A new antibacterial amino phenyl pyrrolidone derivative from a novel marine gliding bacterium Rapidithrix thailandica.

Abstract:

:A recently described marine gliding bacterium Rapidithrix thailandica strain TISTR 1741 was isolated from biofilm specimen collected from the Andaman Sea in Thailand. Four liters fermentation broth of R. thailandica TISTR 1741 cultivated in VY/2 medium were extracted with methanol to yield a novel amino phenyl pyrrolidone derivative compound (1) with antibacterial activities. The chemical structure and physico-chemical properties of 1 were investigated by spectrometry techniques. Compound 1 exhibited selective inhibition against vancomycin-resistant Enterococcus faecalis (VRE) with the MIC of 5.97 mM.

authors

Sangnoi Y,Plubrukarn A,Arunpairojana V,Kanjana-Opas A

doi

10.1007/s11274-013-1531-x

subject

Has Abstract

pub_date

2014-03-01 00:00:00

pages

1135-9

issue

3

eissn

0959-3993

issn

1573-0972

journal_volume

30

pub_type

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