Ultrastructural observation of nerve fibers containing both substance P and calcitonin gene-related peptide in the nucleus tractus solitarii of the rat: a combination of immunofluorescence and PAP methods.

Abstract:

:Nerve fibers and their axon terminals with substance P (SP)-like and calcitonin gene-related peptide (CGRP)-like immunoreactivity in the nucleus tractus solitarii were ultrastructurally characterized by a combination of immunofluorescent double staining and the PAP method. The axon terminals formed asymmetrical synaptic contacts with other non-reactive neuronal elements (perikarya, dendritic shafts and dendritic spines). Some terminals received synaptic inputs from non-reactive axon terminals. This suggests that some, if not all, afferents containing SP and CGRP are affected presynaptically by other afferents.

journal_name

Brain Res

journal_title

Brain research

authors

Morishima Y,Takagi H,Kawai Y,Emson PC,Hillyard CJ,Girgis SI,MacIntyre I

doi

10.1016/0006-8993(86)90269-6

subject

Has Abstract

pub_date

1986-07-30 00:00:00

pages

157-61

issue

1

eissn

0006-8993

issn

1872-6240

pii

0006-8993(86)90269-6

journal_volume

379

pub_type

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