Effect of exchange transfusion on bilirubin binding.

Abstract:

:The bilirubin titration point--the lowest bilirubin concentration at which loosely bound bilirubin could be demonstrated by Sephadex gel filtration--was determined in samples collected before, during, and on completion of 17 exchange transfusions as well as in the discarded and donor blood. The bilirubin titration point expressed either as bilirubin concentration or as bilirubin/albumin molar ratio failed to be increased by the exchange transfusion and, in each case at the end of the procedure, the titration point was below the expected level, assuming that the donor albumin was going to retain its binding properties in the infant's circulation. The bilirubin titration point was also depressed in the discarded blood, and the depression was inversely related to the amount of bilirubin removed by the exchange transfusion (expressed as mg/kg of body weight/mg of initial bilirubin concentration). These results are interpreted as an indication that interfering substances are responsible for the decreased binding of bilirubin in newborn, particularly preterm, infants. In practical terms the criteria for a repeat exchange transfusion should be the same as for the initial one, as no change in the bilirubin binding properties of the serum is likely to occur following exchange transfusion.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Valaes T,Hyte M

subject

Has Abstract

pub_date

1977-06-01 00:00:00

pages

881-7

issue

6

eissn

0031-4005

issn

1098-4275

journal_volume

59

pub_type

杂志文章
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    authors: Carstensen H,Nilsson KO,Nettelblad SC,Cederlund CG,Hildell J

    更新日期:1986-06-01 00:00:00

  • Self-referral and serious illness in children with fever.

    abstract:OBJECTIVE:The goal of this study was to evaluate parents' capability to assess their febrile child's severity of illness and decision to present to the emergency department. We compared children referred by a general practitioner (GP) with those self-referred on the basis of illness-severity markers. METHODS:This was ...

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    pub_type: 杂志文章

    doi:10.1542/peds.2011-1952

    authors: van Ierland Y,Seiger N,van Veen M,van Meurs AH,Ruige M,Oostenbrink R,Moll HA

    更新日期:2012-03-01 00:00:00

  • Respiratory syncytial virus immune globulin treatment of RSV lower respiratory tract infection in previously healthy children.

    abstract:OBJECTIVE:To evaluate the efficacy of high titer respiratory syncytial virus (RSV) immune globulin (RSVIG) in the treatment of previously healthy children hospitalized with proven RSV lower tract infection (LRI). METHOD:Infants and young children

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    authors: Rodriguez WJ,Gruber WC,Groothuis JR,Simoes EA,Rosas AJ,Lepow M,Kramer A,Hemming V

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    abstract::There is general agreement that case management should be provided to children with chronic illnesses, yet it is not clear who should provide this service. A survey of physicians and parents of children with chronic illnesses was conducted to evaluate the practice and views of pediatricians and compare their assessmen...

    journal_title:Pediatrics

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    doi:

    authors: Liptak GS,Revell GM

    更新日期:1989-09-01 00:00:00

  • Endemic iron deficiency associated with Helicobacter pylori infection among school-aged children in Alaska.

    abstract:OBJECTIVES:Rural Alaska Natives have a high prevalence of iron deficiency and Helicobacter pylori infection. The objective of this study was to estimate the prevalence of iron deficiency, iron-deficiency anemia, and active H pylori infection among school-aged children in rural Alaska. METHODS:We enrolled 68% (688) of ...

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    doi:10.1542/peds.2005-1129

    authors: Baggett HC,Parkinson AJ,Muth PT,Gold BD,Gessner BD

    更新日期:2006-03-01 00:00:00

  • Food protein-induced enterocolitis syndrome caused by solid food proteins.

    abstract:BACKGROUND:Infantile food protein-induced enterocolitis syndrome (FPIES) is a severe, cell-mediated gastrointestinal food hypersensitivity typically provoked by cow's milk or soy. Solid foods are rarely considered a cause. OBJECTIVE:To describe the clinical characteristics and natural history of FPIES provoked by soli...

