Temporal resolution in olfaction II: time course of recovery from adaptation in lobster chemoreceptor cells.

abstract：:Proteinase-activated receptors (PARs) have a unique activation mechanism in that a proteolytically exposed N-terminal region acts as a tethered ligand. A potential impact of PAR on sensory processing has not been fully examined yet. Here we report that synthetic peptides with sequences corresponding to PAR ligands enh...

journal_title：Journal of neurophysiology

authors： Fujita T,Liu T,Nakatsuka T,Kumamoto E

更新日期：2009-07-01 00:00:00

abstract：:1. Spontaneous synaptic activity in networks formed by dissociated neurons from embryonic rat midbrain was analyzed in tight seal whole cell recordings. 2. Application of furosemide (0.5 mM) to the cell and its surrounding area increased the frequency of spontaneous synaptic currents. Incubation of the culture with fu...

journal_title：Journal of neurophysiology

authors： Jarolimek W,Brunner H,Lewen A,Misgeld U

更新日期：1996-06-01 00:00:00

abstract：:When a monkey attends to, remembers, and looks toward targets, the activity of some neurons in the lateral intraparietal area (LIP) changes. We recorded from isolated neurons during both a spatial and a shape match-to-sample task to examine and characterize voluntary active processes in LIP. Many LIP neurons show spat...

journal_title：Journal of neurophysiology

authors： Sereno AB,Amador SC

更新日期：2006-02-01 00:00:00

abstract：:In this study, the representation of taste in the orbitofrontal cortex was investigated to determine whether or not a pleasant and an aversive taste have distinct or overlapping representations in this region. The pleasant stimulus used was sweet taste (1 M glucose), and the unpleasant stimulus was salt taste (0.1 M N...

journal_title：Journal of neurophysiology

authors： O'Doherty J,Rolls ET,Francis S,Bowtell R,McGlone F

更新日期：2001-03-01 00:00:00

abstract：:Hippocampal interneurons are excited via serotonin-gated ion channels. J. Neurophysiol. 78: 2493-2502, 1997. Serotonergic neurons of the median raphe nucleus heavily innervate hippocampal GABAergic interneurons located in stratum radiatum of area CA1, suggesting that this strong subcortical projection may modulate int...

journal_title：Journal of neurophysiology

authors： McMahon LL,Kauer JA

更新日期：1997-11-01 00:00:00

abstract：:Morphine remains widely used in clinical settings due to its potent analgesic properties. However, one of the gravest risks of all opioids is their ability to induce respiratory depression and subsequent brain hypoxia that can lead to coma and death. Due to these life-threatening effects, our goal was to examine the e...

journal_title：Journal of neurophysiology

authors： Solis E Jr,Afzal A,Kiyatkin EA

更新日期：2018-11-01 00:00:00

abstract：:Fear conditioning involves the transmission of sensory stimuli to the amygdala from the thalamus and cortex. These input synapses are prime candidates for sites of plasticity critical to the learning in fear conditioning. Because N-methyl-D-aspartate (NMDA)-dependent mechanisms have been implicated in fear learning, w...

journal_title：Journal of neurophysiology

authors： Weisskopf MG,LeDoux JE

更新日期：1999-02-01 00:00:00

abstract：:Pentobarbital, a general anesthetic, has received extensive study for its ability to potentiate inhibition at GABA(A) subtype of receptors for GABA. Using whole cell current-clamp techniques and bath applications, we determined the effects of pentobarbital and GABA receptor antagonists on the membrane properties and t...

journal_title：Journal of neurophysiology

authors： Wan X,Puil E

更新日期：2002-12-01 00:00:00

abstract：:Synaptic interactions between nearby excitatory and inhibitory neurons in the neocortex are thought to play fundamental roles in sensory processing. Here, we have combined optogenetic stimulation, whole cell recordings, and computational modeling to define key functional microcircuits within layer 2/3 of mouse primary...

journal_title：Journal of neurophysiology

authors： Avermann M,Tomm C,Mateo C,Gerstner W,Petersen CC

更新日期：2012-06-01 00:00:00

abstract：:Bladder and erectile dysfunction are common urologic complications of diabetes and are associated with reduced parasympathetic autonomic control. To determine whether disruption of ganglionic neurotransmission contributes to the loss of function, we investigated synaptic transmission at parasympathetic, major pelvic g...

