Effects of cannabis and familial loading on subcortical brain volumes in first-episode schizophrenia.

abstract：:The role of the brain-derived neurotrophic factor (BDNF) in the pathophysiology of major depressive disorder (MDD) remains to be elucidated. Recent post hoc analyses indicated a potential association of three polymorphisms in the BDNF gene with worse treatment outcome in patients with the subtype of melancholic depres...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Musil R,Zill P,Seemüller F,Bondy B,Obermeier M,Spellmann I,Bender W,Adli M,Heuser I,Zeiler J,Gaebel W,Maier W,Rietschel M,Rujescu D,Schennach R,Möller HJ,Riedel M

更新日期：2013-08-01 00:00:00

abstract：:Impairments in emotion recognition and psychosocial functioning are a robust phenomenon in schizophrenia and may affect motivational behavior, particularly during socio-emotional interactions. To characterize potential deficits and their interplay, we assessed social motivation covering various facets, such as implici...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Radke S,Pfersmann V,Derntl B

更新日期：2015-10-01 00:00:00

abstract：:Although classical and atypical antipsychotics may have different neurotoxic effects, their underlying mechanisms remain to be elucidated, especially regarding neuroglial function. In the present study, we compared the atypical antipsychotic risperidone (0.01-10 μM) with the typical antipsychotic haloperidol (0.01-10 ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Quincozes-Santos A,Bobermin LD,Tonial RP,Bambini-Junior V,Riesgo R,Gottfried C

更新日期：2010-09-01 00:00:00

abstract：:Three adult schizophrenic patients without a previous history of epilepsy are reported who, during clozapine treatment, developed paroxysmal EEG patterns and generalized myoclonic jerks without alteration of consciousness. These seizures were phenomenologically identical to those occurring in juvenile myoclonic epilep...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Gouzoulis E,Grunze H,von Bardeleben U

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVE:Interpersonal psychotherapy (IPT) is a time-limited psychotherapy for major depression. The aim of this study is to summarize findings from controlled trials of the efficacy of IPT in the treatment of depressive spectrum disorders (DSD) using a meta-analytic approach. METHODS:Studies of randomized clinical t...

journal_title：European archives of psychiatry and clinical neuroscience

authors： de Mello MF,de Jesus Mari J,Bacaltchuk J,Verdeli H,Neugebauer R

更新日期：2005-04-01 00:00:00

abstract：:The objective of this study is to determine whether cannabis influences BDNF levels in patients with psychosis (FEP) and healthy volunteers (HV) to help understand the role of BDNF in psychosis. We assessed the association between BDNF and cannabis in a cohort of FEP antipsychotic-naïve patients and HV, whilst control...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Toll A,Bergé D,Burling K,Scoriels L,Treen D,Monserrat C,Marmol F,Duran X,Jones PB,Pérez-Solà V,Fernandez-Egea E,Mané A

更新日期：2020-10-01 00:00:00

abstract：:The purpose of this study was to investigate the relationship between specific symptom severity and D2/3 receptor availability in extrastriatal regions in outpatients with schizophrenia to shed light on the role of extrastriatal dopaminergic neurotransmission in the pathophysiology of symptoms of schizophrenia. Sixtee...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Joo YH,Kim JH,Son YD,Kim HK,Shin YJ,Lee SY,Kim JH

更新日期：2018-09-01 00:00:00

abstract：:Negative symptoms were examined in 150 primarily first-admission patients diagnosed with schizophrenia, schizoaffective disorder, psychotic depression, psychotic bipolar disorder, and 'other' psychoses. The analysis focused on patients who were rated on the Scale for the Assessment of Negative Symptoms (SANS) within 4...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Fennig S,Bromet EJ,Galambos N,Putnam K

更新日期：1996-01-01 00:00:00

abstract：:To date, few studies have addressed the relationship between brain structure alterations and responses to atypical antipsychotics in schizophrenia. To this end, in this study, magnetic resonance imaging (MRI) and voxel-based morphometry (VBM) were used to assess the relationship between the brain volumes of gray (GM) ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Molina V,Martín C,Ballesteros A,de Herrera AG,Hernández-Tamames JA

更新日期：2011-09-01 00:00:00

abstract：:A follow-up and family study was carried out of 16 first episode, DSM-III-R schizophreniform disorder patients with good prognostic features. Mean length of follow-up was 52.3 months. It was found that 62.5% had affective episodes, 31.2% had schizophreniform episodes. No case of schizophrenia was observed. Outcome was...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Benazzi F,Mazzoli M,Rossi E

