Dehydroepiandrosterone enhances influenza immunization in aged mice.

abstract：:The amygdala and orbitofrontal cortex (OFC) are often thought of as components of a neural circuit that assigns affective significance--or value--to sensory stimuli so as to anticipate future events and adjust behavioral and physiological responses. Much recent work has been aimed at understanding the distinct contrib...

journal_title：Annals of the New York Academy of Sciences

authors： Salzman CD,Paton JJ,Belova MA,Morrison SE

更新日期：2007-12-01 00:00:00

abstract：:Recent years have witnessed an explosive growth in available biological data. This includes a tremendous quantity of sequence data (e.g., biological structures, genetic and physical maps, pathways) generated by genome and transcriptome projects focused on humans, mice, and a multitude of other species. Diabetes resear...

journal_title：Annals of the New York Academy of Sciences

authors： Petrovsky N,Silva D

更新日期：2004-12-01 00:00:00

abstract：:Altered calcium homeostasis may play a key role in the pathophysiology of human heart failure. Levels of sarcoplasmic reticulum (SR) proteins and sarcolemmal Na(+)-Ca2+ exchanger were analyzed by Western blot in failing and nonfailing human myocardium and related to myocardial function. Levels of the SR calcium releas...

journal_title：Annals of the New York Academy of Sciences

authors： Lehnart SE,Schillinger W,Pieske B,Prestle J,Just H,Hasenfuss G

更新日期：1998-09-16 00:00:00

abstract：:It has been proposed that spacetime should be regarded as an evolving block universe, bounded to the future by the present time, which continually extends to the future. This future boundary is defined at each time by measuring proper time along Ricci eigenlines from the start of the universe. A key point, then, is th...

journal_title：Annals of the New York Academy of Sciences

authors： Ellis GF

更新日期：2014-10-01 00:00:00

abstract：:Many features of these gastric vesicles satisfy the requirements for the gastric H+ pump. For example, we have: (a) K+ requirement, (b) KA for K+ of about 30 mM; (c) identical cation sequence for tissue and vesicles, (d) similar anion sequence, (e) localization at the microvillus of the secretory canaliculus, (f) TI+ ...

journal_title：Annals of the New York Academy of Sciences

authors： Sachs G,Berglindh T,Rabon E,Stewart HB,Barcellona ML,Wallmark B,Saccomani G

更新日期：1980-01-01 00:00:00

abstract：:Indirect evidence suggests that dopamine within the brain may participate in the regulation of immune responses in both man and rodents. The aim of the present study was to investigate the possible role played by the specific dopamine D1 receptor subtype within the central amygdala in the modulation of immunity. Mitog...

journal_title：Annals of the New York Academy of Sciences

authors： Nistico G,Caroleo MC,Arbitrio M,Pulvirenti L

更新日期：1994-11-25 00:00:00

abstract：:Glycosylation of alpha-fetoprotein (AFP) by human primary hepatocellular carcinoma (PHC) is abnormal. Concanavalin A (Con A)-affinity molecular variant patterns of serum AFP from patients with PHC are different from those of cord-serum AFP. Different patients with PHC exhibit different Con-A-affinity AFP molecular var...

journal_title：Annals of the New York Academy of Sciences

authors： Smith CJ,Ajdukiewicz A,Kelleher PC

更新日期：1983-01-01 00:00:00

abstract：:Cholinesterase inhibitors used to treat Alzheimer's disease according to the principle of cholinergic replacement therapy have proved to be less beneficial than expected. The present study was designed to investigate the cerebrovascular response to physostigmine and tacrine in the experimental model of lesioning of th...

journal_title：Annals of the New York Academy of Sciences

authors： Peruzzi P,von Euw D,Lacombe P

更新日期：2000-04-01 00:00:00

abstract：:Galanin is widely distributed in enteric nerves and nerve terminals throughout the gastrointestinal (GI) tract. Within the GI tract galanin is best known for its ability to alter smooth muscle contractility and regulate intestinal motility. However, recent studies also indicate that galanin can modulate epithelial ion...

journal_title：Annals of the New York Academy of Sciences

authors： Benya RV,Matkowskyj KA,Danilkovich A,Hecht G

更新日期：1998-12-21 00:00:00

abstract：:Hyperprolactinemia is often observed in lymphocytic hypophysitis (LYH). To clarify the possible autoimmune pituitary involvement in patients with apparently idiopathic hyperprolactinemia we investigated the presence of antipituitary antibodies (APA) in hyperprolactinemic patients with idiopathic hyperprolactinemia and...

journal_title：Annals of the New York Academy of Sciences

authors： De Bellis A,Colao A,Pivonello R,Savoia A,Battaglia M,Ruocco G,Tirelli G,Lombardi G,Bellastella A,Bizzarro A

