Natural scenes viewing alters the dynamics of functional connectivity in the human brain.

Abstract:

:Spontaneous fMRI fluctuations are organized in large-scale spatiotemporal structures, or resting-state networks (RSN). However, it is unknown how task performance affects RSN dynamics. We use MEG to measure slow (∼0.1 Hz) coherent fluctuations of band-limited power (BLP), a robust correlate of RSN, during rest and movie observation and compare them to fMRI-RSN. BLP correlation, especially in α band, dropped in multiple RSN during movie although overall topography was maintained. Variability of power correlation increased in visual occipital cortex, and transient decrements corresponded to scenes perceived as "event boundaries." Additionally, stronger task-dependent interactions developed between vision and language networks in θ and β bands, and default and language networks in γ band. The topography of fMRI connectivity and relative changes induced by the movie were well matched to MEG. We conclude that resting-state and task network interactions are clearly different in the frequency domain despite maintenance of underlying network topography.

journal_name

Neuron

journal_title

Neuron

authors

Betti V,Della Penna S,de Pasquale F,Mantini D,Marzetti L,Romani GL,Corbetta M

doi

10.1016/j.neuron.2013.06.022

subject

Has Abstract

pub_date

2013-08-21 00:00:00

pages

782-97

issue

4

eissn

0896-6273

issn

1097-4199

pii

S0896-6273(13)00538-2

journal_volume

79

pub_type

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