Abstract:
:Nonprescription medications are relatively safe, but not risk-free and can lead to serious adverse events, particularly if used contrary to directions or without attention to depicted warnings. The question arises whether the information presented on the product label is readable and comprehensible to the average lay person. We examined the product labels of nonprescription medications for readability and comprehensibility characteristics using the Flesch-Kincaid method. The Flesch-Kincaid reading ease scores and grade level scores were derived. We further validated the grade level scores using the Gunning-Fog method. Qualitative assessment of select labels found severe deficiencies such as poor organization and inundation with technical terms. By quantitative assessment the average reading ease score of 40 nonprescription medication labels (including nonsteroidal anti-inflammatory agents, antacids, laxative preparations, anti-allergy medications, H-2 blockers, proton pump inhibitors, sleep aids, an antiasthmatic, and cough and cold remedies) was 38 ± 12. The average Flesch-Kincaid grade level score was 16 ± 5. All labels except one were at reading grade level greater than the eighth grade. The average grade level of education necessary to understand the material according to the Gunning-Fog method was 17 ± 5 and all labels were above the eighth grade reading level. Nonprescription medication labels are written in a language that is not comprehensible to the average member of the general public. There is a need for considerable improvement in the readability of these labels.
journal_name
Ren Failjournal_title
Renal failureauthors
Trivedi H,Trivedi A,Hannan MFdoi
10.3109/0886022X.2013.872571subject
Has Abstractpub_date
2014-04-01 00:00:00pages
473-7issue
3eissn
0886-022Xissn
1525-6049journal_volume
36pub_type
杂志文章相关文献
RENAL FAILURE文献大全abstract:OBJECTIVE:We investigate the mechanism of neutrophil/lymphocyte ratio (NLR) elevation, a useful prognostic marker in patients with cardiovascular diseases (CVDs). METHODS:In this clinical study, we retrospectively searched for factors associated with NLR elevation in cardiovascular outpatients. In animal experiments u...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1080/0886022X.2019.1597736
更新日期:2019-11-01 00:00:00
abstract::The hallmark of the professional is continued development and expanded expertise based on acquisition of new knowledge and refinement of clinical skills. Medical knowledge acquisition is a key component of professional development for fellows in training as well as practicing physicians. New medical knowledge may be a...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/08860220903474428
更新日期:2010-01-01 00:00:00
abstract::Idiopathic nephrotic syndrome (NS) associated with focal segmental glomerulosclerosis (FSGS) and severe renal function impairment is usually refractory to the conventional treatment and progresses to end-stage renal disease. Herein, we reported 10 patients with NS-FSGS who had initially had CCr 34 +/- 12 mL/min/1.73 m...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1081/jdi-120039520
更新日期:2004-05-01 00:00:00
abstract:OBJECTIVE:To investigate the prevalence and risk factors for chronic kidney disease (CKD) among community elderly population in Shanghai, China, in order to provide early diagnosis and treatment of CKD, and improve the quality of life for elderly people. METHODS:In all, 24,886 residents (≥65 years old) were selected f...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1080/0886022X.2016.1229987
更新日期:2016-11-01 00:00:00
abstract::Glycine has been shown to protect against cisplatin (CP) nephrotoxicity in rats and to enhance the in vitro expression of heat-shock protein (hsp) 70 in renal epithelial cells following sublethal heat shock. We hypothesized that the protective effect of glycine against CP nephrotoxicity may be due to an up-regulation ...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/08860229709026258
更新日期:1997-01-01 00:00:00
abstract:INTRODUCTION:End-stage renal disease is the most debilitating condition for patients with renal diseases. Cardiovascular disease is the leading cause of death in these patients. It has been shown that nitric oxide (NO) increases in renal failure and hemodialysis patients and could be correlated with cardiovascular dise...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2013.830225
更新日期:2014-02-01 00:00:00
abstract::Several studies have shown that hepatocyte growth factor (HGF) ameliorates chronic renal failure, but its mechanism of action is unclear. This study was designed to test the delivery of HGF in the PCI-neo vector, using the 5/6 nephrectomized rat as a model for chronic renal failure, and to confirm that this protective...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2013.867797
更新日期:2014-04-01 00:00:00
abstract::Ciprofloxacin has been associated with several side effects including interstitial nephritis and hemolytic anemia. The combination of both side effects is extremely rare. In this report, we describe a case of ciprofloxacin-induced interstitial nephritis and autoimmune hemolytic anemia. Hemolytic anemia improved after ...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1081/jdi-120022557
