Abstract：
:Women with unexplained recurrent pregnancy loss (RPL) represent a highly heterogeneous group of patients. Past studies have investigated systemic endocrine and immunologic mechanisms as potential causes for pregnancy loss in unexplained RPL, while exciting new work has focused on spermatozoal, embryonic, and endometrial characteristics to explain the regulation of implantation and subsequent pregnancy loss. In the clinical and research context, stratification of women with unexplained RPL according to whether they have a high probability of pathologic status will help select women who are most appropriate for further investigation and potential future treatment.
journal_name
Obstet Gynecol Clin North Amjournal_title
Obstetrics and gynecology clinics of North Americaauthors
Saravelos SH,Regan Ldoi
10.1016/j.ogc.2013.10.008subject
Has Abstractpub_date
2014-03-01 00:00:00pages
157-66issue
1eissn
0889-8545issn
1558-0474pii
S0889-8545(13)00095-8journal_volume
41pub_type
杂志文章,评审abstract：:Abnormal uterine bleeding in the reproductive age, that is, dysfunctional uterine bleeding, is a very common symptom encountered in office gynecology. The judicious use of hysteroscopy to manage this medical entity adds a new dimension in handling this often perplexing problem. This article focuses mainly on abnormal ...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章
doi：
更新日期：1988-03-01 00:00:00
abstract：:The term sickle cell disease (SSD) encompasses several different sickle hemoglobinopathies. The ability to predict the clinical course of SSD during pregnancy is difficult. This article examines pregnancy-associated complications in SSD and the management of sickle cell disorders in pregnant women. Outcomes have impro...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.ogc.2010.02.015
更新日期：2010-06-01 00:00:00
abstract：:The placenta can serve as a valuable source of information about maternal and fetal conditions during the pregnancy; however, the abilities to perform a preliminary gross examination and interpret a placental pathology report are variable among obstetricians. This article discusses the indications for placental submis...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.ogc.2019.10.007
更新日期：2020-03-01 00:00:00
abstract：:The use of fetal blood sampling has been advocated widely to improve the specificity of fetal heart rate monitoring, but it remains a clinically unpopular procedure. This article considers its physiologic rationale and evidence base. It includes descriptions of the technique with suggestions for improved clinical inte...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0889-8545(05)70104-2
更新日期：1999-12-01 00:00:00
abstract：:Women who use tobacco, alcohol and drugs during pregnancy are at increased risk of maternal and fetal morbidity. Universal screening using empirically validated approaches can improve identification of substance-using pregnant women and facilitate comprehensive assessment of treatment needs. There is strong evidence f...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.ogc.2014.03.001
更新日期：2014-06-01 00:00:00
abstract：:This article reviews the general approach for assessing teratogenic risks related to fetal exposure, concentrating on the specific patterns associated with anticonvulsant usage and maternal epilepsy. Major anomalies that might be detected prenatally are presented, as well as the patterns of minor anomalies (syndromes)...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1991-12-01 00:00:00
abstract：:Induction of labor continues to be one of the most commonly performed tasks in obstetrics. If trials like the National Institute of Child Health and Human Development's ARRIVE trial show that delivery for all women at 39 weeks provides a significant advantage in pregnancy outcomes, the number of women who require indu...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.ogc.2017.08.010
更新日期：2017-12-01 00:00:00
abstract：:Obstetric hemorrhage accounts for 5% all deliveries in the United States and accounts for high maternal morbidity and mortality. Many hemorrhages are secondary to uterine atony and are quickly ameliorated with appropriate uterotonic use. However, for a subset of cases, severe hemorrhage may require advanced resuscitat...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.ogc.2016.07.006
更新日期：2016-12-01 00:00:00
abstract：:Penile HPV infection and disease are very common in sexually active men, and may be manifest in many forms. Treatment of clinically detectable lesions is advisable not only to relieve symptoms but also to prevent the spread of HPV infection to new sexual partners. Treatment of subclinical disease is more controversial...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0889-8545(05)70281-3
更新日期：1996-12-01 00:00:00
abstract：:This article provides a focused review of the evidence for several complementary health approaches (ie, omega-3 fatty acids, folate, vitamin D, selenium, zinc, magnesium, B vitamins, physical activity, yoga) in the treatment of perinatal depression. There is evidence that some of these treatments may be reasonable to ...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.ogc.2018.04.002
更新日期：2018-09-01 00:00:00
abstract：:Contemporary management of HIV in pregnancy remains a moving target. With the development of newer antiretroviral agents with lower side-effect profiles and laboratory methods for detection and monitoring of HIV, considerable progress has been made. This review examines key concepts in the pathophysiology of HIV and p...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.ogc.2014.08.003
更新日期：2014-12-01 00:00:00
abstract：:This article details the indicators, techniques, and anticipated success rates of laser surgery for vulvar condylomas and neoplasias. The role of adjuvant 5-fluorouracil and interferon is also discussed. ...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1991-09-01 00:00:00
abstract：:The United States cesarean rate has risen from 5.5 per 100 deliveries in 1970 to 24.1 per 100 deliveries in 1986 according to the National Hospital Discharge Survey. Less than 10 per cent of mothers have a vaginal birth after a prior cesarean. Women spend an average of 5.0 days in the hospital for a cesarean delivery,...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章
doi：
更新日期：1988-12-01 00:00:00
abstract：:Post-traumatic stress disorder (PTSD) accompanies miscarriage, intrauterine fetal demise, and preterm birth. Levels of PTSD may be higher for women who experience acute, life-threatening events during labor and delivery. Severe maternal morbidities or near misses for maternal death disproportionately impact African Am...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.ogc.2020.04.004
更新日期：2020-09-01 00:00:00