更新日期：2007-06-01 00:00:00

abstract：:Rehabilitation aims to lessen the physical and cognitive impairments and disabilities of patients with stroke, multiple sclerosis, spinal cord or brain injury, and other neurologic diseases. Conventional approaches beyond compensatory adjustments to disability may be augmented by applying some of the myriad experiment...

journal_title：Annals of the New York Academy of Sciences

authors： Dobkin BH

更新日期：2004-12-01 00:00:00

abstract：:Previous studies, which included predominantly Caucasian populations, examined psychiatric and physical illness and associated suicide risk. We used a nationwide database to reassess the findings in an Asian population, and also analyzed the influence of different onset timing of psychiatric and physical illness and t...

journal_title：Annals of the New York Academy of Sciences

authors： Chang CF,Yeh MK,Chien WC,Chung CH,Li TT,Lai EC

更新日期：2020-02-01 00:00:00

abstract：:In this paper we first present methods and preliminary results of pilot surveys of "serious" mental retardation (IQ less than or equal to 55); the surveys included screening and diagnostic components and were carried out in the less-developed world. Next we discuss two problems raised by these surveys: one is the diag...

journal_title：Annals of the New York Academy of Sciences

authors： Stein Z,Durkin M,Belmont L

更新日期：1986-01-01 00:00:00

abstract：:Neuropsychiatric disorders (i.e., mood disorders and schizophrenia) and inflammation are closely intertwined, and possibly powering each other in a bidirectional loop. Depression facilitates inflammatory reactions and inflammation promotes depression and other neuropsychiatric disorders. Patients with neuropsychiatric...

journal_title：Annals of the New York Academy of Sciences

authors： Bauer ME,Teixeira AL

更新日期：2019-02-01 00:00:00

abstract：:Visual motion is sensed by low-level (energy-based) and high-level (feature-based) mechanisms. Our interest is in the motion detectors underlying the initial ocular following responses (OFR) that are elicited at ultrashort latencies by sudden motions of large images. OFR were elicited in humans by applying horizontal ...

journal_title：Annals of the New York Academy of Sciences

authors： Chen KJ,Sheliga BM,Fitzgibbon EJ,Miles FA

更新日期：2005-04-01 00:00:00

abstract：:Statistical learning is a set of cognitive mechanisms allowing for extracting regularities from the environment and segmenting continuous sensory input into discrete units. The current study used functional magnetic resonance imaging (fMRI) (N = 25) in conjunction with an artificial language learning paradigm to provi...

journal_title：Annals of the New York Academy of Sciences

authors： Ordin M,Polyanskaya L,Soto D

更新日期：2020-05-01 00:00:00

abstract：:Asbestos contamination of relatively contained environments within structures can occur under many conditions and in association with various activities. Such contamination persists and can potentially expose all structure users. The more significant contamination levels are associated with disturbance of friable asbe...

journal_title：Annals of the New York Academy of Sciences

authors： Sawyer RN

更新日期：1979-01-01 00:00:00

abstract：:Our objective was to learn the prevalence of spotted fever group (SFG) Rickettsia detected in ticks in La Rioja, in the north of Spain. From 2001 to 2005, 496 ticks representing 7 tick species were analysed at the Hospital de La Rioja. Ticks were removed from humans with or without rickettsial syndrome (n = 59) or col...

journal_title：Annals of the New York Academy of Sciences

authors： Oteo JA,Portillo A,Santibáñez S,Pérez-Martínez L,Blanco JR,Jiménez S,Ibarra V,Pérez-Palacios A,Sanz M

更新日期：2006-10-01 00:00:00

abstract：:The human endometrium is an extremely sensitive target for steroid hormones. During the menstrual cycle, this tissue undergoes dynamic changes that are reflected on the surface morphology of the epithelium and that can be followed by scanning electron microscopy. The morphologic changes peak at the midsecretory phase,...

journal_title：Annals of the New York Academy of Sciences

authors： Nikas G,Makrigiannakis A,Hovatta O,Jones HW Jr

更新日期：2000-01-01 00:00:00

abstract：:The electron microscopical studies presented here show that characteristic morphological alterations in mitochondria are a very early hallmark of the hepatocellular apoptotic program. Before chromatin condensation occurs, the outer mitochondrial membrane is focally disrupted and the inner membrane protrudes through th...

journal_title：Annals of the New York Academy of Sciences

authors： Angermüller S,Schümann J,Fahimi HD,Tiegs G

更新日期：1999-01-01 00:00:00

abstract：:Sm-p80-based vaccine efficacy for Schistosoma mansoni was evaluated in a baboon model of infection and disease. The study was designed to replicate a human vaccine implementation scenario for endemic regions in which vaccine would be administered following drug treatment of infected individuals. In our study, the Sm-p...

