Abstract:
:In 2004 was published the first edition of the "Surviving sepsis campaign" guidelines for the management of severe sepsis and septic shock, opening a new era in the treatment of this syndrome. The paradox is that guidelines application have produced positive results despite including in some cases treatments proven ineffective. Eight years later has been published the third edition of the guides, which updates the prior in the light of new knowledge, but the quality of evidence remains weak. In this paper the authors express their critical view on the current edition of the guides, pointing out their weaknesses and suggesting how the development of future editions should be.
journal_name
Med Intensivajournal_title
Medicina intensivaauthors
Palencia Herrejón E,Bueno García Bdoi
10.1016/j.medin.2013.07.008subject
Has Abstractpub_date
2013-12-01 00:00:00pages
600-4issue
9eissn
0210-5691issn
1578-6749pii
S0210-5691(13)00164-2journal_volume
37pub_type
杂志文章abstract::Brain death has been recognized by the scientific community as the person's death, and accepted in the legislation of different countries. Brain death is defined as the irreversible ending of the functions of all the intracranial neurological structure in both the brain and brain stem. This clinical situation appears ...
journal_title:Medicina intensiva
pub_type: 杂志文章,评审
doi:10.1016/s0210-5691(09)71215-x
更新日期:2009-05-01 00:00:00
abstract:OBJECTIVE:No data are available on blood caspase-8 concentrations (the initiator caspase in the extrinsic apoptosis pathway) in septic patients. The present study thus describes the blood caspase-8 concentrations in survivors and non-survivors, and examines the possible association between blood caspase-8 concentration...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/j.medin.2020.06.016
更新日期:2020-08-22 00:00:00
abstract::Recently, the work group made up of the National Transplant Organization (Organización Nacional de Trasplantes, ONT), Spanish Society of Intensive, Critical Medicine and Coronary Units (Sociedad Española de Medicina Intensiva, Crítica y de Unidades Coronarias, SEMICYUC) and other Scientific Societies have recommended ...
journal_title:Medicina intensiva
pub_type: 杂志文章,评审
doi:10.1016/s0210-5691(09)71760-7
更新日期:2009-06-01 00:00:00
abstract:OBJECTIVE:A comparison was made of the oxidative stress (OS) levels of patients with either viral or bacterial severe community-acquired pneumonia (sCAP) and of patients without infection (healthy volunteers (HV) and patients with acute myocardial infarction (AMI)). DESIGN:A prospective observational study was made. ...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/j.medin.2013.01.004
更新日期:2014-03-01 00:00:00
abstract:INTRODUCTION:Hemodynamic parameters such as the global end-diastolic volume index (GEDVI) and extravascular lung water index (EVLWI), derived by transpulmonary thermodilution, have gained increasing interest for guiding fluid therapy in critically ill patients. The proposed normal values (680-800ml/m(2) for GEDVI and 3...
journal_title:Medicina intensiva
pub_type: 杂志文章,meta分析
doi:10.1016/j.medin.2011.11.014
更新日期:2012-10-01 00:00:00
abstract::In 1994, an American-European Consensus Conference (AECC) formalized the criteria for the diagnosis of the acute respiratory distress syndrome (ARDS). Although that definition is simple to apply in the clinical setting, it has been challenged over the years in several studies since the assessment of the oxygenation de...
journal_title:Medicina intensiva
pub_type: 共识发展会议,杂志文章
doi:10.1016/j.medin.2012.08.010
更新日期:2012-11-01 00:00:00
abstract::The use of neuromuscular blockers (NMB) is a frequent practice in Intensive Care Units. However most of the experience with the use of these agents come from the operating room used to deal with patients with different characteristics from those admitted in the ICU. Recent advances on neuromonitoring and the commercia...
journal_title:Medicina intensiva
pub_type: 杂志文章,评审
doi:
更新日期:2008-02-01 00:00:00
abstract:OBJECTIVE:To evaluate different characteristics of patients with acute coronary syndrome (ACS) without ST-segment elevation compared with transient St-segment elevation. DESIGN:An observational, prospective study. SETTING:A 12-bed coronary care unit. PATIENTS:Consecutive patients of ACS without persistent ST-segment...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/j.medin.2011.01.007
更新日期:2011-06-01 00:00:00
abstract::Extracorporeal membrane oxygenation (ECMO) support is indicated in patients who are refractory to treatment, those with cardiogenic shock or respiratory failure and those with exacerbations eligible for heart and lung transplantation. Physician experience and quantity of necessary resources are reasons why regionaliza...
