A modified sub-second fast-STEAM sequence incorporating bipolar gradients for in vivo diffusion imaging.

Abstract:

:A modified high-speed stimulated-echo acquisition mode (STEAM) diffusion sequence (90 degrees-TE/2-90 degrees-TM-[alpha-TE/2-STE]n) incorporating bipolar diffusion gradients that are less sensitive to macroscopic motion-induced artifacts is presented. Diffusion encoding was performed only during the first echo interval (TE1) with bipolar gradients that were implemented on all three mutually orthogonal axes. Calibration measurements on phantoms filled with water, isopropanol, and dimethyl sulfoxide yielded apparent diffusion coefficients (ADC) consistent with published values. Non-ECG-triggered in vivo images acquired on rat brain with relatively high b values (approximately 450 s/mm2) indicated minimal motion artifacts. Evaluated ADCs averaged over the cortex, left mid-brain, right mid-brain, regions yielded (0.91 +/- 0.02), (1.06 +/- 0.02), (1.01 +/- 0.03) x 10(-3) mm2s-1, respectively.

journal_name

Magn Reson Med

authors

Yongbi MN,Ding S,Dunn JF

doi

10.1002/mrm.1910350620

subject

Has Abstract

pub_date

1996-06-01 00:00:00

pages

911-6

issue

6

eissn

0740-3194

issn

1522-2594

journal_volume

35

pub_type

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