abstract：:Major advances in treatment for epithelial ovarian cancer have occurred over the last decade, giving hope to patients and families. Surgery remains a cornerstone of therapy. In early-stage epithelial ovarian cancer, a meticulous staging procedure should be performed to aid in determining patients who require appropria...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0889-8545(05)70234-5
更新日期：2001-12-01 00:00:00
abstract：:Emergency contraception is used after unprotected sex, inadequately protected sex, or sexual assault to reduce the risk of pregnancy. Of emergency contraceptive methods available in the United States, the copper intrauterine device has the highest efficacy, followed by ulipristal acetate, levonorgestrel-containing eme...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.ogc.2015.08.003
更新日期：2015-12-01 00:00:00
abstract：:Seizures and intracranial hemorrhage are possible medical diseases that any obstetrician may encounter. This article reviews the cause, treatment, and medical management in pregnancy for seizures and intracranial hemorrhage, and how the two can overlap into preeclampsia or eclampsia. This article also highlights some ...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.ogc.2012.11.009
更新日期：2013-03-01 00:00:00
abstract：:Since its initial approval by the US Food and Drug Administration (FDA) 20 years ago for the treatment of strabismus, hemifacial spasm, and blepharospasm in adults, botulinum toxin (BTX) has become one of the most frequently requested products in cosmetic rejuvenation around the world. After years of clinical success ...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章
doi：10.1016/j.ogc.2010.10.002
更新日期：2010-12-01 00:00:00
abstract：:Hydatidiform moles are divided into two syndromes: those of complete and partial moles. Both forms are genetically, morphologically, and clinically distinct. Choriocarcinoma can be associated with the complete mole that has not been described for the partial syndrome. Residual trophoblastic disease, on the contrary, c...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1988-09-01 00:00:00
abstract：:This article evaluates the complicated scenario for physicians when they must advise pregnant oncology patients and their families. Included in this discussion are a review of literature that addresses both maternal and fetal rights and an analysis of metaphysical considerations unique to this situation. Additionally,...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0889-8545(05)70004-8
更新日期：1998-06-01 00:00:00
abstract：:This article reviews the key concepts regarding the counseling and management of cervical dysplasia and invasive cervical cancer diagnosed during pregnancy. Emphasis is placed on balancing the maternal and fetal well-being in collaboration with appropriate multidisciplinary teams. Information regarding appropriate dia...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.ogc.2005.08.007
更新日期：2005-12-01 00:00:00
abstract：:Diagnosis of endometriosis requires careful interpretation of objective surgical and pathologic findings in the context of the patient's clinical presentation. Clinical assessment helps to identify patients at high risk of endometriosis and selects those who warrant further testing. Determination of the serum level of...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0889-8545(05)70307-7
更新日期：1997-06-01 00:00:00
abstract：:Despite persisting controversy over shoulder dystocia prediction, prevention, and injury causation, the authors find considerable evidence in recent research in the field to recommend additional guidelines beyond the current American College of Obstetricians and Gynecologists and Royal College of Obstetricians and Gyn...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.ogc.2011.02.015
更新日期：2011-06-01 00:00:00
abstract：:Although the advent of broad-spectrum antibiotics has markedly improved the maternal outcomes of pneumonia complicating pregnancy, pneumonia remains a significant condition that may complicate pregnancy. This article has reviewed the inherent physiologic respiratory changes that accompany pregnancy and the common caus...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0889-8545(05)70217-5
更新日期：2001-09-01 00:00:00
abstract：:Tubal factor infertility accounts for a large portion of female factor infertility. The most prevalent cause of tubal factor infertility is pelvic inflammatory disease and acute salpingitis. The diagnosis of tubal occlusion can be established by a combination of clinical suspicion based on patient history and diagnost...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.ogc.2012.09.006
更新日期：2012-12-01 00:00:00
abstract：:All the existing data show that combination estrogen/progestogen therapy is mandatory if any replacement therapy is to be given to the woman over age 40. Sufficient evidence has indicated that estrogen alone is inadequate; progestogen must be given to prevent endometrial hyperplasia, lower the risk of breast cancer, a...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1987-03-01 00:00:00
abstract：:Breast enhancement through augmentation improves not only the woman's physical appearance but also contributes to her psychologic well-being. With the current emphasis placed on women's breasts in the media, it is not surprising that small-breasted women feel inadequate. Recent US Federal Drug Administration approval ...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0889-8545(03)00055-x
更新日期：2002-03-01 00:00:00
abstract：:Recent guidelines from multiple organizations stress screening initiation no earlier than the age of 21 years and increased screening intervals for women aged 21 to 29 years. Primary prevention with human papillomavirus vaccination has the potential to significantly affect the development of high-grade cervical lesion...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章
doi：10.1016/j.ogc.2013.02.007
更新日期：2013-06-01 00:00:00
abstract：:Except in special circumstances, therapeutic insemination with a husband's sample has a low success rate. Couples in whom oligozoospermia has been identified as the principal cause of infertility do not benefit from therapeutic insemination by husband. Because of this low success rate, intrauterine insemination to pro...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1987-12-01 00:00:00
abstract：:Puerperal inversion of the uterus is an unusual and potentially life-threatening event occurring in the third stage of labor, but when managed promptly and aggressively inversion can result in minimal maternal morbidity and mortality. Once the diagnosis of inversion is made, measures should be undertaken to manage and...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 历史文章,杂志文章,评审
doi：
更新日期：1995-06-01 00:00:00
