Photosensitization with bacteriochlorins.

Abstract:

:Biophysical and photobiological properties of a group of bacteriochlorins were compared with efficacy of these products for photodynamic therapy of murine tumors. Predictive factors for selective photosensitization in vivo include affinity binding to lipoproteins greater than albumin, extinction coefficient at the wavelength of irradiation and tumor/skin distribution. Efficacy was correlated with circulating plasma levels of the different sensitizers but not with the photodynamic therapy response in cell culture.

journal_name

Photochem Photobiol

authors

Kessel D,Smith KM,Pandey RK,Shiau FY,Henderson B

doi

10.1111/j.1751-1097.1993.tb09549.x

subject

Has Abstract

pub_date

1993-08-01 00:00:00

pages

200-3

issue

2

eissn

0031-8655

issn

1751-1097

journal_volume

58

pub_type

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