journal_title:Medicina intensiva
pub_type: 杂志文章,评审
doi:10.1016/j.medin.2018.01.004
更新日期:2019-03-01 00:00:00
abstract::We maintain a dynamic position on extracorporeal blood purification therapies (EBPT). Continuous therapies are of choice in the hemodynamically unstable patient. We recommend their early introduction in the course of the disease, and starting with a dose of 30-35mL/kg/h. Above all, however, daily re-evaluation is requ...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/j.medin.2016.05.009
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVE:To determine the clinical characteristics and prognostic factors of patients with severe sepsis/septic shock admitted to the Intensive Care Unit of Donostia University Hospital (Guipuzcoa, Spain). DESIGN:A prospective, observational study was carried out during a consecutive 6-year period (1st February 2008-...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/j.medin.2015.01.006
更新日期:2016-01-01 00:00:00
abstract::Tuberculosis miliar is a very rare complication of bacillus Calmette-Guérin (BCG) immunotherapy that is associated to high mortality. Thus, early diagnosis and treatment is essential. At present, there is a polymerase chain reaction technique (PCR) which is a rapid diagnostic method with elevated sensitivity. Treatmen...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/s0210-5691(06)74485-0
更新日期:2006-04-01 00:00:00
abstract:OBJECTIVE:To compare the results of quality monitoring after the implementation of improvement strategies in the respiratory intensive care unit (RICU). DESIGN:A prospective, comparative, longitudinal and interventional study was carried out. SETTING:The RICU of Hospital General de México (Mexico). PATIENTS:All pati...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/j.medin.2014.01.006
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVE:To describe the incidence and main clinical characteristics of barotrauma during open lung ventilation (OLV). DESIGN:A retrospective, observational, descriptive study was made of 100 patients with acute respiratory failure and bilateral pulmonary infiltrates. INTERVENTIONS:1) A lung recruitment maneuver (LR...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/j.medin.2011.10.011
更新日期:2012-06-01 00:00:00
abstract:OBJECTIVE:This article reviews the utility and applicability of available systems in order to calculate general and quality costs in clinical services settings. METHODS:Review of techniques to calculate costs in Intensive Care Units (ICUs) according to analytical accounting approaches. RESULTS:The methodological deve...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/s0210-5691(06)74498-9
更新日期:2006-05-01 00:00:00
abstract::Departments of Critical Care Medicine are characterized by high medical assistance costs and great complexity. Published recommendations on determining the needs of medical staff in the DCCM are based on low levels of evidence and attribute excessive significance to the structural/welfare approach (physician-to-beds r...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/j.medin.2017.09.013
更新日期:2018-01-01 00:00:00
abstract::Severe acute pancreatitis (SAP) causes local and systemic complications leading to high catabolic, hypermetabolic and hyperdynamic stress states with marked morbidity and mortality. In the last decade, nutritional support has become a key element in the treatment of SAP. Thus, specialized nutrition is indicated from a...
