Abstract:
OBJECTIVES:This article reviews evidence regarding effects of psychotherapy on overall cancer survival time. Special emphasis is given to research on adverse effects of depression on cancer survival, breast cancer, and mediating psychophysiological pathways linking psychosocial support to longer survival. DESIGN:It reviews all published clinical trials addressing effects of psychotherapy on cancer survival, emphasizing depression, breast cancer, and psychophysiological evidence linking stress, depression, and support to cancer survival. METHODS:Systematic literature review and synthesis. RESULTS:Eight of 15 published trials indicate that psychotherapy enhances cancer survival time. No studies show an adverse effect of psychotherapy on cancer survival. Potential psychophysiological mechanisms linking stress to shorter survival include dysregulation of diurnal cortisol, increased pro-inflammatory cytokines, reduced natural killer cell activity, shorter telomeres and lower telomerase activity, glucocorticoid-mediated suppression of p53 and BrCA1 gene expression, and sympathetic nervous system activation of vascular endothelial growth factor. CONCLUSIONS:Stress and support affect the course of cancer progression. STATEMENT OF CONTRIBUTION:What is known? Stress and support have been thought to be related to cancer risk and progression, but evidence has been mixed. Depression is a natural co-morbid condition with cancer. It has not been clear how stress and support could physiologically affect the rate of cancer progression. Immune function was not thought to have much relevance to cancer progression. Few other physiological mechanisms linking stress to cancer progression were known. What does this paper add? There is evidence from 15 RCTs indicating that effective psychosocial support improves quantity as well as quality of life with cancer. There is evidence that chronic depression predicts poorer prognosis with cancer. Dysregulated circadian cortisol patterns predict more rapid cancer progression. Inflammatory processes affect cancer growth and progression. Sympathetic nervous system activity, telomere length, telomerase activity, and oncogene expression are affected by stress and can affect cancer growth.
journal_name
Br J Health Psycholjournal_title
British journal of health psychologyauthors
Spiegel Ddoi
10.1111/bjhp.12061subject
Has Abstractpub_date
2014-09-01 00:00:00pages
465-85issue
3eissn
1359-107Xissn
2044-8287journal_volume
19pub_type
杂志文章,评审abstract:OBJECTIVES:This study examines the hypothesis that a past history of heart interventions will moderate the relationship between psychosocial factors (stressful life events, social support, perceived stress, having a current partner, having a past diagnosis of depression or anxiety over the past 3 years, time pressure, ...
journal_title:British journal of health psychology
pub_type: 杂志文章
doi:10.1111/bjhp.12011
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVES:For the effective treatment of childhood obesity, intervention attendance and behaviour change at home are both important. The purpose of this study was to qualitatively explore influences on attendance and behaviour change during a family-based intervention to treat childhood obesity in the North West of En...
journal_title:British journal of health psychology
pub_type: 杂志文章
doi:10.1111/bjhp.12456
更新日期:2021-02-01 00:00:00
abstract:OBJECTIVE:The aims of this study were twofold: to determine in what way people with a non-fatal chronic illness experience positive change after the onset of their illness, and to determine whether comparing with other people with Ménière's disease influenced perceiving this change. DESIGN:Using a longitudinal method,...
journal_title:British journal of health psychology
pub_type: 杂志文章
doi:10.1348/135910708X383598
更新日期:2009-11-01 00:00:00
abstract:BACKGROUND:Studying and understanding pathways to diagnosis and treatment is vital for the development of successful interventions to encourage early detection, presentation, and diagnosis. An existing framework posited to describe the decisional and behavioural processes that occur prior to treatment (Andersen et al.'...
journal_title:British journal of health psychology
pub_type: 杂志文章,评审
doi:10.1111/j.2044-8287.2012.02077.x
更新日期:2013-02-01 00:00:00
abstract:OBJECTIVES:Psychosocial factors have previously been linked with survival and mortality in cancer populations. Little evidence is available about the relationship between these factors and outcomes in gynaecologic cancer populations, particularly endometrial cancer, the fourth most common cancer among women. This study...
journal_title:British journal of health psychology
pub_type: 杂志文章
doi:10.1111/bjhp.12070
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:A school-based vaccination programme to prevent infection with the human papillomavirus (HPV), the virus that causes cervical cancer, began in October 2008 in England. The present study evaluated the role of temporal perspective in the formation of attitudes and intentions towards the vaccine. DESIGN:A cross...
journal_title:British journal of health psychology
pub_type: 杂志文章
doi:10.1348/135910709X437092
更新日期:2010-02-01 00:00:00
abstract:OBJECTIVES:Evidence is accumulating that positive mental states are more than the absence of symptoms, and may play an independent role in health outcomes. The aim of this study is to compare the characteristics and determinants of positive and negative mental states in a population sample. DESIGN:A novel analysis of ...
