Abstract:
:An integrated left ventricular (LV) model is used to solve, simultaneously and interactively, the LV mechanics, the coronary blood flow and capillary and interstitial fluid and mass transport, and to analyze the LV behavior under normal as well as pathological conditions. Accounting for the interstitial fluid mass balance in a LV flow-mechanical model allows to determine the LV wall volume in terms of the prevailing mechanical and flow conditions; it allows to uniquely define the flow-mechanical relationship and study pathologies, such as myocardial edema, which are directly related to changes in the myocardial fluid transport and content.
journal_name
Adv Exp Med Bioljournal_title
Advances in experimental medicine and biologyauthors
Zinemanas D,Beyar R,Sideman Sdoi
10.1007/978-1-4615-2946-0_21subject
Has Abstractpub_date
1993-01-01 00:00:00pages
219-31eissn
0065-2598issn
2214-8019journal_volume
346pub_type
杂志文章abstract::Administration of autoantigens, especially via the mucosal route, can induce tolerance under certain circumstances. In autoimmune diabetes, mucosal vaccination with autoantigens was frequently effective in restoring tolerance in mice but has not yet succeeded in humans. Furthermore, in some instances, autoimmunity can...
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