Abstract:
:The effect of 5-thio-D-glucose on the viability and radiosensitivity of P815-X2 mouse mastocytoma cells was studied in vitro. By itself, this compound is specifically cytotoxic toward hypoxic cells; moreover, it sensitizes hypoxic cells to irradiation while it protects aerobic cells from radiation damage. These features, together with its low toxicity, suggest that 5- thio-D-glucose may be useful adjuvant to radiotherapy
journal_name
Radiologyjournal_title
Radiologyauthors
Song CW,Clement JJ,Levitt SHdoi
10.1148/123.1.201subject
Has Abstractpub_date
1977-04-01 00:00:00pages
201-5issue
1eissn
0033-8419issn
1527-1315journal_volume
123pub_type
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