Abstract:
:We examined the effects of recombinant human tumor necrosis factor (rTNF) on highly metastatic rat prostatic cancer, Dunning R3327 MAT-LyLu, in vivo. It seemed that the inhibition of tumor growth needed more than 5 x 10(5) units of rTNF and this dose was near the lethal dose. Concerning the effect of rTNF on metastasis, we found that the metastasis to lung was promoted by 1 x 10(5) units of rTNF and the promotion of metastasis was restricted by indomethacin. Although MAT-LyLu cells were producing a significant amount of prostaglandin E2, rTNF did not enhance the production. We therefore consider that the promotion of metastasis was not mediated by prostaglandin E2 from MAT-LyLu cells but was mediated by other very complicated conditions. Further studies are necessary to resolve the mechanisms.
journal_name
Urol Intjournal_title
Urologia internationalisauthors
Iizumi T,Yazaki T,Umeda T,Soma GIdoi
10.1159/000282519subject
Has Abstractpub_date
1993-01-01 00:00:00pages
85-8issue
2eissn
0042-1138issn
1423-0399journal_volume
51pub_type
杂志文章abstract:BACKGROUND:No relevant data have been published on the impact of retroperitoneal lymph node dissection (LND) on clinical outcome in patients with castration-resistant prostate cancer. METHODS:We retrospectively studied the records of 6 patients with lymph node metastases from castration-resistant prostate cancer who u...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000335206
更新日期:2012-01-01 00:00:00
abstract:AIMS:To determine factors for treatment persistence in a real-life cohort of adult neurogenic lower urinary tract dysfunction. METHODS:We reviewed records of patients with neurogenic lower urinary tract dysfunction and mirabegron prescriptions. Exclusion criteria were indwelling urethral or suprapubic catheters and im...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000500349
更新日期:2019-01-01 00:00:00
abstract::Intrarenal blood flow distribution was measured in normal and hypoperfused dog kidneys by xenon-133 washout measurement in one kidney vary slightly in contrast to those done in different kidneys. In normal kidneys the ratio of compartment I (CI) flow to whole renal flow -- i.e., the CI fraction--as measured by the xen...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280818
更新日期:1982-01-01 00:00:00
abstract::We report the case of a woman who presented with obstruction and urosepsis of her left kidney secondary to small cystine calculi. The calculi could not be seen on initial plain abdominal X-ray. However, following percutaneous nephrostogram the calculi became more radio-dense and visible on later X-rays. Experimental e...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000030375
更新日期:1999-01-01 00:00:00
abstract::Adrenal cysts are very rare lesions, usually asymptomatic or without characteristic symptoms. They are classified as pseudocysts, endothelial cysts, epithelial cysts or parasitic cysts. Although pseudocysts are reported to be the most common clinically recognized adrenal cysts in surgical series, endothelial cysts are...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000111726
更新日期:2008-01-01 00:00:00
abstract::This study was undertaken to investigate the endocrine function of the testis that was autotransplanted by microvascular techniques in 10 healthy dogs. After a control period of 4 weeks, hemicastration was carried out, and 4 weeks later the experimental orchidopexy was done. Finally, the transplanted testis was remove...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280918
更新日期:1983-01-01 00:00:00
abstract:INTRODUCTION:Splenectomy had been previously performed in ABO-incompatible kidney transplantation to reduce the B cell pool. However, studies have shown that patients undergoing splenectomy may have a lifelong susceptibility to infection and mortality. Splenectomy may affect the incidence of cytomegalovirus (CMV) disea...
