Abstract:
:In this study, juvenile catfish (Clarias gariepinus) were exposed to 2 mg/L Pb, 0.5 μg/L cypermethrin, or both for 96 h. Survival ranged from 100% in both treatments without cypermethrin, to 50% in fish exposed to cypermethrin only or the mixture. There were significant decreases in liver lysozyme, γ-glutamyl transpeptidase, and alanine aminotransferase activities in fish exposed to cypermethrin or the mixture. Liver aspartate aminotransferase activity (AST) showed a significant reduction after exposure to Pb or cypermethrin alone, and the effect of the mixture on AST was additive or potentially synergistic. Liver lipid peroxidation (LPO) was increased in fish exposed to the mixture compared to those exposed to cypermethrin only, indicating that Pb presence enhanced LPO caused by cypermethrin. Our study demonstrates the potential for toxic interaction between Pb and cypermethrin in fish and suggests that due to the varying responses to contaminant mixtures in our study, researchers should consider using a variety of biomarkers.
journal_name
Bull Environ Contam Toxicoljournal_title
Bulletin of environmental contamination and toxicologyauthors
Adeyemi JA,Adewale OO,Oguma AYdoi
10.1007/s00128-013-1169-2subject
Has Abstractpub_date
2014-05-01 00:00:00pages
529-33issue
5eissn
0007-4861issn
1432-0800journal_volume
92pub_type
杂志文章abstract::Legislation such as the Stockholm Convention and REACH aim to identify and regulate the production and use of chemicals that qualify as persistent organic pollutants (POPs) and very persistent and very bioaccumulative (vPvB) chemicals, respectively. Recently, a series of studies on planetary boundary threats proposed ...
journal_title:Bulletin of environmental contamination and toxicology
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journal_title:Bulletin of environmental contamination and toxicology
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journal_title:Bulletin of environmental contamination and toxicology
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journal_title:Bulletin of environmental contamination and toxicology
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journal_title:Bulletin of environmental contamination and toxicology
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journal_title:Bulletin of environmental contamination and toxicology
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journal_title:Bulletin of environmental contamination and toxicology
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journal_title:Bulletin of environmental contamination and toxicology
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journal_title:Bulletin of environmental contamination and toxicology
pub_type: 杂志文章
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journal_title:Bulletin of environmental contamination and toxicology
pub_type: 杂志文章
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journal_title:Bulletin of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s00128-009-9867-5
更新日期:2010-01-01 00:00:00
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journal_title:Bulletin of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s00128-018-2376-7
更新日期:2018-09-01 00:00:00
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journal_title:Bulletin of environmental contamination and toxicology
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doi:10.1007/s00128-008-9557-8
更新日期:2008-12-01 00:00:00