更新日期：1992-01-01 00:00:00

abstract：:Neurofunctional mechanisms underlying cognitive behavior therapy (CBT) are still not clearly understood. This functional magnetic resonance imaging (fMRI) study focused on changes in brain activation as a result of one-session CBT in patients suffering from spider phobia. Twenty-six female spider phobics and 25 non-ph...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Schienle A,Schäfer A,Hermann A,Rohrmann S,Vaitl D

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVE:This exploratory study aims to compare lifetime psychiatric axis-I-comorbidity and psychosocial functioning in a clinically referred sample of adult patients with attention-deficit/hyperactivity disorder (ADHD) with a population-based healthy control group and to examine whether patients with ADHD and lifetim...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Sobanski E,Brüggemann D,Alm B,Kern S,Deschner M,Schubert T,Philipsen A,Rietschel M

更新日期：2007-10-01 00:00:00

abstract：:Sustainable observations suggest that suicidal behaviour by itself may have biological correlates, among which those related to the serotonergic synapse hold the key position. Based on the association of suicide and serotonergic dysfunction, it was proposed that genetic mechanisms affecting suicidal behaviour could be...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Stefulj J,Büttner A,Kubat M,Zill P,Balija M,Eisenmenger W,Bondy B,Jernej B

更新日期：2004-08-01 00:00:00

abstract：:Minority religions, sects and cults are an increasingly common socio-cultural phenomenon, of which the effects concerning mental health and illness are still poorly understood. In the present study, we compared socio-demographical and clinical characteristics between members of Christian sects and the remaining genera...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Dalgalarrondo P,Lotz M

更新日期：1993-01-01 00:00:00

abstract：:Thirty inpatients with somatoform disorders were examined with the structured clinical interview SCID for psychiatric lifetime diagnosis. In the present diagnoses, we found a concordance of 63% for somatoform and affective disorders and the lifetime comorbidity of both disorders was 87%. Additionally, patients with so...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Rief W,Schaefer S,Hiller W,Fichter MM

更新日期：1992-01-01 00:00:00

abstract：:Cognitive impairment in psychosis is closely related to functional outcome, so research into psychotic disorders is focusing most effort on treatments for improving cognition. New treatments must show not only an improvement on neuropsychological tests but also in co-primary measures of cognition. The cognitive assess...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Sánchez-Torres AM,Elosúa MR,Lorente-Omeñaca R,Moreno-Izco L,Peralta V,Ventura J,Cuesta MJ

更新日期：2016-10-01 00:00:00

abstract：:The effect of comorbidity on rates of suicidal ideation and suicide attempts from an adult general population of former West Germany is investigated. The assessment instrument is a modified German version of the Diagnostic Interview Schedule (DIS), a fully standardized interview for the assessment of selected DSM-III ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Bronisch T,Wittchen HU

更新日期：1994-01-01 00:00:00

abstract：:The ability of humans to predict and explain other people's behaviour by attributing independent mental states such as desires and beliefs to them, is considered to be due to our ability to construct a "Theory of Mind". Recently, several neuroimaging studies have implicated the medial frontal lobes as playing a critic...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Mazza M,Costagliola C,Di Michele V,Magliani V,Pollice R,Ricci A,Di Giovanbattista E,Roncone R,Casacchia M,Galzio RJ

更新日期：2007-02-01 00:00:00

abstract：PURPOSE:Mental health is one of the priorities of the European Commission. Studies of the use and cost of mental health facilities are needed in order to improve the planning and efficiey of mental health resources. We analyze the patterns of mental health service use in multiple clinical settings to identify factors a...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Baca-Garcia E,Perez-Rodriguez MM,Basurte-Villamor I,Quintero-Gutierrez FJ,Sevilla-Vicente J,Martinez-Vigo M,Artes-Rodriguez A,Fernandez del Moral AL,Jimenez-Arriero MA,Gonzalez de Rivera JL

更新日期：2008-03-01 00:00:00

abstract：:Intravascular lymphomatosis (IVL), a rare type of non-Hodgkin's lymphoma, is an uncommon cause of progressive dementia, usually followed by death within a few months of onset of clinical disease. Often this aggressive tumor is only diagnosed at autopsy, because of misleading clinical features mimicking a broad spectru...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Albrecht R,Krebs B,Reusche E,Nagel M,Lencer R,Kretzschmar HA

