Abstract：
OBJECTIVES:To define the profile of 24-hour uterine activity in normal pregnancy and to correlate contraction frequency with physical activity and emotional stress diaries. METHODS:One hundred nine low-risk pregnant women who delivered at term recorded uterine contractions for 24 hours twice weekly from 20-40 weeks' gestation using an ambulatory monitor and kept a physical activity and emotional stress diary. Contractions per hour were calculated for each hour of the day and week of gestation, and related to physical activity and emotional stress. RESULTS:We analyzed 71,683 hours. No contractions were recorded in 73% of the hours, and fewer than four contractions per hour occurred in 96%. Significant inter-individual variability was noted. Contractions increased markedly with gestational age: The 95th percentile was 1.3 contractions per hour at 21-24 weeks, 2.9 at 28-32 weeks, and 4.9 at 38-40 weeks. A strong clustering of contractions occurred at night, which became pronounced after 24 weeks (night:day ratio 2:1 at 28-32 weeks). To adjust for the effects of gestational age and time of day, contractions per hour were converted to gestation- and hour-specific percentiles ("contraction percentiles"). Rest was associated with a fall in contraction percentile by 1.25, whereas coitus increased the contraction percentile by 5.52 (P < .05). No changes were noted with emotional stress. CONCLUSIONS:This study provides normative contraction data in uncomplicated pregnancy. A strong diurnal rhythm is present from 24 weeks onward, with 67% of contractions occurring at night. Contractions per hour increase with gestational age but rarely exceed three per hour before term. Rest and sexual activity have small but measurable effects on contraction frequency.
journal_name
Obstet Gynecoljournal_title
Obstetrics and gynecologyauthors
Moore TR,Iams JD,Creasy RK,Burau KD,Davidson ALdoi
10.1097/00006250-199404000-00006subject
Has Abstractpub_date
1994-04-01 00:00:00pages
517-23issue
4eissn
0029-7844issn
1873-233Xjournal_volume
83pub_type
杂志文章abstract：:We examined the release in vitro of tumor necrosis factor-alpha (TNF-alpha) by peritoneal macrophages and peripheral blood monocytes following incubation with toxic shock syndrome toxin-1 (TSST-1). We obtained peritoneal macrophages from 22 women at laparoscopy and peripheral blood monocytes from four healthy women du...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1991-08-01 00:00:00
abstract：:Parturients with heavy vaginal colonization of group B streptococci were selected randomly to receive either penicillin or no antibiotic. A simple and fast latex agglutination test, applied in 8977 consecutive parturients, detected 412 women with heavy colonization with group B streptococcus, 199 of whom were eligible...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1989-04-01 00:00:00
abstract：:A study of the records of patients seen in a two-year period in a private gynecologic practice and a one-year period in the emergency department of a general hospital was prompted by the incidence of chest wall pain diagnosed as costochondral pain. The study revealed 76 women in the former practice and 156 men and wom...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1983-11-01 00:00:00
abstract：:The histories of 386 patients with untreated hydatidiform mole were reviewed to define the clinical aspects of accompanying theca lutein cysts. These cysts occurred in 102 patients (26.4%), with three patients experiencing cyst-related complications. Mean cyst size at diagnosis was 7.3 cm (3-20 cm), and did not correl...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1988-08-01 00:00:00
abstract：:In 1992, the Executive Council of the Association of American Medical Colleges recommended that a computerized application system be investigated. Under this system, the application package would include: 1) a standardized application form, 2) a personal statement, 3) a dean's letter, 4) transcripts, 5) a chairman's l...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0029-7844(94)00388-T
更新日期：1995-02-01 00:00:00
abstract：:Twenty patients with triplet pregnancies underwent continuous-wave Doppler ultrasound umbilical artery waveform studies as part of a multiple-pregnancy surveillance program. One or more infants was small for gestational age in nine of these triplet pregnancies. In all of these cases, at least one abnormal umbilical ar...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1990-05-01 00:00:00
abstract：OBJECTIVE:To examine the associations of maternal and child characteristics with early pregnancy maternal concentrations of testosterone, androstenedione, progesterone, 17-hydroxyprogesterone, and estradiol (E2). METHODS:We analyzed these hormones among 1,343 women with singleton pregnancies who donated serum samples ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0b013e3182342b7f
