Abstract：
:Pharmacologic labyrinthectomy has become an alternative to surgery for treatment of severe Ménièr's disease. The use of systemic streptomycin has been replaced by intratympanal instillations of gentamicin that are administered once daily for a limited number of days. Gentamicin provides a high success rate for ablation of vertigo without causing any unnecessary negative effects on hearing. Future development of more selective vestibulotoxic chemicals could mean that pharmacologic labyrinthectomy will become a simple and ultimate treatment for disabling Ménière's disease.
journal_name
Otolaryngol Clin North Amjournal_title
Otolaryngologic clinics of North Americaauthors
Hellström S,Odkvist Lsubject
Has Abstractpub_date
1994-04-01 00:00:00pages
307-15issue
2eissn
0030-6665issn
1557-8259journal_volume
27pub_type
杂志文章abstract：:The etiologies of otitis media with effusion are certainly multiple but remain incompletely understood. The treatment of otitis media with effusion varies considerably. A discussion of known facts as well as debated issues underlying these differences is presented. ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1987-05-01 00:00:00
abstract：:Over the years, a variety of empirical regimens have evolved using intratympanic gentamicin to treat the vertigo associated with Meniere's disease. Although these regimens have been effective, their application is not without risk. Many of the problems associated with intratympanic medications could be overcome with t...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1997-12-01 00:00:00
abstract：:The proper selection of allergen extracts is important in maintaining an efficient allergy practice. This article discusses pollen and mold spore selection, which may be relevant to an individual practitioner's testing survey. The selection of tree, grass, and weed pollen extracts depends on the location of the clinic...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0030-6665(03)00057-4
更新日期：2003-10-01 00:00:00
abstract：:The larynx is a highly vascularized organ supplied by the superior and inferior laryngeal arteries. Both microphonosurgery and external laryngeal surgery require excellent hemostasis. Topical agents including adrenalin and fibrin-based products as well as surgical instrumentation, such as coagulation devices or in som...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2016.03.009
更新日期：2016-06-01 00:00:00
abstract：:Partially implantable electromagnetic hearing aids have several potential advantages over conventional hearing aids. As conventional hearing aids improve in the quality of sound they deliver, however, the role of implant aids must be redefined. One area where they may provide the most benefit is in patients with moder...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1995-02-01 00:00:00
abstract：:The main issue in the management of glottic squamous cell carcinoma, as for all cancers, is adequate disease control while optimizing functional outcomes and minimizing morbidity. This is true for early-stage disease as for advanced tumors. This article evaluates the current evidence for the diagnostic and pretherapeu...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2012.06.014
更新日期：2012-10-01 00:00:00
abstract：:This presentation discusses the most valuable way to correlate specific morphologic changes in cochlear otospongiosis with sensorineural hearing loss. Both biochemical and vascular factors may be responsible for the association of far advanced otospongiosis and histopathologic changes. An enzymatic concept of the dise...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1978-02-01 00:00:00
abstract：:Sources of trauma to the external auditory canal range from impaction of small foreign bodies to severely comminuted temporal bone fractures sustained after blunt or penetrating forces. This article provides an overview of commonly encountered injuries. The proposed systematic approach to evaluation and management is ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1996-10-01 00:00:00
abstract：:This article focuses on the rare and obscure complications of endoscopic sinus surgery. The majority of surgeons will not encounter these complications in their practice, but should be aware of their possibility. With knowledge of these rare complications, the surgeon can understand the possible avoidance as well as u...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2015.05.012
更新日期：2015-10-01 00:00:00
abstract：:Cochlear implantation has been called a modern miracle and has probably exceeded the expectations of even its most ardent early pioneers. The capabilities of the preprogrammed brain permits patients, within minutes of activation, to appreciate common sounds not heard for many years and within days and weeks to compreh...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：10.1016/s0030-6665(05)70341-8
更新日期：2001-04-01 00:00:00
abstract：:The lacrimal drainage system is a very important functional and anatomic assembly in the orbit and midface. For surgeons who intend to become involved in its repair or reconstruction, it is mandatory to understand the full range of anatomic, physiologic, and diagnostic considerations prior to embarking upon a surgical...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1988-02-01 00:00:00
abstract：:There are two undeniable attributes of radiotherapy: its value in controlling head and neck malignancies and the progressive damage it inflicts on all treated tissues. It is fortunate that over the past decade, we have developed techniques and treatments that counteract, at least in part, the negative effects of radio...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1995-10-01 00:00:00
abstract：:Together, these tests provide a full evaluation of vestibular function in infants and small children. If attention is paid to creating the appropriate testing environment, and interpretation of the tests takes into account the unique properties of the responses of infants and young children, this testing can provide a...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0030-6665(02)00062-2
更新日期：2002-08-01 00:00:00
abstract：:This article summarizes the current management of pediatric thyroid disease, with an emphasis on surgical management. Medical and surgical approaches to hyperthyroidism are reviewed as well as pathways for evaluation of nodules and malignancy. Differences between pediatric and adult thyroid management are highlighted....