journal_title：Annals of the New York Academy of Sciences

authors： Siddiqui AJ,Molehin AJ,Zhang W,Ganapathy PK,Kim E,Rojo JU,Redman WK,Sennoune SR,Sudduth J,Freeborn J,Hunter D,Kottapalli KR,Kottapalli P,Wettashinghe R,van Dam GJ,Corstjens PLAM,Papin JF,Carey D,Torben W,Ahmad G,S

更新日期：2018-08-01 00:00:00

abstract：:A recent study based on the SPoARC effect (spatial position association response codes) showed that culture heavily shapes cognition and more specifically the way thought is organized; when Western adults are asked to keep in mind a sequence of colors, they mentally organize them from left to right, whereas right-to-l...

journal_title：Annals of the New York Academy of Sciences

authors： Guida A,Mosinski F,Cipora K,Mathy F,Noël Y

更新日期：2020-10-01 00:00:00

abstract：:Phosphorus nuclear magnetic resonance studies of various normal and dystrophic muscles have demonstrated differences in phosphodiester contents. Dystrophic chicken pectoralis muscle contains elevated levels of the diester SEP, and Duchenne dystrophic human leg muscle lacks the diester GPC. It is shown that SEP may be ...

journal_title：Annals of the New York Academy of Sciences

authors： Chalovich JM,Burt CT,Danon MJ,Glonek T,Bárány M

更新日期：1979-01-01 00:00:00

abstract：:A radioimmunoassay method (RIA) with specific antisera for human and rat alpha fetoprotein (AFP) was used to study the evolution of AFP levels in humans and rats, respectively, throughout the life span. Sera of 66 rats, aged 3-70 weeks, as well as sera of 201 clinically well children, 192 healthy blood donors, and 16...

journal_title：Annals of the New York Academy of Sciences

authors： Masseyeff R,Gilli J,Krebs B,Calluaud A,Bonet C

更新日期：1975-08-22 00:00:00

abstract：:Primary hyperparathyroidism (PHPT) results from excessive secretion of parathyroid hormone (PTH), and catabolic and anabolic effects of PTH on bone may lead to overall deleterious effects on skeleton. The aim of this study was to analyze the changes in lumbar spine bone mineral density (BMD) in patients with PHPT who ...

journal_title：Annals of the New York Academy of Sciences

authors： Lumachi F,Camozzi V,Ermani M,Nardi A,Luisetto G

更新日期：2007-11-01 00:00:00

abstract：:Nanomedicine is the application of nanotechnology to the discipline of medicine: the use of nanoscale materials for the diagnosis, monitoring, control, prevention, and treatment of disease. Nanomedicine holds tremendous promise to revolutionize medicine across disciplines and specialties, but this promise has yet to b...

journal_title：Annals of the New York Academy of Sciences

authors： Tinkle S,McNeil SE,Mühlebach S,Bawa R,Borchard G,Barenholz YC,Tamarkin L,Desai N

更新日期：2014-04-01 00:00:00

abstract：:B-1 cells represent a subpopulation of B cells that has been extensively studied in mice and shown to spontaneously generate natural antibody that provides antimicrobial protection and helps dispose of cellular debris. Mouse B-1 cells originate from distinct progenitors and express additional immune properties that in...

journal_title：Annals of the New York Academy of Sciences

authors： Rothstein TL,Quach TD

更新日期：2015-12-01 00:00:00

abstract：:Monoclonal antibodies reactive with desmin (D3 and D76) have been generated and their specificities validated by immunoblots, RIAs, and immunocytochemistry. No cross-reaction with other IFPs has been observed. The McAbs recognized different epitopes but both reside in the amino-terminal rod domain of desmin. Whereas M...

journal_title：Annals of the New York Academy of Sciences

authors： Fischman DA,Danto SI

更新日期：1985-01-01 00:00:00

abstract：:"Vascular anomalies" represents a spectrum of vascular lesions, of unclear etiology and often with unpredictable behavior. Patients with vascular anomalies represent a unique population, in that they have focal aberrations of vascular development (in vascular malformations) or vascular proliferation (in hemangiomas). ...

journal_title：Annals of the New York Academy of Sciences

authors： Blei F

更新日期：2008-01-01 00:00:00

abstract：:Deposition of amyloid beta protein in the brain is the major pathological feature of Alzheimer's disease. Amyloid beta protein is generated from beta-amyloid precursor protein by beta-secretase and gamma-secretase. Proteolytic processing of amyloid precursor protein at the beta site by BACE1 is essential to generate a...

journal_title：Annals of the New York Academy of Sciences

authors： Zhou W,Qing H,Tong Y,Song W

更新日期：2004-12-01 00:00:00