更新日期：2005-08-01 00:00:00

abstract：:The aim of this study was to reexamine and compare the characteristics of the deficit and nondeficit schizophrenic patients. This cross-sectional study consisted of 62 in- and out-patients, 18-65 years of age, diagnosed with schizophrenia according to DSM-IV. The sociodemographic variables, premorbid adjustment, clini...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Tiryaki A,Yazici MK,Anil AE,Kabakçi E,Karaağaoğlu E,Göğüş A

更新日期：2003-10-01 00:00:00

abstract：:Preventive endeavours in psychotic disorders have been hampered by many obstacles over the past century. One important barrier has been the corrosive pessimism which has attached to the treatment prospects for schizophrenia in particular since the time of Kraepelin, and the isolation of this disorder from progressive ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： McGorry PD

更新日期：1998-01-01 00:00:00

abstract：:The excitatory amino acid glutamate plays an important role in the mammalian CNS. Studies conducted from 1940 to 1950 suggested that oral administration of glutamate could have a beneficial effect on normal and retardate intelligence. The neurotoxic nature of glutamate resulting in excitotoxic lesions (neuronal death)...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Sahai S

更新日期：1990-01-01 00:00:00

abstract：:Severe psychiatric disorders such as schizophrenia are related to cognitive and negative symptoms, which often are resistant to current treatment approaches. The glutamatergic system has been implicated in the pathophysiology of schizophrenia and affective disorders. A key component is the dysfunction of the glutamate...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Hashimoto K,Malchow B,Falkai P,Schmitt A

更新日期：2013-08-01 00:00:00

abstract：:Protein expression of VGF (nonacronymic) is induced by nerve/brain-derived growth factor, neurotrophin 3, and insulin. VGF is synthesized by neurons in the paraventricular (PVN) and supraoptic (SON) nuclei of the hypothalamus. After enzymatic processing, smaller VGF-derived peptides are secreted into the cerebrospinal...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Busse S,Bernstein HG,Busse M,Bielau H,Brisch R,Mawrin C,Müller S,Sarnyai Z,Gos T,Bogerts B,Steiner J

更新日期：2012-08-01 00:00:00

abstract：:Various factors contribute to the development and maintenance of delusions in the context of schizophrenic psychoses. Studies with functional and structural MRI were able to detect neurobiological correlates of paranoid symptoms. Consistent with the neurodevelopmental hypothesis of schizophrenic psychosis, which impli...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Knobel A,Heinz A,Voss M

更新日期：2008-11-01 00:00:00

abstract：:Abnormalities of the cerebellum and default-mode network (DMN) in patients with obsessive-compulsive disorder (OCD) have been widely reported. However, alterations of reciprocal functional connections between the cerebellum and DMN at rest in OCD remain unclear. Forty patients with OCD and 38 gender-, age-, and educat...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Lv D,Ou Y,Chen Y,Yang R,Zhong Z,Jia C,Sun L,Wang Y,Zhang G,Sun Z,Wang W,Wang Y,Wang X,Guo W,Li P

更新日期：2020-12-01 00:00:00

abstract：:Astrocytes are the most numerous cell type within the central nervous system. Early during development they act as guiding structures for migratory neurons; later they are not only the main source for nutrients and growth factors in the brain, but they are also communication partners of neighboring neurons. For this p...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Kirchhoff F,Dringen R,Giaume C

更新日期：2001-08-01 00:00:00

abstract：:The alpha 1C subunit of the L-type voltage-gated calcium channel (CACNA1C) gene is one of the best replicated susceptibility loci for bipolar disorder, schizophrenia and major depression. It is involved in learning, memory and brain plasticity. Genetic studies using functional magnetic resonance imaging (fMRI) reporte...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Krug A,Witt SH,Backes H,Dietsche B,Nieratschker V,Shah NJ,Nöthen MM,Rietschel M,Kircher T

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVE:We tested Kraepelin's dichotomy model by studying the separability of schizophrenia and depression on the basis of symptoms and illness course. MATERIALS AND METHODS:Matched untreated patients with schizophrenia and depression (n = 130 each) and 130 "healthy" controls were assessed from onset to first admiss...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Häfner H,an der Heiden W,Maurer K

更新日期：2008-06-01 00:00:00