journal_title：Journal of neurophysiology

authors： Tompkins JD,Vizzard MA,Parsons RL

更新日期：2013-02-01 00:00:00

abstract：:1. Single-electrode voltage-clamp recordings were made from CA3 pyramidal cells in organotypic hippocampal slice cultures for measurement of membrane currents underlying both the gamma-aminobutyric acid (GABA)-mediated, Cl- -dependent inhibitory postsynaptic potential (IPSC), evoked in response to stimulation of the m...

journal_title：Journal of neurophysiology

authors： Thompson SM,Gähwiler BH

更新日期：1989-03-01 00:00:00

abstract：:Earlier studies suggest that the inferior temporal (IT) cortex of the monkey plays a key role in color discrimination. Here, we examined the quantitative relationship between color judgment in monkeys and the responses of color-selective neurons in the anterior part of the IT cortex (area TE) by comparing neuronal act...

journal_title：Journal of neurophysiology

authors： Matsumora T,Koida K,Komatsu H

更新日期：2008-12-01 00:00:00

abstract：:1. The neurophysiological basis for the sensation of prickle evoked by contact of some fabrics with the skin is reported. 2. Single-unit sensory nerve recordings from the rabbit saphenous nerve were used to identify the receptors responsible for fabric-evoked prickle. These recordings showed that all low-threshold mec...

journal_title：Journal of neurophysiology

authors： Garnsworthy RK,Gully RL,Kenins P,Mayfield RJ,Westerman RA

更新日期：1988-04-01 00:00:00

abstract：:In recent years a small number of studies have applied functional imaging techniques to investigate visual responses in the human superior colliculus (SC), but few have investigated its oculomotor functions. Here, in two experiments, we examined activity associated with endogenous saccade preparation. We used 3-T fMRI...

journal_title：Journal of neurophysiology

authors： Furlan M,Smith AT,Walker R

更新日期：2015-08-01 00:00:00

abstract：:In the main olfactory bulb, several populations of granule cells (GCs) can be distinguished based on the soma location either superficially, interspersed with mitral cells within the mitral cell layer (MCL), or deeper, within the GC layer (GCL). Little is known about the physiological properties of superficial GCs (sG...

journal_title：Journal of neurophysiology

authors： Heinbockel T,Hamilton KA,Ennis M

更新日期：2007-04-01 00:00:00

abstract：:Microstimulation within the motor regions of the spinal cord is often assumed to activate motoneurons and propriospinal neurons close to the electrode tip. However, previous work has shown that intraspinal microstimulation (ISMS) in the gray matter activates sensory afferent axons as well as alpha-motoneurons (MNs). H...

journal_title：Journal of neurophysiology

authors： Gaunt RA,Prochazka A,Mushahwar VK,Guevremont L,Ellaway PH

更新日期：2006-12-01 00:00:00

abstract：:Studies on generalization show the nature of how learning is encoded in the brain. Previous studies have shown rather limited generalization of dynamics learning across changes in movement direction, a finding that is consistent with the idea that learning is primarily local. In contrast, studies show a broader patter...

journal_title：Journal of neurophysiology

authors： Mattar AA,Ostry DJ

更新日期：2010-07-01 00:00:00

abstract：:The completion of an antisaccade (i.e., a nonstandard task) lengthens the reaction time (RT) of a subsequent prosaccade: a behavioral phenomenon termed the unidirectional prosaccade switch-cost. One explanation for the unidirectional prosaccade switch-cost is suppressing a stimulus-driven prosaccade during the precedi...

journal_title：Journal of neurophysiology

authors： Weiler J,Heath M

更新日期：2014-11-01 00:00:00

abstract：:It was recently shown that repeated heat stimulation, using brief contacts (<1 s) with a preheated thermode at sufficiently short interstimulus intervals (ISIs <5 s) and high temperatures (> or =51 degrees C), will elicit in humans a sensation of rapidly augmenting "second" (burning) pain with only a weak "first" (sha...

journal_title：Journal of neurophysiology

authors： Craig AD,Andrew D

更新日期：2002-04-01 00:00:00

abstract：:Response properties of cells in the infragranular layers of cortical area 17 of the cat were examined in the absence of input from supragranular layers. Supragranular activity was silenced either reversibly by cooling the surface of cortex or permanently by making a cryogenic lesion of the supragranular layers. Visual...

