Abstract:
:Anaerobic bacteria outnumber aerobic bacteria in normal flora in the oropharynx and gastrointestinal tract. They are important and frequent causes of infection, although they often go unrecognized except in the classic and very distincitve clostridial infections and intoxications-gas gangrene, botulism, and tetanus. Although anaerobic infections often originate close to a muscosal surface where anaerobes are part of the normal flora, they may occur anywhere in the body via direct of hematogenous spread. Clues to diagnosis include a foul-smelling discharge, gas, necrotic tissue, abscess formation, the unique morphology of certain anaerobes on Gram's Stain, and failure to obtain growth on aerobic culture despite the presence of organisms on Gram-stained direct smear. Predisposing conditions include aspiration, vascular insufficiency, trauma, malignancy, and previous antimicrobial therapy. Clinical suspicion requires confirmation of diagnosis by appropriate collecting, transport and culturing of specimens while excluding contamination with anaerobes from the normal flora. Treatment usually requires a combination of surgical and medical measures. Penicillin G is the drug of choice for virtually all anaerobic infections except those caused by Bacteroides fragilis, which require chloramphenicol or clindamycin. Investigational agents also appear promising in the treatment of anaerobic infections.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Meyer RD,Finegold SMdoi
10.1097/00007611-197609000-00025subject
Has Abstractpub_date
1976-09-01 00:00:00pages
1178-95issue
9eissn
0038-4348issn
1541-8243journal_volume
69pub_type
杂志文章abstract::Coronary heart disease (CHD) is the leading cause of morbidity and mortality in patients more than 65 years old. Within this population, elevated cholesterol levels are prevalent and associated with increased risk of CHD. Despite increasing emphasis on lipid-lowering treatment in the elderly population, questions rema...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:
更新日期:2002-11-01 00:00:00
abstract::During the last 50 years, it has become evident that atherosclerosis originates in childhood. Although cardiovascular disease (CVD) events are rare in children, autopsy data and imaging studies have documented subclinical disease in association with measurable risk factors during childhood. When present at a young age...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000219
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVES:Age-related macular degeneration (AMD) is the leading cause of blindness in the United States. Although AMD shares multiple risk factors with coronary artery disease (CAD), the association between AMD and CAD has not been established. The objective of our study was to demonstrate an association between the d...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000329
更新日期:2015-08-01 00:00:00
abstract::We reviewed the results of lymphocyte karyotypes from 232 couples who had had two or more pregnancy losses (spontaneous abortions or stillbirths). Despite the use of strict criteria to correct for possible bias of ascertainment, 8% of these couples (19 of 232) had a chromosome abnormality. Six of these abnormalities w...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198812000-00014
更新日期:1988-12-01 00:00:00
abstract::Seventeen patients with Crohn's disease requiring emergency operative procedures disclosed important factors leading to successful outcome. In seven of the ten patients not known to have Crohn's disease, the history strongly suggested this diagnosis. Two patients died; three others had major complications, including t...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197810000-00010
更新日期:1978-10-01 00:00:00
abstract::Ten bites by Loxosceles reclusa, the North American brown recluse spider, are reported from South Carolina. Envenomation by the brown recluse spider is becoming a public health problem in the United States. The spider reportedly now is found from coast to coast in the southern half of the country and its range is prob...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197607000-00024
更新日期:1976-07-01 00:00:00