更新日期:2003-07-01 00:00:00
abstract::There are conflicting results in studies concerning the best marker for liver histopathological features of HCV infection in HD patients. We planned a prospective study to follow HCV viremia and laboratory parameters of HD patients and correlate these with clinic features and histopathological findings. We included 68...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1081/jdi-100108192
更新日期:2001-11-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to investigate the cancer incidence in patients with end-stage aristolochic acid nephropathy (AAN). METHODS:A total of 102 patients with end-stage AAN treated in our hospital between 2004 and 2013 were included in this study. The correlation of cancer incidence with age, gender...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2014.990347
更新日期:2015-03-01 00:00:00
abstract::The case records of 75 patients who had systemic lupus erythematosus (SLE) and renal involvement on renal histology were reviewed. There were 70 females and 5 males, with a ratio of 14:1. The majority of the patients were in their second and third decades of life. SLE nephritis was distinctly uncommon in patients belo...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/08860229009066962
更新日期:1990-01-01 00:00:00
abstract::During exercise, the plasma urate levels and urinary excretion increase due to the enhanced purine degradation in skeletal muscle. Although urate transporter-1 (URAT1) is the main transporter responsible for the reabsorption of filtered urate, potential changes in its activity and expression during exercise have not b...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2010.494805
更新日期:2010-01-01 00:00:00
abstract::Injectable vitamin D agents are commonly used to manage secondary hyperparathyroidism in dialysis patients. Yet, there are few data documenting the trends and geographic variations in the use of these agents in large, representative samples. We sought to describe patterns and variations in the use of vitamin D formula...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2012.734260
更新日期:2013-01-01 00:00:00
abstract:PURPOSE:Mortality is a major problem in renal transplant patients, and appropriate preoperative evaluation is very important. We retrospectively reviewed the left ventricle ejection fraction (LVEF) of renal transplant patients. MATERIAL AND METHODS:The clinical records of 1763 patients who had preoperative LVEF result...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1080/0886022X.2016.1194162
更新日期:2016-11-01 00:00:00
abstract::The proximal convoluted tubule (PCT) is the major target for injury in gentamicin nephrotoxicity but the necrosis is often patchy and focal. The PCT is structurally, functionally, and metabolically heterogeneous, and the possibility of differential vulnerability to gentamicin-induced necrosis based on this heterogenei...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/08860229009087122
更新日期:1990-01-01 00:00:00
abstract::A 68-year-old male presented with acute myeloid leukemia, renal failure, hypokalemia, and enlarged kidneys on renal ultrasound. Renal biopsy revealed massive leukemic infiltration of the kidney. After systemic chemotherapy, the patient developed tumor lysis syndrome followed by a phase of proximal tubule dysfunction p...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1080/08860220902972187
更新日期:2009-01-01 00:00:00
abstract::Experimental perfusions of isolated rat kidneys were performed with flow rates adjusted to produce comparable glomerular filtration rates (GFR) in control and experimental groups. The experimental perfusate, consisting of Krebs-Ringer bicarbonate (KRB) containing 3.5% (uncrosslinked) stroma-free hemoglobin (SFH) plus ...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/08860229509037635
更新日期:1995-11-01 00:00:00
abstract:BACKGROUND:We aimed to evaluate whether serum apelin could reflect the nutritional status of children on dialysis. METHODS:Twelve patients on peritoneal dialysis (PD) and 20 patients on hemodialysis (HD) were enrolled. Patients received individualized diet for six months. Anthropometric and laboratory indices were mea...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2014.937661
更新日期:2014-09-01 00:00:00
abstract::Insidious progressive renal damage caused by type 1 diabetes mellitus (T1DM) begins in childhood before it becomes manifest in adult ages. Heat shock proteins (HSPs) regulate the cell response to any hazardous factors to prevent cell structure. The aim of the study is to determine whether urine levels of HSPs increase...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2015.1136893
更新日期:2016-01-01 00:00:00
abstract::This study was designed to evaluate the seroprevalence of hepatitis G virus (HGV) infection, its impact, and its relationship with other hepatotropic viruses among chronic renal failure patients undergoing hemodialysis at the Lok Nayak Hospital, New Delhi. The study group consisted of 100 consecutive cases of patients...
