Abstract：
BACKGROUND:Our objective was to evaluate the long-term benefit of R2/3 lymph node dissection compared with that of R1, even in node-negative cases. METHODS:We analyzed clinicopathologic data on 373 surgically treated patients with early gastric cancer and without microscopic nodal involvement. RESULTS:Five- and 10-year survival rates for patients treated with R2/3 gastrectomy were 97.3% and 95.4%, respectively. These values were significantly higher than the 90.1% and 81.1% noted for R1 gastrectomy (p < 0.01). Although no difference was found in morbidity and mortality, the incidence of death from a recurrence of the gastric cancer was significantly higher in patients treated with R1 gastrectomy than those with R2/3. Multivariate analysis with the Cox's proportional hazard model revealed patients' age and R2/3 gastrectomy to be independent prognostic factors in patients with node-negative early gastric cancer. CONCLUSIONS:These data show that prophylactic lymph node dissection can potentially prolong the survival time of patients with node-negative early gastric cancer by preventing a recurrence of the gastric cancer.
journal_name
Surgeryjournal_title
Surgeryauthors
Baba H,Maehara Y,Takeuchi H,Inutsuka S,Okuyama T,Adachi Y,Akazawa K,Sugimachi Kdoi
10.1016/s0039-6060(05)80080-7subject
Has Abstractpub_date
1995-02-01 00:00:00pages
165-9issue
2eissn
0039-6060issn
1532-7361pii
S0039-6060(05)80080-7journal_volume
117pub_type
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