更新日期：2011-11-01 00:00:00
abstract：:The force (as distinct from pressure) between the fetal head and the maternal cervix during labor was measured for the first time in an attempt to improve the intrapartum prediction of progress in labor. The 50th percentile of the variables active pressure and active force and the mean uterine activity integral were c...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1990-04-01 00:00:00
abstract：:Since 1963 there have been 266 patients with cancer of the uterine fundus at the Medical University of South Carolina. Progestational agents were used to treat 54 but 10 received the drugs for less than 1 month. This report relates to the remaining 44. 34 were treated with Depo-Provera (medroxyprogesterone acetate)...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1974-07-01 00:00:00
abstract：OBJECTIVE:To estimate the incidence of surgical-site infection with use of chlorhexidine-alcohol compared with povidone-iodine among women undergoing cesarean deliveries. METHODS:This was a retrospective cohort review of 1,000 consecutive cases in women who underwent cesarean delivery over a 1-year interval. The prima...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/aog.0b013e31826f3bd9
更新日期：2012-11-01 00:00:00
abstract：:Vaginal hysterectomy for sterilization was performed on 115 patients. The Heaney technique was used by nine gynecologists, using lidocaine and adrenaline. The average age of patients was 32.2 years and average parity 3.2. Significant unsuspected pathology was found after surgery in 21 patients. One postoperative d...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1972-05-01 00:00:00
abstract：:Thirty-eight women with stage I epidermoid carcinoma of the vulva were studied retrospectively in an attempt to define the criteria for conservative therapy in early invasive vulvar cancer. Among the 38 women, 23 met the 6 criteria established for early invasive carcinoma of the vulva. In those 23 women, there were no...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1982-06-01 00:00:00
abstract：OBJECTIVE:To document the initial clinical diagnoses, determine the prevalence of urinary symptoms, and test for intravesical potassium sensitivity in gynecologic patients with chronic pelvic pain. METHODS:Gynecologists at three United States medical centers administered the Potassium Sensitivity Test to consecutive u...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(01)01366-7
更新日期：2001-07-01 00:00:00
abstract：:The diagnosis of a cervical ectopic pregnancy is often made intraoperatively in the presence of extensive hemorrhage during attempted evacuation. In some cases, hysterectomy has been the necessary treatment to control bleeding. We report two cases of cervical pregnancy detected by ultrasound. Before pregnancy terminat...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1990-11-01 00:00:00
abstract：OBJECTIVE:To investigate the association between advanced maternal age and adverse pregnancy outcomes and to compare the risks related to advanced maternal age with those related to smoking and being overweight or obese. METHODS:A population-based register study including all nulliparous women aged 25 years and older ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000000062
更新日期：2014-01-01 00:00:00
abstract：BACKGROUND:Human immunodeficiency virus (HIV) lipodystrophy syndrome consists of insulin resistance, hyperlipidemia, increased waist-to-hip ratios, and relative hyperandrogenemia, which resembles polycystic ovary syndrome. CASE:A 30-year-old HIV-positive multipara with lipodystrophy syndrome had an elevated level of s...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/01.AOG.0000121832.02536.c3
更新日期：2004-05-01 00:00:00
abstract：:Congenital heart block is an unusual cause of fetal bradycardia. Until recently, the diagnosis could be confirmed only by evaluation of the fetal cardiac electrical activity. Two cases are reported in which the diagnosis of atrio-ventricular (A-V) dissociation was confirmed in the antepartum period by real-time ultras...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1979-03-01 00:00:00
abstract：:One hundred and thirty-three subarachnoid phenol blocks were performed in 90 patients with intractable pain secondary to gynecologic cancer at the University of Iowa Hospitals in the period 1961 to 1975. Excellent to moderate pain relief was obtained in 77% of 117 evaluable blocks. Fifty-two percent of the blocks gave...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1976-09-01 00:00:00
