Abstract:
:The intracavernosal pressure changes induced by 3 vasodilating drugs, diazoxide, glyceryltrinitrate and verapamil were investigated during autologous extracorporeal penile blood perfusion in an experimental rabbit model. In order to separate the arterial and venous components the experiments were performed with both intact and interrupted penile arterial inflow. The major hemodynamic effect of these drugs was an increased outflow resistance from the corpora cavernosa, probably effected through relaxation of the corporal smooth muscle. However, the intracorporeal pressure responses only reflected a part of the drug-induced smooth muscle relaxation. A theory is presented, according to which the corpora cavernosa are 'accumulating' smooth muscle relaxation, without direct reflection in an increased cavernosal pressure. At the moment when sufficient smooth muscle relaxation is achieved, a sudden increase in cavernosal pressure will appear and lead to an erection. This concept was generated through an approximation of corpora cavernosa to an elastic cylinder following the elastic law of Laplace in combination with the hydrodynamic law of Poiseuilles.
journal_name
Urol Intjournal_title
Urologia internationalisauthors
Lundbech PE,Kirkeby HJ,Djurhuus JCdoi
10.1159/000282454subject
Has Abstractpub_date
1993-01-01 00:00:00pages
65-70issue
2eissn
0042-1138issn
1423-0399journal_volume
50pub_type
杂志文章abstract:OBJECTIVE:This randomized controlled study compared a novel transparent urinary tract simulator with the traditional opaque urinary tract simulator as an aid for efficiently teaching urological surgical procedures. METHODS:Senior medical students were tested on their understanding of urological theory before and after...
journal_title:Urologia internationalis
pub_type: 杂志文章,随机对照试验
doi:10.1159/000375129
更新日期:2015-01-01 00:00:00
abstract:INTRODUCTION:Multiparametric MRI (mpMRI) and MRI targeted biopsies (MRtb) are a new standard in prostate cancer (PCa) screening and diagnosis. Guidelines already include this approach for patients at risk. We aimed to gather information from German urologists about their knowledge, routine use, and attitude toward mpMR...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000508755
更新日期:2020-01-01 00:00:00
abstract::Contractile responses of urinary bladder muscle strips to prostaglandin (PG) E1, E2 and F2 alpha were compared in young and old rabbits. All PGs tested caused an increase in contractile force of urinary bladder muscle strips from young (3 weeks) and old (greater than 2 years) rabbits. The contractile response was most...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281848
更新日期:1987-01-01 00:00:00
abstract::Characteristics of placental-like alkaline phosphatase (PLAP-like enzyme) in seminoma was studied. By use of lectin affinity chromatography, PLAP-like enzyme in seminoma revealed extra sugar chains compared to placental alkaline phosphatase (PLAP), indicating heterogeneity of the carbohydrate moiety. However, the glyc...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282263
更新日期:1991-01-01 00:00:00
abstract::Carcinoembryonic antigen (CEA) is elevated in urine and/or serum of patients with transitional cell carcinoma (TCC) of the urinary bladder. A group of 26 patients with TCC of the urinary bladder were evaluated with regard to urine/serum CEA levels and CEA tissue content. CEA could be detected in normal, metaplastic an...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280875
更新日期:1983-01-01 00:00:00
abstract:OBJECTIVES:The main purpose of the study was to identify and quantify clinical variables which predisposed incorrect diagnosis based on ultrasonography (US) and computed tomography (CT) findings in the patients with suppurative renal infections. PATIENTS AND METHODS:A retrospective review of radiological records of pa...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000132697
更新日期:2008-01-01 00:00:00
abstract:INTRODUCTION:Etiology of serum anti-p53 antibodies in bladder cancer patients is still unknown. In this study we evaluated the relationship between serum anti-p53 antibodies and microvessel density in bladder cancer patients. MATERIALS AND METHODS:Seventy-six patients with transitional cell carcinoma of the urinary bl...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000080831
更新日期:2004-01-01 00:00:00
abstract::Prostate volume in multiparametric MRI (mpMRI) is of clinical importance. For 3-Tesla mpMRI without endorectal coil, there is no distinctive standard for volume calculation. We tested the accuracy of the ellipsoid formula with planimetric volume measurements as reference and investigated the correlation of gland volum...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000448593
更新日期:2017-01-01 00:00:00
abstract::To our knowledge only a few cases of renal milk of calcium have been reported. We have encountered 5 such patients. The diagnosis depends upon the demonstration of half-moon-shaped calcification in the lateral decubitus or upright roentgenograms. This condition should be differentiated from a renal calculus to avoid u...
