Abstract：
BACKGROUND:The aim of this study is to reveal demographic and clinical features of Behçet's disease (BD) in a Turkish population. METHODS:We retrospectively evaluated the clinical findings of 521 patients with BD. RESULTS:A total of 521 patients (287 female and 234 male) were included in this study. Onset signs: oral ulceration (72.7%) was followed by genital ulceration (3.1%), ocular involvement (1.0%), and erythema nodosum-like lesions (ENLL) (0.2%). In 120 patients (23%), the onset manifestation compromised more than one symptom. During follow-up, in females and males respectively, oral ulceration was found in 100%, genital ulceration in 90.9% and in 82.5%, papulopustular lesions in 52.6% and in 71.4%, positive pathergy test in 45.3% and in 48.7%, ENLL in 43.6% and in 31.6%, ocular involvement in 36.9% and in 58.1%, gastrointestinal involvement in 6.6% and in 5.6%, joint involvement in 4.2% and in 6.4%, vascular involvement in 1.7% and in 10.6%, neurological involvement in 0% and in 4.7% and pulmonary involvement in 0.7% and in 0.7%. Genital ulceration and ENLL were found to be statistically higher in females than males. Papulopustular lesions and ocular, neurological, and vascular involvement were significantly higher in males than females. CONCLUSIONS:In our study, systemic involvement was higher in males than females, as the disease is more severe in males than females. As the only initial finding of the disease can be genital ulceration or ocular manifestations, gynecologists, urologists, ophthalmologists, and family practitioners must keep in mind BD as a differential diagnosis.
journal_name
Int J Dermatoljournal_title
International journal of dermatologyauthors
Balta I,Akbay G,Kalkan G,Eksioglu Mdoi
10.1111/j.1365-4632.2012.05756.xsubject
Has Abstractpub_date
2014-05-01 00:00:00pages
564-9issue
5eissn
0011-9059issn
1365-4632journal_volume
53pub_type
杂志文章abstract：BACKGROUND:An epidemic of cercarial dermatitis caused by Schistosoma spindale cercaria occurred in November 1988 in a district called Chaiya, Surajthani province, in Southern Thailand. CASE REPORTS:Fifty-eight Thai farmers in Chaiya, Surajthani gave a history of itch following immersion in water while planting rice. T...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4362.1993.tb01448.x
更新日期：1993-02-01 00:00:00
abstract：:Melasma is characterized by a facial hypermelanosis of light to dark brown color, being more common in women of Hispanic origin. In this study, 27 men with melasma were evaluated clinically and histologically to compare their features with those of previous studies. Three patterns of localization were recognized, name...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4362.1988.tb02329.x
更新日期：1988-01-01 00:00:00
abstract：:The major characteristics of tricho-rhino-phalangeal syndrome (TRPS) include shortened and deviated digits, a typical facies with a pear-shaped nose, a long philtrum and slow-growing, fine, sparse hair. Cone-shaped digital epiphyses are seen on x-ray. A few patients with TRPS are mentally retarded. Associated endocrin...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4362.1979.tb01972.x
更新日期：1979-09-01 00:00:00
abstract：:A 64-year-old woman presented with erythematous, infiltrative plaques with a central atrophic area on both zygomatic regions. Several yellow-reddish papules were seen at the periphery of the plaques and showed an "apple-jelly" color on diascopy (Fig. 1). No visceral involvement was detected. The past medical history r...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4632.2008.03240.x
更新日期：2008-06-01 00:00:00
abstract：BACKGROUND:Warts are a common chronic skin disorder that can be cosmetically disfiguring and, depending on the location, cause inhibition of function. The presence of dozens of topical and systemic treatments for warts is a testament to the lack of a rapid, simple, uniformly effective, inexpensive, nonscarring, and pai...