abstract：:The serum concentration of prolactin and the presence of galactorrhea were evaluated systematically in a prospective study of the effect of medroxyprogesterone acetate (MPA) in polycystic ovary syndrome (PCO). In 21 patients, the diagnosis of PCO was made by laparoscopy. Three women presented with galactorrhea and inc...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1980-04-01 00:00:00
abstract：:Reported is a rare complication of radical hysterectomy and radiation therapy, recurrent streptococcal cellulitis. Two patients had 14 episodes over a nine-year period, characterized by high fever and systemic toxicity. The streptococcal cellulitis was atypical in its presentation and its causative organism. The rash ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1984-06-01 00:00:00
abstract：OBJECTIVE:To report labor, delivery, and neonatal outcomes in a cohort of women delivering neonates who had undergone fetoscopic neural tube defect repair. METHODS:We conducted a retrospective cohort study from April 2014 to January 2018. All patients met Management of Myelomeningocele Study eligibility criteria. We i...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000002577
更新日期：2018-06-01 00:00:00
abstract：:We report the first known case of Chediak-Higashi syndrome in human pregnancy. This rare autosomal recessive disorder is characterized by partial oculocutaneous albinism, decreased leukocyte chemotaxis, susceptibility to infection, and death in childhood. Pathognomonic giant cytoplasmic granules are postulated to be d...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1992-05-01 00:00:00
abstract：OBJECTIVE:To examine cigarette smoking as a risk factor for different types of epithelial ovarian cancer. METHODS:We used data from the Cancer and Steroid Hormone Study, a multicenter, population-based, case control investigation. Cases were 447 women aged 20-54 years with diagnoses of epithelial ovarian cancer. Contr...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,多中心研究
doi：10.1016/s0029-7844(99)00531-1
更新日期：2000-02-01 00:00:00
abstract：:The American College of Obstetricians and Gynecologists' Committee on Obstetric Practice acknowledges that the issue of nonobstetric surgery during pregnancy is an important concern for physicians who care for women. Because of the difficulty of conducting large-scale randomized clinical trials in this population, the...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000003174
更新日期：2019-04-01 00:00:00
abstract：OBJECTIVE:To evaluate the role of immediate cerclage removal versus retention in patients experiencing premature rupture of the membranes remote from term (PROM). METHODS:Thirty patients with prophylactic cerclage experiencing PROM at 24-32 weeks were managed expectantly after either immediate removal in 20 (67%) or r...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1994-11-01 00:00:00
abstract：:Conjoined twins occur with a frequency of 1/50,000--1/100,000 deliveries. The cephalothoracopagus variety is particularly rare. This paper presents a case report of cephalothoracopagus (Janiceps) twinning, with a detailed pathologic analysis, as well as an historical review and discussion of diagnostic modalities. ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1979-09-01 00:00:00
abstract：OBJECTIVE:To evaluate weekly stripping of membranes at term to determine its safety and effectiveness in reducing the incidence of prolonged and postterm pregnancies. METHODS:One hundred forty-two pregnant women with certain gestational dates were randomly selected to receive, starting at 38 weeks, either weekly strip...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0029-7844(96)00046-4
更新日期：1996-06-01 00:00:00
abstract：OBJECTIVE:To examine the effect of persistent occiput posterior position on neonatal outcome. METHODS:This is a retrospective cohort study of 31,392 term, cephalic, singleton births. Women with neonates born in persistent occiput posterior position at delivery were compared to those with occiput anterior position. Wom...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/01.AOG.0000206217.07883.a2
更新日期：2006-04-01 00:00:00
abstract：:Cellular immunity of the delayed type in women with intraepithelial carcinoma (carcinoma is situ) of the vulva was investigated by an in vitro assay of mitogen-induced lymphocyte transformations. Test results from 9 patients were compared to those of 23 age-matched control subjects. Lymphocyte transformation responses...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1978-09-01 00:00:00
abstract：OBJECTIVE:To evaluate the long-term outcome of patients with severe cervical intraepithelial neoplasia or squamous cell carcinoma in situ (CIN III) after cold-knife conization with clear margins. METHODS:A total of 4417 women (mean age 36, range 18-72 years) with histologically confirmed CIN III had cold-knife conizat...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(00)01174-1
更新日期：2001-03-01 00:00:00