journal_title:British journal of health psychology
pub_type: 杂志文章
doi:10.1348/135910703762879246
更新日期:2003-02-01 00:00:00
abstract:OBJECTIVE:Based on the idea of the 'IKEA effect', assuming that individuals like self-created objects more than objects created by someone else, this study hypothesizes that parents' involvement of their children in meal planning and preparation is positively related to vegetable intake, mediated via liking vegetables....
journal_title:British journal of health psychology
pub_type: 杂志文章
doi:10.1111/bjhp.12385
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVES:This study reports an application of the health belief model (HBM) to the prediction of breast self-examination (BSE) among women with a family history of breast cancer. The study also considered the influence of breast cancer worries and past behaviour. METHODS:Eight hundred and thirty-three women complete...
journal_title:British journal of health psychology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1348/135910704X24752
更新日期:2005-02-01 00:00:00
abstract::AIM: Young age at diagnosis of breast cancer is a negative prognostic factor, but early detection of breast pathology may improve prognosis. The present study examined the role of health perceptions (Health Belief Model; HBM) in young women's breast self-examination (BSE). It was hypothesized that cues to action, heal...
journal_title:British journal of health psychology
pub_type: 杂志文章
doi:10.1348/135910701169269
更新日期:2001-11-01 00:00:00
abstract::We examined the relation of social problem-solving abilities to distress experienced by family members assuming a caregiving role for a loved one who had recently incurred a severe physical disability. Family members completed measures of problem-solving, depression and health, while their loved one participated in an...
journal_title:British journal of health psychology
pub_type: 杂志文章
doi:10.1348/135910703321649132
更新日期:2003-05-01 00:00:00
abstract:OBJECTIVES:Although health messages communicating the role of genetics in health and disease development are increasingly prevalent in our society, no research has examined whether the general public perceives such messages as believable or personally relevant. We examined whether the general public accepted genetic he...
journal_title:British journal of health psychology
pub_type: 临床试验,杂志文章
doi:10.1348/135910710X494574
更新日期:2010-11-01 00:00:00
abstract:OBJECTIVES:Excessive alcohol consumption increases when students enter university. This study tests whether combining (1) messages that target key beliefs from the theory of planned behaviour (TPB) that underlie binge drinking, (2) a self-affirmation manipulation to reduce defensive processing, and (3) implementation i...
journal_title:British journal of health psychology
pub_type: 杂志文章,随机对照试验
doi:10.1111/bjhp.12277
更新日期:2018-02-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to investigate whether a breast cancer diagnosis, personal assertiveness (i.e. frequency of assertive behaviour and tension associated with this behaviour), and partners' relationship-focused coping (i.e. active engagement and protective buffering) were sources of variation in patien...
journal_title:British journal of health psychology
pub_type: 杂志文章
doi:10.1348/135910707X252431
更新日期:2008-11-01 00:00:00
abstract:OBJECTIVE:The aim of the present study was to measure the extent to which illness perceptions and coping strategies are associated with the levels of psychological distress amongst allergy sufferers. DESIGN AND METHOD:One hundred and fifty-six allergy sufferers (all members of Allergy U.K.) completed a postal survey c...
journal_title:British journal of health psychology
pub_type: 杂志文章
doi:10.1348/135910706X173278
更新日期:2008-02-01 00:00:00
abstract:OBJECTIVES:To develop a questionnaire to measure the extent and severity of the concerns of people with an implanted cardioverter defibrillator. DESIGN:Items were generated from patient interviews, expert review and the research literature on patients' worries and concerns. A pilot version was administered to a series...
journal_title:British journal of health psychology
pub_type: 杂志文章
doi:10.1348/135910705X52264
更新日期:2006-05-01 00:00:00
abstract:OBJECTIVES:The movement of patients in magnetic resonance imaging (MRI) scanners results in motion artefacts which impair image quality. Non-completion of scans leads to delay in diagnosis and increased costs. This study aimed to develop and evaluate an intervention to enable patients to stay still in MRI scanners (red...
journal_title:British journal of health psychology
pub_type: 杂志文章,随机对照试验
doi:10.1111/bjhp.12132
更新日期:2015-09-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to investigate the one-year development of self-reported sleep problems in workers with no sleep problem at baseline, and to evaluate the role of work stress in the etiology of a new episode. DESIGN:A prospective design was employed. METHODS:A total of 816 employees with no sleepi...
journal_title:British journal of health psychology
pub_type: 杂志文章,多中心研究
doi:10.1348/135910704773891005
更新日期:2004-05-01 00:00:00
abstract::Particularly in the health domain, humans thrive to reach an equilibrium between maximizing pleasure and minimizing harm. We propose that a cognitive strategy people employ to reach this equilibrium is the activation of Compensatory Health Beliefs (CHBs). CHBs are beliefs that the negative effects of an unhealthy beha...
