Abstract:
:Metabolic syndrome has become a major public health problem worldwide and represents a common clinical condition in countries with a high incidence of obesity and western dietary patterns. Metabolic syndrome associates with common cancers at many sites, including liver, colorectal, and bladder cancers in men, and endometrial, pancreatic, breast post-menopausal, and colorectal cancers in women. However, the role played by each single component of the syndrome on cancer risk is still unclear. For endometrial cancer, obesity and/or high circumference waist explain all the risk associated with the full metabolic syndrome, while for post-menopausal breast cancer, the risk conveyed by metabolic syndrome appears to be greater than its parts, as no single component explains the full risk associated with the syndrome. Future research should cover other avenues in order to elucidate the complexity of biological processes linking metabolic syndrome and cancer.
journal_name
Endocrinejournal_title
Endocrineauthors
Esposito K,Capuano A,Giugliano Ddoi
10.1007/s12020-013-0056-2subject
Has Abstractpub_date
2014-04-01 00:00:00pages
362-4issue
3eissn
1355-008Xissn
1559-0100journal_volume
45pub_type
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