journal_title:Medicina intensiva
pub_type: 共识发展会议,杂志文章,实务指引
doi:10.1016/S0210-5691(11)70007-9
更新日期:2011-11-01 00:00:00
abstract::With the aim of analyzing the current state of the educational objectives in the training of medical residents in solid organ transplantation (SOT), we conducted a review of the status of the official programs of the specialities involved in SOT, focusing particularly on lung transplantation. A survey of medical resid...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/j.medin.2012.03.012
更新日期:2012-11-01 00:00:00
abstract::The utility of using quality indicators as a tool to measure the common practice and evaluate efficacy of measures established to improve quality has been demonstrated, making it possible to identify and make known the improvements carried out. The project "Quality indicators in the critical patient" has been conducte...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/s0210-5691(08)70899-4
更新日期:2008-01-01 00:00:00
abstract::Maintaining organ viability from extraction to transplantation is crucial to ensure the function and survival of the graft. In recent years, maintaining organ viability has become more challenging because the shortage of donors has led to broader criteria for donor acceptability and consequently to organs with greater...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/S0210-5691(09)72196-5
更新日期:2009-08-01 00:00:00
abstract:OBJECTIVE:An evaluation is made of the hospital mortality predicting capacity of the main predictive scoring systems. DESIGN:A 2-year retrospective cohort study was carried out. SETTING:A third level ICU with surgical and medical patients. PATIENTS:All patients with multiorgan failure during the first day in the ICU...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/j.medin.2015.03.005
更新日期:2016-04-01 00:00:00
abstract::This article is based on the strategic reflection and discussion that took place on occasion of the first conference on innovation and technology transfer in the health sciences organized by the REGIC-ENS-FENIN-SEMICYUC and held in Madrid in the Instituto de Salud Carlos III on May 7th, 2013, with the aim of promoting...
journal_title:Medicina intensiva
pub_type:
doi:10.1016/j.medin.2014.04.012
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND:The optimal blood management after cardiac surgery remains controversial. Moreover, blood transfusions may have an impact on long-term outcomes. OBJECTIVE:The aim of this study is to characterize the impact of liberal red blood cell transfusions on Health-Related Quality of life (HRQoL) after cardiac surger...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/j.medin.2018.01.014
更新日期:2019-04-01 00:00:00
abstract::There is a direct correlation between the development of the multiple organ dysfunction syndrome (MODS) and the elevated mortality associated with sepsis. The mechanisms responsible for MODS development are being studied, however, the main efforts regarding MODS evaluation have focused on oxygen delivery optimization ...
journal_title:Medicina intensiva
pub_type: 杂志文章,评审
doi:10.1016/j.medin.2008.10.002
更新日期:2009-11-01 00:00:00
abstract:PURPOSE:Streptococcus pneumoniae and Neisseria meningitidis are major causes of severe invasive bacterial infections in some individuals. Apparently the genetic is a major susceptibility determinant to these infectious diseases. We study if the functional polymorphisms within genes of the innate immune system (TLR2-TLR...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/j.medin.2013.08.006
更新日期:2014-08-01 00:00:00
abstract:OBJECTIVE:To design a probability model for prolonged mechanical ventilation (PMV) using variables obtained during the first 24 hours of the start of MV. DESIGN:An observational, prospective, multicenter cohort study. SCOPE:Thirteen Spanish medical-surgical intensive care units. PATIENTS:Adult patients requiring mec...
journal_title:Medicina intensiva
pub_type: 杂志文章,多中心研究
doi:10.1016/j.medin.2012.01.003
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:Before deciding increases in the number or capacitance of Intensive Care Units (ICUs), or the regionalization of Units, it is essential to know their present effectiveness. OBJECTIVE:To analyze the daily occupancy rate of ICUs in Catalonia (Spain) and the frequency of denied admission due to lack of capacit...
journal_title:Medicina intensiva
pub_type: 杂志文章,多中心研究
doi:10.1016/j.medin.2014.11.002
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVES:This study has aimed to establish the intensivist physician's concepts and practices in this region regarding the diagnosis, management and prevention of delirium in intensive care units (ICU). DESIGN:A survey was distributed among the FEPIMCTI member societies for distribution among its medical members. R...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/j.medin.2010.04.003
更新日期:2010-11-01 00:00:00
abstract::Second level therapeutic maneuvres for controlling intracranial hypertension (ICH) proposed by the European Brain Injury Consortium and the American Association of Neurological Surgeons include barbiturates, moderate hypothermia and more recently the decompressive craniectomy (DC).In most patients, ICP can be maintain...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/j.medin.2010.09.011
更新日期:2011-04-01 00:00:00
abstract:AIM:To determine the risk of microbiological contamination with hospital use high- and low-flow bubbling humidifiers. METHODS:A systematic literature review was carried out in 6 databases. Observational or experimental studies published between 1990 and 2016 were selected, written in English or Spanish, and in which m...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/j.medin.2017.11.003
更新日期:2019-01-01 00:00:00