male presenting with a serum total plasma thyroxin of 18.5 micrograms/dl (N 6.1-12.5), a...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: López JM,Mosso L,Campino C

    更新日期:1999-02-01 00:00:00

  • [Clinical correlations and evoked potentials in 29 cases of definitive multiple sclerosis].

    abstract::Aiming to correlate the alterations in evoked potentials with the initial clinical manifestations of multiple sclerosis, 29 patients with the disease were studied and 19 were followed for a lapse ranging from 1 to 11 years. Visual evoked potentials were studied in all the patients and 51% were abnormal. Auditory evoke...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Ferrer S,Jiménez P,Mellado L,Thieck E

    更新日期:1993-10-01 00:00:00

  • [A historical view of cardiology in Chile 1930-1990].

    abstract::The most significant facts in the development of Chilean cardiology since 1930 are reviewed. The preeminence of great clinicians in the thirties was followed by the creation of Departments of Cardiology in University Hospitals. The emergence of powerful diagnostic tools and cardiac surgery allowed an accelerated devel...

    journal_title:Revista medica de Chile

    pub_type: 历史文章,杂志文章

    doi:

    authors: Noguera H

    更新日期:1990-10-01 00:00:00

  • [Renovascular hypertension and abdominal bruit in a case: has its interpretation modified technology?].

    abstract::A lateral abdominal bruit is considered an important finding for the detection of renovascular hypertension. However, the precision and accuracy of new techniques such as angiography, Doppler ultrasound and studies with radioisotopes have changed its value and clinical interpretation. We report a 75 years old woman wi...

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    doi:

    authors: Duclos J,Jouanne E,Opazo M

    更新日期:1997-11-01 00:00:00

  • [Are congenital malformations increasing? Comparative study of 2 periods: 1971-1977 and 1982-1991, in the maternity of the Clinical Hospital of the University of Chile].

    abstract::The aim of this work was to analyze the global incidence of congenital malformations at the Maternity of University of Chile Clinical Hospital in the periods between 1971 and 1977 and between 1982 and 1992. A significant and sustained increase in incidence was observed in the first period from 10.64 per 1000 born aliv...

    journal_title:Revista medica de Chile

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    doi:

    authors: Nazer Herrera J,Cifuentes L,Ruiz G

    更新日期:1993-09-01 00:00:00