Abstract:
:Intracranial calcification (ICC) is a common finding on neuroimaging in paediatric neurology practice. In approximately half of all cases the calcification occurs in damaged, neoplastic, or malformed brain. For the large number of other disorders in which ICC occurs, no common pathogenetic mechanism can be suggested. Congenital infection, particularly with cytomegalovirus, accounts for a significant proportion of all cases. However, some genetic diseases, in particular Aicardi-Goutières syndrome, Band-like calcification, and RNASET2-related disease, may mimic congenital infection; therefore, a full consideration of the radiological and clinical features is necessary before concluding that congenital infection is the cause. In some disorders calcification is a universal finding, in others it is a frequent occurrence, and in some it is only an occasional finding. Characteristic patterns of calcification are seen in a number of conditions, and a systematic approach to the identification and description of radiological findings, taken together in the context of the clinical scenario, allows a diagnosis to be made in many cases. Nonetheless, there remain a number of presumed genetic disorders associated with ICC for which the underlying molecular cause has not yet been identified.
journal_name
Dev Med Child Neuroljournal_title
Developmental medicine and child neurologyauthors
Livingston JH,Stivaros S,Warren D,Crow YJdoi
10.1111/dmcn.12359subject
Has Abstractpub_date
2014-07-01 00:00:00pages
612-26issue
7eissn
0012-1622issn
1469-8749journal_volume
56pub_type
杂志文章,评审abstract::The aim of this study was to determine whether there are primary effects of prematurity on the development of explicit memory. Elicited imitation of action sequences was used to compare immediate and 15-minute delayed memory in term and preterm infants (19 months corrected age; n=48) who were at low risk: none had exp...
journal_title:Developmental medicine and child neurology
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journal_title:Developmental medicine and child neurology
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journal_title:Developmental medicine and child neurology
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journal_title:Developmental medicine and child neurology
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journal_title:Developmental medicine and child neurology
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journal_title:Developmental medicine and child neurology
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journal_title:Developmental medicine and child neurology
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doi:
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