journal_title：International journal of dermatology
pub_type： 临床试验,杂志文章
doi：10.1046/j.1365-4362.2001.01242.x
更新日期：2001-06-01 00:00:00
abstract：BACKGROUND:Castleman disease (CD) is a lymphoproliferative B-cell disease that is diagnosed from lymphoid hyperplasia with vascular proliferation. Symptoms may include fever, night sweats, and weight loss. Cutaneous manifestations often may go unnoticed since little has been described in the literature regarding them. ...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/ijd.15043
更新日期：2020-10-01 00:00:00
abstract：BACKGROUND:In recent years, the rare association of Sweet's syndrome with nontuberculous mycobacterial lymphadenitis has been reported. OBJECTIVE:To report the clinical, demographic, and bacteriologic data and association with Sweet's syndrome of 18 patients with scrofuloderma and scrofuloderma-like condition caused b...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1046/j.1365-4362.2002.01362.x
更新日期：2002-01-01 00:00:00
abstract：:Two patients with premycotic poikiloderma developed one squamous cell carcinoma each. A review of the literature reveals 28 reported cases of this association, but in 26 of these the patient had been exposed to carcinogens. Our patients had no history of exposure to carcinogenic agents. In both our cases, the squamous...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4362.1986.tb03424.x
更新日期：1986-07-01 00:00:00
abstract：BACKGROUND:Photodynamic therapy (PDT) is a non-surgical method for treating non-melanoma skin cancer and precancerous lesions which involves the activation of a photosensitizer by visible light to produce activated oxygen species within target cells, resulting in the destruction of the latter. The present study evaluat...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4632.2010.04700.x
更新日期：2011-03-01 00:00:00
abstract：:Clouston's syndrome is an ectodermal dysplasia characterized by dystrophic nails, alopecia, and palmoplantar hyperkeratosis. Alopecia is due to decrease in number and degree of maturation of the hair follicles. Tretinoin is a mitogen by itself and also enhances the absorption of minoxidil which acts by enlarging the m...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4632.2009.03907.x
更新日期：2009-02-01 00:00:00
abstract：BACKGROUND:'"Inflammatory vitiligo" cases with clear lichenoid infiltrates have been reported. However, the inflammatory nature of common vitiligo has not gained wide acceptance because of its benign appearance and scanty cellular infiltrates. We have observed in our patients a few lesions with mild erythema, scaling a...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4632.2008.03672.x
更新日期：2008-07-01 00:00:00
abstract：BACKGROUND:Prurigo pigmentosa (PP), a rare inflammatory disease of the skin, is mostly reported in the ethnic Japanese population. Its pathogenesis remains unclear. The chronic and recurrent nature of PP implies a possible role of viral infection in the pathogenesis. The anti-inflammatory mechanism of doxycycline, whic...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4632.2010.04625.x
更新日期：2011-01-01 00:00:00
abstract：BACKGROUND:Associations between vitamin D deficiency and a broad variety of independent diseases, including several bone diseases, various types of cancer, autoimmune diseases, hypertension, and cardiovascular disease, have been suggested. It is therefore important to detect and treat vitamin D deficiency in high-risk ...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/ijd.13119
更新日期：2016-09-01 00:00:00
abstract：BACKGROUND:The aim was to examine cadexomer iodine paste in a comparative clinical trial. METHODS:A 12-week, randomized, open, controlled, multicenter, multinational trial in patients with exudating, venous leg ulcers of cadexomer iodine paste (Iodosorb/Iodoflex), hydrocolloid dressing (Duoderm E, Granuflex E), or par...
journal_title：International journal of dermatology
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1046/j.1365-4362.1998.00415.x
更新日期：1998-05-01 00:00:00
abstract：:In a survey of clinical trials concerning the efficacy of short-contact therapy with anthralin in psoriasis vulgaris, focusing principally on methodologic issues, twenty-four papers published between January 1982 and December 1989, in English, French, and Italian, were selected. Nine of 24 papers reported on more than...
journal_title：International journal of dermatology
pub_type： 杂志文章,meta分析
doi：10.1111/j.1365-4362.1992.tb03254.x
更新日期：1992-02-01 00:00:00
abstract：BACKGROUND:Papulonecrotic tuberculid is a rarely reported cutaneous reaction to the mycobacterium bacillus. It is most often encountered in association with tuberculosis. The clinical and histologic picture of the entity is a distinctive one, but the etiology of the disease process is uncertain. Therapy directed agains...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4362.1994.tb01537.x
更新日期：1994-02-01 00:00:00
abstract：OBJECTIVE:To report three cases of mycosis fungoides with milia formation in the regressing lesions. PATIENTS AND SETTING:Dermatology clinic of a university hospital (referral center). Three patients with mycosis fungoides with body surface involvement of 10% in one case (stage IIb) and exceeding 30% in two cases (sta...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4632.2004.01944.x
更新日期：2004-12-01 00:00:00
abstract：:Scleromyxedema is a rare disease characterized by papular mucinous deposits, dermal fibroblast proliferation, and a monoclonal paraproteinemia. Its chronic course tends to be complicated by gastrointestinal, muscular, pulmonary, and neurologic disorders. We review the literature to identify the common systemic manifes...