journal_title:British journal of health psychology
pub_type: 杂志文章
doi:10.1348/135910705X52237
更新日期:2006-02-01 00:00:00
abstract:OBJECTIVES: The present study explored factors that underpin increased internalization (i.e., perceived autonomy) in motivation towards exercise over a 1-year period in adolescent girls. DESIGN: A mixed methods prospective study. METHODS: A total of 107 girls (mean age = 13.28 years) reported their exercise behaviour...
journal_title:British journal of health psychology
pub_type: 杂志文章
doi:10.1111/j.2044-8287.2011.02053.x
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVES:Partners are a significant influence on individuals' health, and concordance in health behaviours increases over time in couples. Several theories suggest that couple-focused interventions for health behaviour change may therefore be more effective than individual interventions. DESIGN:A systematic review o...
journal_title:British journal of health psychology
pub_type: 杂志文章,评审
doi:10.1111/bjhp.12227
更新日期:2017-05-01 00:00:00
abstract::Epidemiologic studies on hypochondriasis are very rare and have not been included in large North American community surveys until now. In order to gain information on the prevalence as well as the socio-demographic characteristics of hypochondriasis, the following community study was carried out. Analyses are based on...
journal_title:British journal of health psychology
pub_type: 杂志文章
doi:10.1348/135910706X146034
更新日期:2007-11-01 00:00:00
abstract:OBJECTIVE:Reviews have called for integrative, theoretically informed models of the 'hundreds of associations' (Miller & Slap, 1989, p. 131) between psychosocial measures and adolescent smoking (e. g. Tyas & Pederson, 1998). Such a model was tested. METHOD:A prospective, classroom-based survey measuring previously ide...
journal_title:British journal of health psychology
pub_type: 杂志文章
doi:10.1348/1359107041557075
更新日期:2004-09-01 00:00:00
abstract:OBJECTIVES:Sickle cell disease (SCD) is the UK's most common blood disorder causing sickle shaped red blood cells to block small blood vessels inducing both acute and chronic pain. A crucial factor in determining quality of life for those with SCD is the severity, timing and number of painful sickling episodes. However...
journal_title:British journal of health psychology
pub_type: 杂志文章
doi:10.1111/bjhp.12157
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:Health behaviour models focus primarily on intrapersonal constructs (e.g., self-efficacy) which are good predictors of intention but less so of actual behaviour. Influences from the social environment, namely from close others, may improve prediction of engagement in ongoing behaviour. OBJECTIVES:This study...
journal_title:British journal of health psychology
pub_type: 杂志文章
doi:10.1111/bjhp.12195
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVES:To explore the impact of the secondary school environment on young people with continence problems. DESIGN:In-depth qualitative semi-structured interviews. METHODS:We interviewed 20 young people aged 11-19 years (11 female and nine male) with continence problems (daytime wetting, bedwetting, and/or soiling...
journal_title:British journal of health psychology
pub_type: 杂志文章,多中心研究
doi:10.1111/bjhp.12284
更新日期:2018-05-01 00:00:00
abstract:OBJECTIVE:Renal transplantation (RTx) is considered the treatment of choice for end-stage renal disease (ESRD) given its association with lower mortality, and improved overall quality of life and psychological functioning compared to dialysis. However, much less is known about which factors underlie these psychological...
journal_title:British journal of health psychology
pub_type: 杂志文章
doi:10.1111/bjhp.12243
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVE:The present study examined the effects of caregiving stress and ageing on neutrophil function in young and older individuals. DESIGN:As a model of caregiving, young parents (aged 38.3 ± 4.78) of children with developmental disabilities were recruited and compared to older caregivers (aged 70 ± 6.03), full ti...
journal_title:British journal of health psychology
pub_type: 杂志文章
doi:10.1111/bjhp.12156
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVES:To explore quality of life outcomes and the factors that influenced adjustment among individuals diagnosed with an acoustic neuroma. DESIGN:This qualitative study involved a focus group design. METHODS:Twenty-one participants who had been diagnosed with and/or treated for an acoustic neuroma since 2000 att...
journal_title:British journal of health psychology
pub_type: 杂志文章
doi:10.1348/135910708X372527
更新日期:2009-09-01 00:00:00
abstract:OBJECTIVES:This study prospectively investigated the relationship between life-events, perceived stress, and quality of life (QOL) following breast cancer diagnosis, using the bio-behavioural model of cancer stress as a framework. DESIGN:A longitudinal, self-report design was used. METHODS:Three waves of data from 10...
journal_title:British journal of health psychology
pub_type: 杂志文章
doi:10.1348/135910709X412459
更新日期:2009-11-01 00:00:00