Abstract：
:The efficacy of low dose chloroquine, characteristic pattern of relapse and the relapse rate in vivax malaria after high dose primaquine were investigated in 167 Thai patients. 87 patients were allocated at random to receive 300 mg, and 80 received 450 mg of chloroquine on the first day of admission. All patients in both groups showed a rapid response with comparable fever clearance times (27.3 vs. 26.1 h) and parasite clearance times (67.1 vs. 58.1 h). After recovery and clearance of parasitaemia, the patients were allocated at random (double blind) to receive 2 dosage regimens of primaquine, a daily dose of 15 mg or 22.5 mg for 14 d. Relapses in both groups occurred within 6 months; no patient relapsed beyond that period. The relapse rate in the primaquine 15 mg group was significantly higher than that in the 22.5 mg group (17.5% vs. 2.4%).
journal_name
Trans R Soc Trop Med Hygauthors
Bunnag D,Karbwang J,Thanavibul A,Chittamas S,Ratanapongse Y,Chalermrut K,Bangchang KN,Harinasuta Tdoi
10.1016/0035-9203(94)90305-0subject
Has Abstractpub_date
1994-03-01 00:00:00pages
218-9issue
2eissn
0035-9203issn
1878-3503journal_volume
88pub_type
临床试验,杂志文章,随机对照试验abstract：:From June to December 1985 273 cases of hepatitis and jaundice were diagnosed in Maun, northern Botswana. It was known before the outbreak that most adults were immune to hepatitis A virus, most had markers indicating past infection with hepatitis B virus (HBV), there was a mean prevalence of 13.6% (57/418) HBsAg carr...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(89)90731-1
更新日期：1989-01-01 00:00:00
abstract：:Lesions due to Mycobacterium ulcerans infection may have more synonyms and eponyms than any other disease. New diseases are named for the person who discovered them, from the place from which they were first described or some major clinical feature. 'Buruli ulcer', the name by which the disease is most frequently know...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 评论,杂志文章,评审
doi：10.1016/j.trstmh.2008.12.009
更新日期：2009-10-01 00:00:00
abstract：:Because background seroepidemiological data are required before nationwide vaccination against hepatitis B virus (HBV) is attempted, the rate of exposure to HBV was investigated in two high-risk Saudi groups: patients on haemodialysis and patients with congenital bleeding disorders. Although the HBsAg carrier rate was...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(89)90668-8
更新日期：1989-03-01 00:00:00
abstract：:In Malawi, where high levels of chloroquine resistance were shown using a modified 7-day in vivo test, amodiaquine and pyrimethamine-sulfadoxine were evaluated as alternative initial therapies for Plasmodium falciparum infections in children under 5 years old. Therapy success rates, judged by parasite clearance by day...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(87)90005-8
更新日期：1987-01-01 00:00:00
abstract：:A survey of enteric pathogens in 143 children with diarrhoea, 116 age-matched controls and 524 asymptomatic people of all ages in a commercial farming area was carried out over a period of one year. Giardia lamblia was detected in 34% of the cases, 29% of the controls and 23% of asymptomatic people of all ages. Variou...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(87)90403-2
更新日期：1987-01-01 00:00:00
abstract：:A man bitten by a large coral snake (Micrurus lemniscatus helleri) in the Amazon basin of Ecuador developed persistent excruciating pain in the bitten arm. On admission to hospital less than 30 min later, he had a polymorphonuclear leucocytosis, thrombocytopenia and mildly prolonged prothrombin time/partial thrombopla...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章,评审
doi：10.1016/j.trstmh.2008.03.026
更新日期：2008-11-01 00:00:00
abstract：:Schistosomiasis among pregnant women has been inadequately investigated. In order to determine the importance of Schistosoma mansoni in this subgroup, we conducted a cross-sectional survey of 972 women in Tanzania and investigated the prevalence of Schistosoma mansoni, hookworm and malaria and their associations with ...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/j.trstmh.2005.06.024
更新日期：2006-01-01 00:00:00
abstract：:Melioidosis has never been officially reported from Cambodia. Here we report two cases, a 58-year-old male (case 1) and a 49-year-old female (case 2) who presented with respiratory illnesses featuring multiple lung abscesses. The sputum culture of both patients, taken in the framework of a laboratory-based study on ae...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/S0035-9203(08)70007-5
更新日期：2008-12-01 00:00:00