abstract::In 1954 I described a case of chronic fluoride poisoning from artificially fluoridated water, in which the patient exhibited a multisymptomatic clinical picture without noticeable skeletal changes. Subsequently, others and I have confirmed this "nonskeletal phase" of the disease from fluoride in water and in air (in w...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1980-03-01 00:00:00
abstract::In a patient with an asymptomatic left upper lobe pulmonary arteriovenous fistula, preoperative chest roentgenograms simulated bronchogenic carcinoma, but no overt feeding vessel was demonstrated. Intraoperatively no lesion could be palpated. Postoperative evaluation revealed a pulmonary arteriovenous fistula. This en...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198307000-00017
更新日期:1983-07-01 00:00:00
abstract::Giant cell arteritis has been thought to occur only in white patients. There have been several recent reports of this disorder to blacks, however, and this case of biopsy-proven giant cell arteritis in a black patient indicates the diagnosis should be considered in any elderly patient with typical symptoms regardless ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197909000-00045
更新日期:1979-09-01 00:00:00
abstract::Kleptomania, a disorder of impulse control in which the patients feel a compelling urge to steal objects of no value to them, has long been considered a disorder related in some fashion to sexual impulses. Recent advances in the clinical understanding of human sexual functioning have not been accompanied by an effort ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198708000-00015
更新日期:1987-08-01 00:00:00
abstract::The patient we have described had lower extremity numbness, paresthesias, constipation, urinary retention, and sexual dysfunction. Laboratory evaluation confirmed a diagnosis of acute intermittent porphyria (AIP). Vitamin B6 and glucose therapy initiated resolution of symptoms. The sensory neuropathy described here is...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1991-05-01 00:00:00
abstract::A case of pneumococcal endocarditis in an infant is reported together with a review of seven cases previously described in the literature. The prominent presenting symptoms of this usually fatal disease consisted of tachycardia, tachypnea, and cardiomegaly. A new murmur was heard in six of the eight patients. Fever wa...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197904000-00021
更新日期:1979-04-01 00:00:00
abstract::Variant angina pectoris, usually not precipitated by exertion or emotional stress, often is more severe and lasts longer than classic angina. The pain tends to recur at about the same time each day. Arrhythmias, usually ventricular, occur in about 50% of cases during the peak of pain. Electrocardiograms show a charact...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-197603000-00034
更新日期:1976-03-01 00:00:00
abstract::Lactulose is a poorly absorbed synthetic disaccharide frequently used in the treatment of portasystemic encephalopathy. Because lactulose syrup contains small amounts of absorbable sugars, it may cause hyperglycemia in diabetic individuals, but is usually well tolerated. We report the case of a patient with diet-contr...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199504000-00025
更新日期:1995-04-01 00:00:00
abstract::Thirty-four cases of meningococcal disease were identified in a retrospective survey of nine US Army posts in the southeastern United States from June 1977 to August 1979. Group B organisms predominated in dependents and civilian communities surrounding two of the posts, while active-duty personnel had a greater varie...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198102000-00007
更新日期:1981-02-01 00:00:00
abstract::Cladophialophora bantiana, a dematiaceous fungus, is an uncommon pathogenic organism originally thought to more commonly affect immunocompetent patients. Increasing numbers of reports, however, describe the organism affecting immunocompromised patients. Like all dematiaceous fungi, Cladophialophora can be recognized i...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/SMJ.0b013e318164e289
更新日期:2008-03-01 00:00:00
abstract::A phase II study of doxorubicin (Adriamycin)-based induction chemotherapy followed by cyclophosphamide/BCNU (CyBCNU) intensification and autologous bone marrow transplantation (ABMT) was conducted in 20 consecutive women with hormone-resistant metastatic breast cancer referred to our center. Of these 20 women, aged 24...