journal_title:Urologia internationalis
pub_type: 杂志文章,评审
doi:10.1159/000282538
更新日期:1993-01-01 00:00:00
abstract::Microwave surgery as a tool for improved prostatic electroresection is introduced. Prior to electroresection the prostate was coagulated with 2,450 MHz of microwave which was emitted from the bipolar electrode of a specially designed probe. We conducted a comparative study of 35 patients with bladder neck obstruction....
journal_title:Urologia internationalis
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000281870
更新日期:1987-01-01 00:00:00
abstract::The introduction in 1982 of vasoactive agents for intracavernous injection represents a milestone in the diagnosis and treatment of erectile dysfunction. Two preparations, the single drug papaverine hydrochloride and the combination of phentolamine mesylate and papaverine hydrochloride, hold great promise. In the last...
journal_title:Urologia internationalis
pub_type: 杂志文章,评审
doi:10.1159/000281308
更新日期:1988-01-01 00:00:00
abstract::We report the case of a 70-year-old man who received sunitinib treatment for brain metastatic clear cell renal cell carcinoma. After 6 months of treatment, brain MRI showed complete disappearance of two brain metastases. To the best of our knowledge, this is the first reported case of multifocal brain metastases in re...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000251193
更新日期:2009-01-01 00:00:00
abstract::During the past 10 years, buccal mucosa grafting for urethroplasty has gained widespread acceptance. In general the reported success rates are 80% and higher. Typical complications are recurrent strictures, fistula, and, especially when the technique of ventral onlay urethroplasty has been used, sacculations that are ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000096344
更新日期:2006-01-01 00:00:00
abstract::Inflammatory myofibroblastic tumors are commonly seen in young adults and adolescents and commonly present with painless hematuria. We report a case of a 38-year-old woman who presented to us with urinary retention due to a prolapsing tumor mass from the urethra, which was discovered to be an inflammatory myofibroblas...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000350516
更新日期:2014-01-01 00:00:00
abstract::The objective of the study was to evaluate possible changes of the gene expression and localization of the enzymes, heme oxygenase and nitric oxide synthase (NOS), with reference to increase of collagen type III in response to the partial obstruction of the bladder. Following initial obstruction, whole rat bladders we...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000099351
更新日期:2007-01-01 00:00:00
abstract::Modern LDR brachytherapy has drastically reduced rectal toxicity and decreased the occurrence of rectourethral fistulas to <0.5% of patients. Therefore, symptoms of late-onset sequelae are often ignored initially. These fistulas cause severe patient morbidity and require interdisciplinary treatment. We report on the o...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000209374
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVE:To explore the accurate Fas antigenic expression in transitional cell carcinoma (TCC) cells and and compare its synergistic modulation on adriamycin cytotoxicity with alpha-tumor necrosis factor (TNF-alpha). METHODS:The expression of Fas antigen in normal urothelium and TCC cell lines was measured by flow cy...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000068772
更新日期:2003-01-01 00:00:00
abstract:INTRODUCTION:Adherence to international guidelines is viewed as a prerequisite for optimal medical care delivery. Previously reported surveys for non-muscle-invasive bladder cancer (NMIBC) employed mailed questionnaires to urologists or patients resulting in conflicting degrees of agreement with existing guidelines. In...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000321926
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVES:Improvements in quality of life (QoL) and disease-related symptoms are key goals in the treatment of hormone refractory prostate cancer (HRPC). Our aim was to evaluate the impact of gefitinib on QoL of patients with HRPC. METHODS:Patients with HRPC received gefitinib 250 mg daily in addition to antiandrogen...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000200800
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to describe a novel negative-pressure laser lithotripsy device to overcome the deficiencies of the conventional procedure. PATIENTS AND METHODS:Between August 2018 and March 2019, 78 patients with a single ureteral stone underwent retrograde ureteroscopy with a Wolf 8F/9.8F rigid u...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000507266
更新日期:2020-01-01 00:00:00
abstract:INTRODUCTION:To evaluate the association between preoperative serum prolactin (PRL) levels and risk of non-organ confined prostate cancer (PCa) in clinically localized disease. MATERIALS AND METHODS:From December 2007 to December 2011, 124 patients with clinically localized PCa were retrospectively evaluated. Non-orga...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000496833
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Prostate cancer is a prominent form of cancer diagnosed in men living in developed countries, for which radical prostatectomy is a common frontline treatment. The aim of this systematic review was to determine whether robot-assisted laparoscopic radical prostatectomy (RALP) is more effective in the treatment...
