当前位置： SCI文献检索 > JOURNAL OF CLINICAL NURSING期刊下所有文献 > A single-item self-report medication adherence question predicts hospitalisation and death in patients with heart failure.

A single-item self-report medication adherence question predicts hospitalisation and death in patients with heart failure.

Abstract：

AIMS AND OBJECTIVES:To determine whether a single-item self-report medication adherence question predicts hospitalisation and death in patients with heart failure. BACKGROUND:Poor medication adherence is associated with increased morbidity and mortality. Having a simple means of identifying suboptimal medication adherence could help identify at-risk patients for interventions. DESIGN:We performed a prospective cohort study in 592 participants with heart failure within a four-site randomised trial. METHODS:Self-report medication adherence was assessed at baseline using a single-item question: 'Over the past seven days, how many times did you miss a dose of any of your heart medication?' Participants who reported no missing doses were defined as fully adherent, and those missing more than one dose were considered less than fully adherent. The primary outcome was combined all-cause hospitalisation or death over one year and the secondary endpoint was heart failure hospitalisation. Outcomes were assessed with blinded chart reviews, and heart failure outcomes were determined by a blinded adjudication committee. We used negative binomial regression to examine the relationship between medication adherence and outcomes. RESULTS:Fifty-two percent of participants were 52% male, mean age was 61 years, and 31% were of New York Heart Association class III/IV at enrolment; 72% of participants reported full adherence to their heart medicine at baseline. Participants with full medication adherence had a lower rate of all-cause hospitalisation and death (0·71 events/year) compared with those with any nonadherence (0·86 events/year): adjusted-for-site incidence rate ratio was 0·83, fully adjusted incidence rate ratio 0·68. Incidence rate ratios were similar for heart failure hospitalisations. CONCLUSION:A single medication adherence question at baseline predicts hospitalisation and death over one year in heart failure patients. RELEVANCE TO CLINICAL PRACTICE:Medication adherence is associated with all-cause and heart failure-related hospitalisation and death in heart failure. It is important for clinicians to assess patients' medication adherence on a regular basis at their clinical follow-ups.

journal_name

J Clin Nurs

journal_title

Journal of clinical nursing

authors

Wu JR,DeWalt DA,Baker DW,Schillinger D,Ruo B,Bibbins-Domingo K,Macabasco-O'Connell A,Holmes GM,Broucksou KA,Erman B,Hawk V,Cene CW,Jones CD,Pignone M

doi

10.1111/jocn.12471

subject

Has Abstract

pub_date

2014-09-01 00:00:00

pages

2554-64

issue

17-18

eissn

0962-1067

issn

1365-2702

journal_volume

pub_type

杂志文章

在线工具

A single-item self-report medication adherence question predicts hospitalisation and death in patients with heart failure.