journal_title:Urologia internationalis
pub_type:
doi:10.1159/000504862
更新日期:2020-01-01 00:00:00
abstract::Idiopathic scrotal calcinosis is a rare, benign condition characterized by progressive calcification of the scrotal skin. A 29-year-old man who had undergone primary surgical excision of idiopathic scrotal calcinosis 7 years previously presented with recurrence that he had first noticed 3 years after surgery. Multiple...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000350240
更新日期:2014-01-01 00:00:00
abstract::Blind-ending bifid ureter in a woman with urinary tract infection and a duplicated renal pelvis in her twin sister are reported. The blind-ending bifid ureter terminated as a fibrous cord with a terminal mass of immature renal tissue. This type of ureter may be a transitional form between histologically blind-ending b...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280110
更新日期:1977-01-01 00:00:00
abstract:OBJECTIVES:In spite of a great amount of data, the hormonal treatment of advanced prostatic carcinoma (CaP) still remains controversial. As a relevant amount of dihydrotestosterone is present within the prostate tissue after castration, complete androgen blockade (CAB), with inhibition of the activity of both testicula...
journal_title:Urologia internationalis
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1159/000056541
更新日期:1998-01-01 00:00:00
abstract:INTRODUCTION:The goal of the study was to define treatment rules for the uncommon, rarely (10%) malignant and chemorefractory Leydig cell tumors (LCT) of the testis. METHODS:The main clinical data of patients treated in centers affiliated to the GUONE (North-Eastern Uro-Oncological Group, Italy) were reviewed. We cons...
journal_title:Urologia internationalis
pub_type: 杂志文章,多中心研究
doi:10.1159/000200790
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVE:To analyze the correlation between the genotypic and phenotypic patterns of p53 in patients with transitional cell carcinoma (TCC) of the urinary bladder. MATERIALS AND METHODS:Cross-sectional study of 73 patients diagnosed with TCC. DNA was obtained from the tumor tissue to perform polymerase chain reaction...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000109717
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:To describe our surgical experience and clinical outcome in laparoscopic radical nephrectomy (LRN) for renal cell carcinoma (RCC) with level 1 renal vein tumor thrombus. PATIENTS AND METHODS:11 patients with RCC level 1 renal vein tumor thrombus were treated by LRN plus thrombectomy. The mean age was 66.8 ye...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000363580
更新日期:2015-01-01 00:00:00
abstract:AIMS:To study the effects of left gonadal vein ligation on semen parameters and venous hemodynamics of the testis. SUBJECTS AND METHODS:All male voluntary kidney donors who were scheduled to have left donor nephrectomy between March 2004 and February 2005, by either open or laparoscopic technique, were considered for ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000277603
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Robotic-assisted laparoscopy (RAL) is being widely accepted in the field of urology as a replacement for conventional laparoscopy (CL). Nevertheless, the process of its integration in clinical routines has been rather spontaneous. OBJECTIVE:To determine the prevalence of robotic systems (RS) in urological c...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000430502
更新日期:2015-01-01 00:00:00
abstract:AIM:Papillary renal cell carcinoma type 1 (pRCC1) represents the second most common type of malignant renal epithelial tumour. The origin of its characteristic appearance, its growth mechanism, and the long-term efficiency of its surgical treatment remain uncertain. Our aim was to determine typical characteristics of s...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000448434
更新日期:2017-01-01 00:00:00
abstract::The purpose of this study is to evaluate the prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections and the related risk factors among urologic surgery patients and urologists. This cross-sectional, prospective study included 300 consecutive urologic surgery patients and 24 urologists working in ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000030330
更新日期:1998-01-01 00:00:00
abstract::We describe the 2 unique Asian cases of pure urinary bladder lymphoepithelioma-like carcinoma (LELCA). One patient had metastatic pelvic lymphoadenopathy and the other with superficial tumor. The EBER in situ hybridization both showed negative results despite racial or geographical factors might influence the peculiar...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000083565
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:Laparoscopic adrenalectomy is the gold standard for treatment of benign adrenal lesions. Tumor size is a factor that might influence decision-making concerning the use of laparoscopic approach. The aim of this study was to analyze the results of adrenalectomy for tumors ≥6 cm in diameter. METHODS:Two groups...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000444146
更新日期:2016-01-01 00:00:00
abstract::In 40 patients with urinary bladder tumours we compared the results of the immune profile, obtained by means of cutaneous tests with dinitrochlorobenzene (DNCB), and the infiltration of immunocompetent cells in the histological pattern after transurethral tumour resection. It was noted that the more the tumour had inf...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280798
更新日期:1982-01-01 00:00:00
abstract::A 25-year-old male with an incisional hernia following suprapubic trocar cystostomy for a failed traumatic perurethral catheterization is presented. This is only the 2nd case reported in the literature. Pathophysiology and management of this rare complication are discussed. ...
