Abstract:
:A single method for the quantitative determinations of three active ingredients, phenylephrine hydrochloride, phenylpropanolamine hydrochloride, and brompheniramine maleate, and one inactive ingredient (sodium benzoate) in a commercial product for colds is reported. The method is based on paired ion high-pressure liquid chromatography using 1-heptanesulfonic acid as the counterion. It is accurate and precise. The relative standard deviations based on six readings are reported. This method is sensitive; less than 1 microgram of each ingredient can be assayed. The peak area of each ingredient is related to its concentration.
journal_name
J Pharm Scijournal_title
Journal of pharmaceutical sciencesauthors
Ghanekar AG,Das Gupta Vdoi
10.1002/jps.2600670643subject
Has Abstractpub_date
1978-06-01 00:00:00pages
873-4issue
6eissn
0022-3549issn
1520-6017pii
S0022-3549(15)42032-5journal_volume
67pub_type
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