Abstract:
:The interface between thyroid hormone action and neuropsychiatric function is intricate, and several mechanisms of thyroid hormone uptake into brain tissues, hormone activation, and influences on neurotransmitter generation have been identified. Symptoms of hypothyroidism are nonspecific, whereas those attributed to thyrotoxicosis may be more characteristic. Neuropsychiatric manifestations triggered by thyroid dysfunction likely respond well to reestablishment of the euthyroid state, although some patients have persistent complaints. The addition of LT3 to ongoing LT4 replacement has yet to be definitively shown to be advantageous. Treatment of euthyroid depression with LT3 in addition to antidepressant therapy lacks convincing evidence of superior outcomes.
journal_name
Endocrinol Metab Clin North Amjournal_title
Endocrinology and metabolism clinics of North Americaauthors
Feldman AZ,Shrestha RT,Hennessey JVdoi
10.1016/j.ecl.2013.05.005subject
Has Abstractpub_date
2013-09-01 00:00:00pages
453-76issue
3eissn
0889-8529issn
1558-4410pii
S0889-8529(13)00040-6journal_volume
42pub_type
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journal_title:Endocrinology and metabolism clinics of North America
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journal_title:Endocrinology and metabolism clinics of North America
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journal_title:Endocrinology and metabolism clinics of North America
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journal_title:Endocrinology and metabolism clinics of North America
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journal_title:Endocrinology and metabolism clinics of North America
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journal_title:Endocrinology and metabolism clinics of North America
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journal_title:Endocrinology and metabolism clinics of North America
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journal_title:Endocrinology and metabolism clinics of North America
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journal_title:Endocrinology and metabolism clinics of North America
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journal_title:Endocrinology and metabolism clinics of North America
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journal_title:Endocrinology and metabolism clinics of North America
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journal_title:Endocrinology and metabolism clinics of North America
pub_type: 杂志文章,评审
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journal_title:Endocrinology and metabolism clinics of North America
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journal_title:Endocrinology and metabolism clinics of North America
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journal_title:Endocrinology and metabolism clinics of North America
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journal_title:Endocrinology and metabolism clinics of North America
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journal_title:Endocrinology and metabolism clinics of North America
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journal_title:Endocrinology and metabolism clinics of North America
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journal_title:Endocrinology and metabolism clinics of North America
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journal_title:Endocrinology and metabolism clinics of North America
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journal_title:Endocrinology and metabolism clinics of North America
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journal_title:Endocrinology and metabolism clinics of North America
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journal_title:Endocrinology and metabolism clinics of North America
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journal_title:Endocrinology and metabolism clinics of North America
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journal_title:Endocrinology and metabolism clinics of North America
pub_type: 杂志文章,评审
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journal_title:Endocrinology and metabolism clinics of North America
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