journal_title:Urologia internationalis
pub_type: 杂志文章,评审
doi:10.1159/000068764
更新日期:2003-01-01 00:00:00
abstract::Considerable progress has been made regarding pathogenesis, diagnosis and conservative management of urolithiasis. The cause of the disease can now be determined in nearly 80% of the patients. New stone formation may be prevented in the majority of patients by selective medical treatment. The metabolic, physicochemica...
journal_title:Urologia internationalis
pub_type: 杂志文章,评审
doi:10.1159/000281240
更新日期:1986-01-01 00:00:00
abstract::Myelolipomas are rare benign neoplasms of the adrenal glands, characterized by the presence of adipose tissue and elements of bone marrow in various degrees of differentiation. Usually asymptomatic, they are discovered incidentally or at autopsy; sometimes larger masses may cause local symptoms. We report clinical, ra...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282612
更新日期:1994-01-01 00:00:00
abstract::Nuclear Magnetic Resonance (NMR), a recently developed diagnostic method, has proved to be useful in the study of patients with prostatic disease. The authors report their experience with this technique in 10 cases of advanced prostate cancer (stage D) treated with LH-RH agonists (HOE 766-Buserelin). NMR provided info...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281218
更新日期:1986-01-01 00:00:00
abstract:AIM:The aim of this study was to compare the postoperative analgesic effectiveness of the 2 block types. We also aimed to evaluate the effect of these block types on the postoperative complications and parental satisfaction. MATERIALS AND METHODS:This prospective observational study was conducted between April and Jul...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000509173
更新日期:2020-01-01 00:00:00
abstract::To evaluate the degree of ischemic formation at the tissue level after high-energy shock wave (HESW) application in a time- and dose-dependent manner, an experimental study in rabbits was performed. Following varying numbers of HESWs (1,000-2,000-3,000 shock waves) under fluoroscopic localization, treated kidneys were...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282918
更新日期:1996-01-01 00:00:00
abstract:INTRODUCTION:Immunotherapy effectively treats advanced renal cell carcinoma in only a limited number of patients. However, the predicted prognosis for each patient in relation to immune status and response to immunotherapy remains problematic. We analyzed tumor-infiltrating lymphocyte (TIL) subsets to determine whether...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000064361
更新日期:2002-01-01 00:00:00
abstract:INTRODUCTION:No established technique for locating solitary carcinoma in situ (CIS) of the urinary bladder or CIS accompanying bladder cancer has been determined. Here we investigated whether the location of CIS of the urinary bladder can be macroscopically ascertained by instilling pirarubicin hydrochloride (THP) into...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000083555
更新日期:2005-01-01 00:00:00
abstract::It has been well established that erectile dysfunction (ED) is a common incident in patients with benign prostate hyperplasia. Animal models have been described to investigate the relationship between bladder obstruction and ED. In this study, we aimed to investigate whether partial bladder outlet obstruction (PBOO) i...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000137649
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVES:Our aim was to review our pathological archive to find out the actual incidence of micropapillary pattern (MPP) in our urothelial carcinoma patient population and determine its correlation with clinical outcome. PATIENTS AND METHODS:14 out of 170 cases with complete clinical follow-up were clinicopathologic...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000241672
更新日期:2009-01-01 00:00:00