journal_title:Urologia internationalis
pub_type: 杂志文章,评审
doi:10.1159/000435861
更新日期:2016-01-01 00:00:00
abstract::Between January 1985 and October 1991, 54 patients with calculi in a solitary kidney were treated by ESWL using the Dornier HM-3 lithotriptor. The mean age of the patients was 53.9 years (range 24-77 years). In 51.9% of the cases the stones measured > 1 cm in diameter, in 42.6% between 0.4 and 1 cm, and in 5.5% < 0.4 ...
journal_title:Urologia internationalis
pub_type: 杂志文章,评审
doi:10.1159/000282591
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVE:To describe our surgical experience and clinical outcome in laparoscopic radical nephrectomy (LRN) for renal cell carcinoma (RCC) with level 1 renal vein tumor thrombus. PATIENTS AND METHODS:11 patients with RCC level 1 renal vein tumor thrombus were treated by LRN plus thrombectomy. The mean age was 66.8 ye...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000363580
更新日期:2015-01-01 00:00:00
abstract::Proteus syndrome is a rare hamartomatous disorder comprising a broad spectrum of congenital malformations and overgrowth of multiple tissues. Some rare urogenital malformations have been reported before. This case is unique for the presence of multiple genitourinary anomalies including retroperitoneal cystic mass, int...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000089744
更新日期:2006-01-01 00:00:00
abstract::Laparoscopic partial nephrectomy (LPN) is increasingly becoming a definitive therapeutic option for the treatment of small (less than 4 cm) and select moderate-sized (less than 7 cm) renal tumors. Postoperative hemorrhage and urine leak are the most pertinent complications after nephron-sparing surgery, open or laparo...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000331905
更新日期:2011-01-01 00:00:00
abstract::The concept of resection of a solitary metastatic lesion is quite foreign in prostate cancer, as metastases to regional lymph nodes or to other distant sites are most likely suggestive of disseminated disease. The current report demonstrates a very unique case, in whom excision of a solitary pulmonary metastasis has r...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000109727
更新日期:2007-01-01 00:00:00
abstract:AIMS:The urodynamic findings and voiding habits in patients with concomitant clinical benign prostatic hyperplasia (BPH) and detrusor overactivity (DO) presenting with or without the symptom of urgency were compared. MATERIALS AND METHODS:84 BPH patients with an urodynamic diagnosis of DO by conventional cystometry we...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000099341
更新日期:2007-01-01 00:00:00
abstract:PURPOSE:To evaluate the association between dyslipidemia and nephrolithiasis risk in a Chinese population. MATERIALS AND METHODS:Fasting plasma lipid profiles were measured in a case-control study of 540 nephrolithiasis cases and 656 kidney stone-free controls. RESULTS:Triglycerides (TG) levels were significantly hig...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000496208
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To assess the association between the development of a urethral stricture (US) and disease-free survival for patients with localized prostate cancer treated with high-intensity focused ultrasound (HIFU). PATIENTS AND METHODS:Patients with clinical stage T1-T2N0M0 prostate cancer were eligible for treatment wit...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000330909
更新日期:2011-01-01 00:00:00