abstract：:The health and human rights communities have much in common. Recently, the international community has begun to devote more attention to the right to the highest attainable standard of health ("the right to health"). Today, this human right presents health and human rights professionals with a range of new opportuniti...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 社论
doi：10.1016/j.trstmh.2006.03.001
更新日期：2006-07-01 00:00:00
abstract：:During February and March of 1998, 12 sudden deaths were reported among residents of a high-Andean community in Ecuador. All 12 fatalities were members of the same extended family and some had apparent exposure to sick guinea-pigs. Following an initial investigation by public health officials, an additional death was ...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/s0035-9203(00)90114-7
更新日期：2000-07-01 00:00:00
abstract：:The role of the mucosal immune response against Cryptosporidium has been suggested by studies on the therapeutic effects of hyperimmune colostrum. In order to study the intestinal response to this infection, we have developed a sandwich-type time-resolved immunofluorometric assay for the determination of anti-Cryptosp...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(93)90152-g
更新日期：1993-05-01 00:00:00
abstract：:The assessment of antimicrobial resistance among commensal bacteria is an indicator of the spread of antimicrobial resistance. Rapid screening methods for detection of antimicrobial-resistant faecal Escherichia coli directly on MacConkey plates have been successfully adopted but suffer from lack of standardisation. Th...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/j.trstmh.2005.06.027
更新日期：2006-02-01 00:00:00
abstract：:The results of epidemiological surveys and the follow-up of malaria endemicity are often difficult to compare due to the high frequency of low-density parasitaemia in semi-immune populations. Detecting malaria parasites is dependent on the conditions and methods of parasitological examination. A standardized method of...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(85)90329-3
更新日期：1985-01-01 00:00:00
abstract：:There is a lack of information on the disease burden due to Taenia solium taeniasis and its associated risk factors in pig farming communities throughout the world. The present study was conducted in a rural pig farming community of north India to estimate the prevalence of T. solium taeniasis and associated factors. ...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/j.trstmh.2007.04.019
更新日期：2007-12-01 00:00:00
abstract：BACKGROUND:Rio de Janeiro (RJ) has been of major importance for the epidemiology of dengue viruses (DENVs) in Brazil. After the DENV 1-4 introductions in 1986, 1990, 2000 and 2011, respectively, the state has suffered explosive epidemics. We aimed to describe laboratorial, epidemiological and clinical aspects due to th...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1093/trstmh/trv006
更新日期：2015-04-01 00:00:00
abstract：:We report the case of a Colombian immunosuppressed migrant hospitalized in France with fever, dry cough and altered general health. Results of blood culture and bronchoalveolar lavage led to the diagnosis of the first reported case of concomitant disseminated histoplasmosis and pulmonary coccidioidomycosis in an HIV-i...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/j.trstmh.2005.03.003
更新日期：2005-09-01 00:00:00
abstract：:On return from duty in North Solomons Province (including Bougainville Island), Papua New Guinea, 586 Australian Defence Force personnel received either primaquine (14-d) or tafenoquine (3-d) post-exposure malaria prophylaxis. Within 12 months, 6 of the 214 volunteers receiving primaquine and 7 of 378 receiving tafeno...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/s0035-9203(02)90351-2
更新日期：2002-11-01 00:00:00
abstract：:Tungiasis (jigger) is endemic in many impoverished communities in many parts of Brazil. Forty-seven individuals entering an endemic area were followed up for a period of six weeks and regularly examined for the presence of newly embedded sand fleas. At the end of the third week, the attack rate of Tunga penetrans infe...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/j.trstmh.2003.12.004
更新日期：2004-07-01 00:00:00
abstract：:This paper reports the isolation and characterization of a complementary deoxyribonucleic acid clone showing sequence homology with genes coding for the eukaryotic elongation factor 1 gamma (EF-1 gamma). The clone encodes an open reading frame of 404 amino acids corresponding to a deduced molecular mass of 46.2 kDa. D...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/s0035-9203(02)90050-7
更新日期：2002-04-01 00:00:00