journal_title：International journal of dermatology
pub_type： 杂志文章,评审
doi：10.1046/j.1365-4362.2003.01565.x
更新日期：2003-01-01 00:00:00
abstract：BACKGROUND:Altered levels of sex hormones have been observed in many autoimmune disorders, but there is no considerable data about pemphigus. The aim of this study is to compare serum total and free prolactin and dehydroepiandrosterone sulfate (DHEAS) levels between patients with pemphigus and healthy controls and to d...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/ijd.13199
更新日期：2016-06-01 00:00:00
abstract：BACKGROUND:Targeted therapies and immunotherapies are increasingly prescribed, but classic chemotherapy agents are still highly used in cancer treatment. Both therapies, the old and the new, are associated with cutaneous adverse events (CAEs) that can cause treatment interruptions or reduce the quality of life of patie...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/ijd.15081
更新日期：2021-02-01 00:00:00
abstract：BACKGROUND:Tattoos have reached broadening mainstream acceptance. Medical professional societies have noted that tattoos may co-occur with high risk behaviors. METHODS:Using a variety of statistical models applied to a sample of 2,008 adults residing in the United States via Amazon's Mechanical Turk, we estimate the a...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/ijd.14372
更新日期：2019-07-01 00:00:00
abstract：:Skin lesions are frequent in human T-cell lymphotropic virus type 1 (HTLV-1) infection and may constitute an alert for the diagnosis of this condition. The most severe skin diseases related to this virus are adult T-cell leukemia/lymphoma (ATLL), an aggressive form of leukemia/lymphoma that fails to respond to chemoth...
journal_title：International journal of dermatology
pub_type： 杂志文章,评审
doi：10.1111/j.1365-4632.2010.04568.x
更新日期：2010-10-01 00:00:00
abstract：BACKGROUND:The 180-kDa transmembrane hemidesmosomal protein (BPAG2) has been identified as an important autoantigen in bullous pemphigoid (BP). Using the NC16A domain as the antigenic target, a highly sensitive and specific enzyme-linked immunosorbent assay (ELISA) for the detection of autoantibodies to BP180 was devel...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4632.2008.03473.x
更新日期：2008-03-01 00:00:00
abstract：:The occurrence of erythema nodosum leprosum among leprosy patients treated with diamino diphenyl sulfone in an endemic area is not rare, unlike in the leprosy patients treated at Lagos University Teaching Hospital. Two Nigerian patients with this disease are described, in whom this rarity was seen. Recurrent monthly f...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4362.1975.tb00160.x
更新日期：1975-11-01 00:00:00
abstract：BACKGROUND:Vitiligo is a common, acquired condition of unknown etiology. The only practical treatment for patients with vitiligo is psoralen ultraviolet A (PUVA). No satisfactory method is available to measure the influence of certain factors on the therapeutic response. METHODS:Twenty-nine patients with generalized v...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4362.1995.tb01571.x
更新日期：1995-03-01 00:00:00
abstract：:Acanthosis nigricans (AN) and scleredema are two skin conditions that have been reported in association with diabetes mellitus. Few cases associating scleredema and AN have been reported. A literature search did not reveal any reports of diabetic patients developing AN on top of a scleredema plaque. Here we report a p...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4632.2004.02003.x
更新日期：2005-01-01 00:00:00
abstract：BACKGROUND:Human T-cell lymphotrophic virus type 1 (HTLV-1)-induced lymphoproliferative disease occurs in approximately 3-5% of people in endemic areas who have been HTLV-1 positive for decades. Lymphoproliferative disease may present as four subtypes, including an acute adult T-cell leukemia/lymphoma (ATLL), an aggres...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1046/j.1365-4362.2000.00937.x
更新日期：2000-11-01 00:00:00
abstract：BACKGROUND:Reed's nevi are distinguished from Sptiz tumors by their significant melanogenesis and growth pattern. They may be confused with melanoma on clinical and histologic grounds. CASE REPORT:An unusual case in which multiple agminated Reed's nevi mimicked acral lentiginous malignant melanoma in an African-Americ...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4362.1993.tb04268.x
更新日期：1993-04-01 00:00:00
abstract：BACKGROUND:In recent years, an unusual biologic behavior of Merkel cell tumor (MCT) has been noted. In some patients, the tumor was indolent and well controlled by therapy, while in others it was lethal in a few months. Even though the majority of the reported cases are between these two biologic extremes, it seems evi...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4362.1993.tb01470.x
更新日期：1993-05-01 00:00:00
abstract：BACKGROUND:Though any drug can be a potential cause of such hypersensitivity reactions, paracetamol, an over-the-counter drug used extensively as an analgesic and antipyretic agent, is considered to be relatively safe, with hepatotoxicity as a major adverse effect only in large doses. MATERIALS AND METHODS:We report a...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/ijd.12355
更新日期：2014-08-01 00:00:00