journal_title:Renal failure
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
abstract::Chronic kidney failure can be described as a chronic and progressive disfunction in metabolic-endocrine function and in adjustment of fluid-electrolyte balance of kidney, as a result of reducing of glomerular filtration value. Besides being a medical issue, chronic kidney failure affects social, economic, and psycholo...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2015.1006115
更新日期:2015-04-01 00:00:00
abstract:AIMS:The use of hemodialysis temporary dual-lumen catheters is often complicated by infections, which may be a significant cause of death among patients with end stage renal disease (ESRD). The aim of this study was to assess the incidence of bacteremia and bacterial colonization related to non-tunneled, non-cuffed, du...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1080/08860220701741940
更新日期:2008-01-01 00:00:00
abstract:UNLABELLED:Cardiovascular diseases are the major cause of morbidity and mortality in renal transplant recipients. We report our experience in the treatment of patients with renal allograft who required cardiovascular surgery. METHODS:Indications for cardiovascular surgery, postoperative complications, and outcome were...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2015.1052950
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:Despite the widespread availability of dialytic and intensive care unit technology, the probability of early mortality in critically ill patients with acute renal failure (ARF) is still high, and the evaluation of the patients' prognosis has been difficult. The Acute Physiology and Chronic Health Evaluation ...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1081/jdi-100001284
更新日期:2001-01-01 00:00:00
abstract::The concentrations of urea, creatinine, and uric acid were measured in edema fluid and plasma during hemodialysis and 18 h after hemodialysis. The concentrations of these solutes in plasma were 15-17% lower than in the edema fluid after hemodialysis. Eighteen hours after hemodialysis, however, the concentrations in pl...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/08860229209039118
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND:Crush syndrome developing as a result of earthquake and other natural disasters has been investigated from many angles to date. Data are scarce, however, on cases associated with the spontaneous crash of buildings. This study presents the results on seven rhabdomyolysis patients treated in our clinics out of...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1080/08860220701460095
更新日期:2007-01-01 00:00:00
abstract:AIM:Endoplasmic reticulum (ER) stress and unfolded protein response (UPR) are implicated in many fibrotic diseases, including renal fibrosis. Whether Ginsenoside-Rg1 (G-Rg1) could attenuate renal fibrosis via suppression of ER stress and UPR has not been reported. The aim of this study was to explore the effect of G-Rg...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2015.1015427
更新日期:2015-06-01 00:00:00
abstract::The case of giant renal cyst measuring 30 cm, accompanied by abdominal swelling and erythrocytosis, is presented. A 45-year-old male presented with large abdominal mass, atrophic left kidney, hypertension, and erythrocytosis. The patient underwent multiple preoperative phlebotomies, open extirpation of the cyst, and n...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2011.552148
更新日期:2011-01-01 00:00:00
abstract::Freshly isolated rabbit proximal tubules (PT), confluent primary rabbit proximal tubule cultures (PTC) and LLC-PK1 cells were characterised. Brushborder enzyme activities were lower in PTC than in LLC-PK1: ratios were 0.026 for alkaline phosphatase (AP), 0.458 for alanine aminopeptidase (AAP) and 0.514 for gamma-gluta...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/08860229009065561
更新日期:1990-01-01 00:00:00
abstract::Purine nucleotide liberation and their metabolic rate of interconversion may be important in the development of hypertension and its renal consequences. In the present study, blood triphosphate (ATP), adenosine diphosphate (ADP), and adenosine monophosphate (AMP) breakdown pathway was evaluated in relation to uric aci...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2014.882240
更新日期:2014-05-01 00:00:00