Current status of topical antithrombotic agents in microvascular surgery.

Abstract:

:Several technical advances over the years have allowed microsurgery to be successful. However, thrombosis, particularly at the anastomosis site, remains a complication of microvascular surgery. Various preventive measures, including drugs, have been used to improve microvascular surgical anastomotic patency rates. The purpose of this article is to review the literature and the current status of topical antithrombotic agents. From this review along with laboratory investigations it is concluded that a combination of topical as well as systemic agents offers the best patency rates. However, the "ideal" antithrombotic agent is yet to be discovered and investigations need to be continued in order to improve or eliminate the complication of microvascular thrombosis. But the importance of atraumatic technique cannot be overemphasized.

journal_name

Microsurgery

journal_title

Microsurgery

authors

Das SK,Miller JH

doi

10.1002/micr.1920150905

subject

Has Abstract

pub_date

1994-01-01 00:00:00

pages

630-2

issue

9

eissn

0738-1085

issn

1098-2752

journal_volume

15

pub_type

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