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2019.06.009
更新日期：2019-10-01 00:00:00
abstract：:Chronic rhinosinusitis (CRS) is one of the most frequent otolaryngologic diseases encountered. The diagnosis of CRS is made by a wide variety of practitioners, including primary care physicians,physician extenders, pulmonologists, and otolaryngologists. Therefore, an accurate, efficient, and accessible method of makin...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/S0030-6665(03)00151-8
更新日期：2004-04-01 00:00:00
abstract：:Cancer of the ear is similar, in many respects, to cancer of other skin-covered parts of the body. The aggressive nature of malignancies involving the ear is often underestimated, resulting in initial undertreatment. Later, the price is paid when a much more extensive operation is required to exenterate the cancer. A ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1993-04-01 00:00:00
abstract：:The mechanism of development of rupture of the round window membrane appears to be an increase in pressure in the cerebrospinal fluid transmitted to the inner ear via the cochlear aqueduct. Two cases of rupture of the round window membrane in divers are described in detail. One diver had ruptures of both round window ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1978-02-01 00:00:00
abstract：:Diet hypersensitivity may be "allergic," that is, caused by some form of immunologic reaction, or nonallergic. The latter includes chemical pharmacologic, enzymatic, or dietary disorders. Food allergies may be immediate Gell and Coombs type I reactions (5%), or delayed "serum sickness" type reactions (95%). The latter...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1992-02-01 00:00:00
abstract：:The multidisciplinary requirements of skull base surgery have evolved over the last 25 years. The heterogeneity of tissue types in the cranium base gives rise to a diverse group of benign and malignant neoplasms with vastly different prognoses. This article reviews the distinct clinicopathologic features of some of th...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0030-6665(05)70363-7
更新日期：2001-12-01 00:00:00
abstract：:The controversy over whether altered development of orofacial structures arises purely from expression of genetic potential or is influenced by environmental factors is reviewed. Resolving this controversy will determine the need for early intervention to permit nasal respiration and for orthodontic treatment. ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1989-04-01 00:00:00
abstract：:Endolymphatic sac tumors (ELST) are slow-growing, locally aggressive, low-grade malignancies that originate from the epithelium of the endolymphatic duct and sac. ELST often present with sensorineural hearing loss, tinnitus, and vertigo, which may mimic Meniere disease. Large tumors may present with additional cranial...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2014.12.006
更新日期：2015-04-01 00:00:00
abstract：:Hearing loss produces a communication handicap which is not always predictable from audiometric results. Handicap questionnaires can be useful for identification of potential rehabilitation candidates. Hearing aids have been improved but cannot be expected to compensate for all the speech perception problems associate...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1984-11-01 00:00:00
abstract：:The Sewall-Boyden flap, as used to reconstruct a frontal recess after frontoethmoidectomy, is conceptually similar to the endoscopic Lothrop procedure for surgical access to the frontal sinus. The operative technique, indications, and philosophy are presented in this article. ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0030-6665(05)70303-0
更新日期：2001-02-01 00:00:00
abstract：:It is evident from the foregoing that the evaluation of such a common complaint as nasal obstruction can be extremely complex. If a thorough history and examination are undertaken, however, only a small number of these investigations (if any) may be required. In each individual, it is always worth considering possible...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1992-08-01 00:00:00
abstract：:The majority of recurrent thyroid carcinomas are histologically differentiated and readily diagnosed by light microscopy or immunohistochemical staining. Infrequently, recurrent carcinoma may be less differentiated than the index lesion, creating diagnostic challenges. Complicating issues include thyroid carcinomas th...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2008.08.001
更新日期：2008-12-01 00:00:00
abstract：:Endovascular techniques can be utilized in many common otolaryngologic conditions. Advancements in in these techniques including but not limited to better distal access catheters, new embolization materials and stents allows this to be a relatively safe and successful procedure. Here we highlighted a few related proce...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2016.03.005
更新日期：2016-06-01 00:00:00
abstract：:A laryngeal fracture should be suspected when there is hemoptysis and subcutaneous emphysema following blunt injury to the neck. Computed tomography of the neck should be used to define the extent of the injury. Cervical vertebral fractures and dislocations, perforation of the pharynx and esophagus, and vascular injur...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1984-02-01 00:00:00
abstract：:Laryngeal inflammation includes a broad spectrum of pathologies, from infectious processes that need to be managed as airway emergencies, to indolent diseases that mimic head and neck cancer. The importance of a thorough history cannot be emphasized enough as it is the most important step toward developing a different...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2007.11.012
更新日期：2008-04-01 00:00:00
abstract：:Inner ear medical therapy has been gaining increasing popularity during the last 2 decades. Despite the increased use of this therapy,basic questions regarding this type of treatment have not been answered. The authors have used a variety of sustained-release devices in the laboratory to begin to answer some of these ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2004.04.005
更新日期：2004-10-01 00:00:00
abstract：:Benign paroxysmal positional vertigo is a common condition that can be severely incapacitating. The causative mechanism is usually displaced dense particles (canaliths) in a semicircular canal. By means of canalith repositioning, these particles can be moved into the utricle and the symptoms completely resolved in a h...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1996-04-01 00:00:00