journal_title:Southern medical journal
pub_type: 临床试验,杂志文章
doi:10.1097/00007611-199503000-00015
更新日期:1995-03-01 00:00:00
abstract::Severe lactic acidosis is often associated with poor prognosis. Recognition and correction of the underlying process is the major step in the treatment of this serious condition. Intravenous administration of sodium bicarbonate has been the mainstay in the treatment of lactic acidosis. Aggressive use of this therapeut...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198107000-00018
更新日期:1981-07-01 00:00:00
abstract::Arsenic poisonings occur in Mississippi despite public education campaigns to prevent poisonings in the home. We reviewed 44 Mississippi cases of arsenic exposures occurring from January 1986 to May 1990. We compared the epidemiologic differences between unintentional and intentional poisonings. Cases were found and c...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199104000-00012
更新日期:1991-04-01 00:00:00
abstract::Each year an estimated 1.3 million Americans suffer eye injuries. There is little information in the literature regarding the prevalence, demographic characteristics, and prognosis of these patients. The Eye Injury Registry of Alabama (EIRA) serves as the first and only statewide system of its kind for the collection ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198707000-00004
更新日期:1987-07-01 00:00:00
abstract::Blastomyces dermatitidis, a dimorphic broad-based budding yeast endemic to the Mississippi River Valley region, is responsible for morbidity in humans via inhalation and dissemination. The response of acute lung injury, which produces an illness with serious morbidity and an approximately 50% mortality, uncommonly occ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199809000-00012
更新日期:1998-09-01 00:00:00
abstract::The use of psychotropic medication is often associated with weight gain. We provide documentation for this effect and review the mechanisms possibly responsible for it in the case of neuroleptic agents, lithium carbonate, monoamine oxidase inhibitors, and amitriptyline. We also enumerate the undesirable medical conseq...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198311000-00021
更新日期:1983-11-01 00:00:00
abstract::We reviewed our experience with thyroid sonography of 60 patients with nonfunctioning (cold) solitary thyroid nodules proven by iodine 123 scan. Twenty-two patients had surgery; the remaining 38 had thyroid scan and ultrasound only. In the first group, the echograms did not demonstrate the surgically proven nodules in...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198409000-00024
更新日期:1984-09-01 00:00:00
abstract:OBJECTIVE:This study compares the primary health care quality of community health centers (CHCs) and health maintenance organizations (HMOs) in South Carolina to elucidate the quality of CHC performance relative to mainstream settings such as the HMO. METHODS:Mail surveys were used to obtain data from 350 randomly sel...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.SMJ.0000066811.53167.2E
更新日期:2003-08-01 00:00:00
abstract::Psoriasis treatments range from topical treatments and phototherapy to oral systemic medications and injections. Despite good control of the disease when applying appropriate treatments (according to disease severity, insurance parameters, patient preference, and patients' ability to adhere), continued advancements wi...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.14423/SMJ.0000000000000596
更新日期:2017-01-01 00:00:00
abstract::We studied etiologic factors important in colonization of 179 central venous catheters (CVCs) in patients randomized into group 1 (who received daily topical applications of povidone-iodine) or group 2 (who received only dry dressing changes). Colonization rates of CVC tips were similar between group 1 (18/84 or 21%) ...
journal_title:Southern medical journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00007611-198404000-00012
更新日期:1984-04-01 00:00:00
abstract:OBJECTIVES:Cystic fibrosis (CF) is associated with vitamin D deficiency, which can lead to adverse effects including recurrent pulmonary infections and osteoporosis. We longitudinally investigated calcifediol or 25-hydroxyvitamin D (25(OH)D) levels for our pediatric patients with CF based on the time of year as well as...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000254
更新日期:2015-03-01 00:00:00
abstract::Early gradual ambulation is currently recommended for patients with acute low back pain if results of neurologic examination are normal. Bed rest for up to 2 days is considered optimal. To assess management practices, we retrospectively reviewed the medical records of individuals with acute back pain treated at three ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1991-05-01 00:00:00
abstract::We report the case of a 55-year-old woman who was thought to have systemic lupus erythematosus (SLE) for more than 13 years before Crohn's colitis was correctly diagnosed. The differentiation of Crohn's disease from SLE may be difficult, as illustrated by our case. Gastrointestinal symptoms, laboratory studies, and ra...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199510000-00018
更新日期:1995-10-01 00:00:00
abstract::Hepatobiliary tuberculosis (HTB) is uncommon and can be difficult to diagnose. We present our experience with HTB (over a 10-year period). Fourteen patients were identified from a total of 1888 cases of tuberculosis (TB) infection during this period. Five patients had isolated organ involvement [hepatic (n=3) and bili...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e318164ddbb
更新日期:2008-04-01 00:00:00