journal_title：Journal of neurophysiology

authors： Schwark HD,Malpeli JG,Weyand TG,Lee C

更新日期：1986-10-01 00:00:00

abstract：:Acetylcholine increases intracellular calcium of arterial chemoreceptor cells of adult cats. J. Neurophysiol. 78: 2388-2395, 1997. Several neurotransmitters have been reported to play important roles in the chemoreception of the carotid body. Among them acetylcholine (ACh) appears to be involved in excitatory processe...

journal_title：Journal of neurophysiology

authors： Shirahata M,Fitzgerald RS,Sham JS

更新日期：1997-11-01 00:00:00

abstract：:1. A novel approach for analyzing transients in passive structures called "the method of moments" is introduced. It provides, as a special case, an analytic method for calculating the time delay and speed of propagation of electrical signals in any passive dendritic tree without the need for numerical simulations. 2. ...

journal_title：Journal of neurophysiology

authors： Agmon-Snir H,Segev I

更新日期：1993-11-01 00:00:00

abstract：:Neural oscillations are observed ubiquitously in the mammalian brain, but their stability is known to be rather variable. Some oscillations are tonic and last for seconds or even minutes. Other oscillations appear as unstable bursts. Likewise, some oscillations rely on excitatory AMPAergic synapses, but others are GAB...

journal_title：Journal of neurophysiology

authors： Peterson EJ,Voytek B

更新日期：2020-07-01 00:00:00

abstract：:The brain can precisely encode the temporal relationship between tactile inputs. While behavioural studies have demonstrated precise interfinger temporal judgments, the underlying neural mechanism remains unknown. Computationally, two kinds of neural responses can act as the information source. One is the phase-locked...

journal_title：Journal of neurophysiology

authors： Kuroki S,Watanabe J,Nishida S

更新日期：2016-03-01 00:00:00

abstract：:Caenorhabditis elegans responds to chemical cues using a small number of chemosensory neurons that detect a large variety of molecules in its environment. During chemotaxis, C. elegans biases its migration in spatial chemical gradients by lengthening (/shortening) periods of forward movement when it happens to be movi...

journal_title：Journal of neurophysiology

authors： Luo L,Gabel CV,Ha HI,Zhang Y,Samuel AD

更新日期：2008-05-01 00:00:00

abstract：:Exposure to odorants results in a rapid (<10 s) reduction in odor-evoked activity in the rat piriform cortex despite relatively maintained afferent input from olfactory bulb mitral cells. To further understand this form of cortical plasticity, a detailed analysis of its odor specificity was performed. Habituation of o...

journal_title：Journal of neurophysiology

authors： Wilson DA

更新日期：2000-01-01 00:00:00

abstract：:If a laterally displacing prism is placed in front of one eye of a person or monkey with the other eye occluded, they initially will point to one side of a target that is located directly in front of them. Normally, people and monkeys adapt easily to the displaced vision and correct their aim after a few trials. If th...

journal_title：Journal of neurophysiology

authors： Baizer JS,Kralj-Hans I,Glickstein M

更新日期：1999-04-01 00:00:00

abstract：:The generation of a behaviorally relevant cue to the speed of objects around us is critical to our ability to navigate safely within our environment. However, our perception of speed is often distorted by prevailing conditions. For instance, as luminance is reduced, our perception of the speed of fast-moving patterns ...

journal_title：Journal of neurophysiology

authors： Hammett ST,Smith AT,Wall MB,Larsson J

更新日期：2013-08-01 00:00:00

abstract：:Based on kinematic properties and distinct substrates, there are different classes of eyelid movement described as eyeblinks. We investigate whether the eyelid movements made in response to a conditioned stimulus (CS) are a category of eyelid movements distinct from blinks. Human subjects received 60 trials of classic...

journal_title：Journal of neurophysiology

authors： Schade Powers A,Coburn-Litvak P,Evinger C

更新日期：2010-02-01 00:00:00

abstract：:Brain-derived neurotrophic factor (BDNF) can potentiate synaptic release at newly developed frog neuromuscular junctions. Although this potentiation depends on extracellular Ca(2+) and reflects changes in acetylcholine release, little is known about the intracellular transduction or calcium signaling pathways. We have...

journal_title：Journal of neurophysiology

authors： Kleiman RJ,Tian N,Krizaj D,Hwang TN,Copenhagen DR,Reichardt LF

更新日期：2000-07-01 00:00:00