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    doi:10.1542/peds.111.4.829

    authors: Nowak-Wegrzyn A,Sampson HA,Wood RA,Sicherer SH

    更新日期:2003-04-01 00:00:00

  • Issues in estimating the prevalence of fetal alcohol syndrome: examination of 2 counties in New York State.

    abstract:OBJECTIVE:Two demographically similar counties included in the New York Fetal Alcohol Syndrome Surveillance Network had very different prevalence rates. This study examined the components of the surveillance in an attempt to discover the reasons for this discrepancy. METHODS:Erie County and Monroe County were the 2 mo...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2006-0610

    authors: Druschel CM,Fox DJ

    更新日期:2007-02-01 00:00:00

  • A system for individualized dosing of intravenous aminophylline using a programmable calculator.

    abstract::A program that calculates a value of clearance for an individual patient prior to reaching steady state in the early stages of aminophylline therapy is presented. The program is written for the Texas Instruments TI-59 programmable calculator and may be used with or without the PC-100C printer. The program can provide ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Mitsuoka JC,Fleck RJ

    更新日期:1984-01-01 00:00:00

  • Predicting deterioration in previously healthy infants hospitalized with respiratory syncytial virus infection.

    abstract:OBJECTIVE:To estimate the incidence of clinical deterioration leading to intensive care unit transfer in previously healthy infants with respiratory syncytial virus (RSV) infection hospitalized on a general pediatric unit and, to assess the hypothesis that history, physical examination, oximetry, and chest radiographic...

    journal_title:Pediatrics

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    doi:10.1542/peds.104.3.463

    authors: Brooks AM,McBride JT,McConnochie KM,Aviram M,Long C,Hall CB

    更新日期:1999-09-01 00:00:00

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    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2006-2065

    authors: Abdel-Rahman SM,Simon S,Wright KJ,Ndjountche L,Gaedigk A

    更新日期:2006-12-01 00:00:00

  • Children in alcohol-related motor vehicle crashes.

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    journal_title:Pediatrics

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    更新日期:1986-06-01 00:00:00

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    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2012-0839

    authors: Heinonen K,Pesonen AK,Lahti J,Pyhälä R,Strang-Karlsson S,Hovi P,Järvenpää AL,Eriksson JG,Andersson S,Kajantie E,Raikkonen K

    更新日期:2013-01-01 00:00:00

  • Nebulized hypertonic saline without adjunctive bronchodilators for children with bronchiolitis.

    abstract:OBJECTIVE:The goal was to determine an adverse event rate for nebulized hypertonic saline solution administered without adjunctive bronchodilators for infants with bronchiolitis. METHODS:This was a retrospective cohort study of the use of nebulized 3% saline for children<2 years of age who were hospitalized with the p...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2009-3105

    authors: Ralston S,Hill V,Martinez M

    更新日期:2010-09-01 00:00:00

  • Screen Violence and Youth Behavior.

    abstract::Violence in screen entertainment media (ie, television, film, video games, and the Internet), defined as depictions of characters (or players) trying to physically harm other characters (or players), is ubiquitous. The Workgroup on Media Violence and Violent Video Games reviewed numerous meta-analyses and other releva...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.2016-1758T

    authors: Anderson CA,Bushman BJ,Bartholow BD,Cantor J,Christakis D,Coyne SM,Donnerstein E,Brockmyer JF,Gentile DA,Green CS,Huesmann R,Hummer T,Krahé B,Strasburger VC,Warburton W,Wilson BJ,Ybarra M

    更新日期:2017-11-01 00:00:00

  • Fathers' experiences in the neonatal intensive care unit: a search for control.

    abstract:OBJECTIVE:This qualitative study aimed at understanding the experiences of fathers of very ill neonates in the NICU. METHODS:Sixteen fathers of very ill and/or very preterm infants who had been in the NICU for >30 days were interviewed by a male physician. Fathers were asked about their level of comfort with or concer...