abstract：:A large epidemic of urban yellow fever occurred in April and May 1987 in Oyo State, western Nigeria. The principal vector was Aedes aegypti, breeding in domestic water containers. The 1987 outbreak followed an epidemic of sylvatic yellow fever in eastern Nigeria the previous year, and probably resulted from introducti...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(89)90518-x
更新日期：1989-05-01 00:00:00
abstract：:Eighty-seven Egyptians with Schistosoma haematobium infection (current or past) and chronic dysuria seen at the Theodor Bilharz Research Institute outpatient urology clinic in Imbaba, Cairo, Egypt were investigated for Chlamydia trachomatis infection. Direct fluorescent antibody tests (DFAT) showed 30 urethral swabs (...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(93)90284-w
更新日期：1993-11-01 00:00:00
abstract：:An outbreak of typhoid due to multi-drug resistant Salmonella typhi is reported from Pondicherry, India. While the average prevalence of drug resistant strains in 1980-1988 had been 11.7%, it increased to 52% in 1989-1990. The majority of strains (80.8%) were resistant to chloramphenicol, streptomycin, tetracycline an...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(92)90573-u
更新日期：1992-03-01 00:00:00
abstract：:Observations on canine leishmaniasis in Morocco (clinical symptoms, diagnosis, evolution, haematology, development of serum proteins, pathology and histopathology) are reported from dogs examined during 1979/80. Special reference is made to infantile kala-azar and its increasing incidence. The public health importance...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(87)90217-3
更新日期：1987-01-01 00:00:00
abstract：:Evaluating the performance of well child clinics on adherence to recommended perinatal hepatitis B prevention programmes as well as assessing the outcome of infants living with hepatitis B surface antigen (HBsAg)-positive parents is important. A retrospective study was performed of 336 babies who had at least one HBsA...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/j.trstmh.2010.12.001
更新日期：2011-04-01 00:00:00
abstract：:We report two patients who presented with a long-lasting febrile illness associated with pancytopenia. Both of them had evidence of hypercellular marrow with haemophagocytosis. They were confirmed as having rickettsial infections by serology and had a rapid haematological recovery with anti-rickettsial antibiotics. We...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/j.trstmh.2009.04.003
更新日期：2009-09-01 00:00:00
abstract：:We describe here a method, potentially suitable for field applications, for semi-quantitative detection of Mycobacterium leprae antigens in skin scrapings, which are taken normally for smear microscopy. Thirty acid-fast bacilli-negative paucibacillary (PB) leprosy patients comprised the main study group; eight acid-fa...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/j.trstmh.2007.02.026
更新日期：2007-07-01 00:00:00
abstract：:Polymerase chain reaction (PCR) is now widely used in malaria research for analysis of field samples. However, little has been reported regarding loss of sensitivity due to field methodology. Therefore, studies were carried out in relation to blood sampling (anticoagulants, culture medium, filter paper), storage (temp...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章,多中心研究
doi：10.1016/s0035-9203(99)90177-3
更新日期：1999-01-01 00:00:00
abstract：:Naegleria australiensis was recently described as a new species of free-living amoeba pathogenic for mice. Infections of human brain by the free-living amoebae N. fowleri and Acanthamoeba spp. are well known. We here describe the clinicopathological features of experimental infection of the central nervous system of m...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(83)90212-2
更新日期：1983-01-01 00:00:00
abstract：:A modified nested polymerase chain reaction (PCR) method for detection of Plasmodium falciparum, P. vivax and P. malariae was combined with a simple blood collection and deoxyribonucleic acid (DNA) extraction method and evaluated in Malaysia. Finger-prick blood samples from 46 hospital patients and 120 individuals liv...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/s0035-9203(96)90302-8
更新日期：1996-09-01 00:00:00
abstract：:Community treatment with ivermectin was implemented in Opoa, French Polynesia from April 1991 to October 1993. All consenting inhabitants aged 3 years or more were treated with twice-yearly single doses of ivermectin, pregnant women excepted. A dosage of 100 microgram/kg was used for the 3 first treatments and then ab...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/s0035-9203(96)90439-3
更新日期：1996-11-01 00:00:00
