Abstract:
:Several technical advances over the years have allowed microsurgery to be successful. However, thrombosis, particularly at the anastomosis site, remains a complication of microvascular surgery. Various preventive measures, including drugs, have been used to improve microvascular surgical anastomotic patency rates. The purpose of this article is to review the literature and the current status of topical antithrombotic agents. From this review along with laboratory investigations it is concluded that a combination of topical as well as systemic agents offers the best patency rates. However, the "ideal" antithrombotic agent is yet to be discovered and investigations need to be continued in order to improve or eliminate the complication of microvascular thrombosis. But the importance of atraumatic technique cannot be overemphasized.
journal_name
Microsurgeryjournal_title
Microsurgeryauthors
Das SK,Miller JHdoi
10.1002/micr.1920150905subject
Has Abstractpub_date
1994-01-01 00:00:00pages
630-2issue
9eissn
0738-1085issn
1098-2752journal_volume
15pub_type
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