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    pub_type: 杂志文章

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    authors: Arockiasamy V,Holsti L,Albersheim S

    更新日期:2008-02-01 00:00:00

  • Neurofibromatosis type 1 revisited.

    abstract::Neurofibromatosis type 1 (NF1) is an autosomal dominant condition with a worldwide incidence of approximately 1 per 2500 to 3000 individuals. Caused by a germ-line-inactivating mutation in the NF1 gene on chromosome 17, the disease is associated with increased morbidity and mortality. In the past several years, signif...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.2007-3204

    authors: Williams VC,Lucas J,Babcock MA,Gutmann DH,Korf B,Maria BL

    更新日期:2009-01-01 00:00:00

  • Global Climate Change and Children's Health.

    abstract::Rising global temperatures are causing major physical, chemical, and ecological changes in the planet. There is wide consensus among scientific organizations and climatologists that these broad effects, known as "climate change," are the result of contemporary human activity. Climate change poses threats to human heal...

    journal_title:Pediatrics

    pub_type: 指南,杂志文章

    doi:10.1542/peds.2015-3232

    authors: COUNCIL ON ENVIRONMENTAL HEALTH.

    更新日期:2015-11-01 00:00:00

  • Ostensible versus actual reasons for seeking pediatric attention: another look at the parental ticket of admission.

    abstract::The presentation of parental anxiety that appears excessive in view of the nature of the child's "chief complaint" is a frequent occurrence in pediatric practice. This study reviews 370 sick-patient visits in one pediatric office during a three-month period. Additional questioning in the area of parental anxieties con...

    journal_title:Pediatrics

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  • Children Exposed to Maltreatment: Assessment and the Role of Psychotropic Medication.

    abstract::Pediatricians regularly care for children who have experienced child maltreatment. Child maltreatment is a risk factor for a broad range of mental health problems. Issues specific to child maltreatment make addressing emotional and behavioral challenges among maltreated children difficult. This clinical report focuses...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2019-3751

    authors: Keeshin B,Forkey HC,Fouras G,MacMillan HL,AMERICAN ACADEMY OF PEDIATRICS, COUNCIL ON CHILD ABUSE AND NEGLECT, COUNCIL ON FOSTER CARE, ADOPTION, AND KINSHIP CARE, AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, COMMITTEE ON CHILD MALTREATMEN

    更新日期:2020-02-01 00:00:00

  • American Academy of Pediatrics: Medical conditions affecting sports participation.

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    journal_title:Pediatrics

    pub_type: 指南,杂志文章

    doi:10.1542/peds.107.5.1205

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    更新日期:2001-05-01 00:00:00

  • Neurodevelopmental outcomes of extremely low birth weight infants exposed prenatally to dexamethasone versus betamethasone.

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    pub_type: 杂志文章

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    authors: Lee BH,Stoll BJ,McDonald SA,Higgins RD,National Institute of Child Health and Human Development Neonatal Research Network.

    更新日期:2008-02-01 00:00:00

  • Perinatal Risk Factors for Feeding and Eating Disorders in Children Aged 0 to 3 Years.

    abstract:OBJECTIVE:To describe the incidence, age at diagnosis, and associations between perinatal risk factors of feeding and eating disorders (FED) diagnosed at hospital in children aged 0 to 3 years. METHODS:A nationwide cohort of 901 227 children was followed until 48 months of age in the national registers from 1997 to 20...

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    pub_type: 杂志文章

    doi:10.1542/peds.2015-2575

    authors: Hvelplund C,Hansen BM,Koch SV,Andersson M,Skovgaard AM

    更新日期:2016-02-01 00:00:00

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    pub_type: 杂志文章

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    更新日期:1989-03-01 00:00:00

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    pub_type: 杂志文章

    doi:

    authors: Horwood SP,Boyle MH,Torrance GW,Sinclair JC

    更新日期:1982-05-01 00:00:00

  • A double-blind, placebo-controlled, randomized trial of montelukast for acute bronchiolitis.

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  • Mechanical vibration in neonatal transport.

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