Abstract：
OBJECTIVE:The present study was undertaken to test the hypothesis that smoking induces peripheral endothelial dysfunction and altered function in central conduit arteries. METHODS:A total of 22 healthy volunteers (10 women and 12 men; mean age 25.3 +/- 5.8 years) were included. At baseline, brachial artery flowmediated dilatation (FMD), aortic stiffness index (ASI), aortic distensibility (AoD), and aortic elastic modulus (AoEM) of all subjects were measured. On the 2nd day, the subjects were assigned to smoke either 1 light (0.6 mg of nicotine, 8 mg of tar, and 9 mg of carbon monoxide) or 1 regular cigarette (0.9 mg of nicotine, 12 mg of tar, and 12 mg of carbon monoxide) and the measurements were repeated for all subjects 20 minutes following smoking. After 15 days, the subjects were assigned to smoke 1 cigarette of the type that was not smoked on the 2nd day, and the same measurements were performed 20 minutes after smoking. RESULTS:In response to smoking 1 light cigarette, FMD values declined from 15.0 +/- 6.8% to 9.1 +/- 2.9% (P = 0.002). After smoking 1 regular cigarette, FMD values declined from 15.0 +/- 6.8% to 9.4 +/- 4.8% (P= 0.002). Aortic elasticity and left ventricular diastolic functions (LVDF) were significantly impaired by both types of cigarettes. CONCLUSION:Smoking light cigarettes has similar acute detrimental effects on FMD, LVDF, ASI, AoD, and AoEM as regular cigarettes.
journal_name
Acta Cardioljournal_title
Acta cardiologicaauthors
Ciftçi O,Günday M,Calişkan M,Güllü H,Güven A,Müderrisoğlu Hdoi
10.1080/ac.68.3.2983419subject
Has Abstractpub_date
2013-06-01 00:00:00pages
255-61issue
3eissn
0001-5385issn
1784-973Xjournal_volume
68pub_type
杂志文章,随机对照试验abstract：OBJECTIVES:Angiotensin-converting enzyme (ACE) is a key enzyme in the production of angiotensin II and thus may participate in the modulation of cardiac growth. The cloning of the ACE gene has made it possible to identify a deletion (D)-insertion (I) polymorphism that appears to affect the level of serum ACE activity. ...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.2143/AC.60.2.2005025
更新日期：2005-04-01 00:00:00
abstract：:The present study aims at evaluating the acute hemodynamic effects of external and internal (3 and 15 mA) pacing on 30 patients with severe cardiac failure. The global and regional ejection fraction were calculated by repeated radionuclide ventriculography at rest (control) and during increasing pacing rates. Blood pr...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：OBJECTIVE:Cardiac resynchronization therapy (CRT), combined with optimal medical therapy (OMT), is an established treatment for patients with advanced chronic heart failure (ACHF). In ACHF, carvedilol at the dose used in clinical trials, reduces morbidity and mortality. However, patients often do not tolerate the drug ...
journal_title：Acta cardiologica
pub_type： 临床试验,杂志文章
doi：10.1080/ac.66.5.2131081
更新日期：2011-10-01 00:00:00
abstract：:Background: Quality indicators (QIs) are used to measure and evaluate quality of care. However, QIs to evaluate care for HF patients in general practice in Belgium are lacking. Therefore, this study aimed to determine which QIs, rooted in the electronic health record (EHR), are useful to monitor quality of care for pa...
journal_title：Acta cardiologica
pub_type： 共识发展会议,杂志文章,评审
doi：10.1080/00015385.2018.1492659
更新日期：2019-08-01 00:00:00
abstract：OBJECTIVE:The aim of this paper was to investigate the association between levels of HO-1 expression and angiographic morphology as well as the quantity of coronary lesions in patients with coronary heart disease (CHD). METHODS:110 patients with CHD were diagnosed by coronary angiography which contained coronary lesio...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.2143/AC.61.3.2014831
更新日期：2006-06-01 00:00:00
abstract：OBJECTIVE:This study was performed to assess whether post-stress and rest functional parameters, as measured by gated-SPECT, provide additional predictive value for long-term prognosis, over clinical and perfusion data in patients (pts.) with low left ventricular ejection fraction (LVEF). METHODS:647 consecutive pts. ...
journal_title：Acta cardiologica
pub_type： 临床试验,杂志文章
doi：10.2143/AC.59.1.2005154
更新日期：2004-02-01 00:00:00
abstract：:During inflammation, several cell types synthesize and secrete phospholipase A2 that catalyses lipid oxidation in LDL. Myeloperoxidase, a haeme protein secreted by activated phagocytes, oxidizes L-tyrosine to a tyrosyl radical that is a physiological catalyst for the initiation of lipid oxidation in LDL. Lipid oxidati...
journal_title：Acta cardiologica
pub_type： 杂志文章,评审
doi：10.2143/AC.59.5.2005219
更新日期：2004-10-01 00:00:00
abstract：:We present a 64-year-old woman who was brought to the emergency department after suffering a motor vehicle accident, involving multiple soft tissue and bone trauma. Even though she was free from cardiovascular symptoms for the last three years, her past medical history of aorto-coronary bypass surgery prompted preoper...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.2143/AC.58.2.2005271
更新日期：2003-04-01 00:00:00
abstract：:The purpose of the present study was to determine whether the cardiorespiratory variables measured during an exercise test with a continuously increasing workload (ramp) protocol are reproducible and to compare them to the values obtained with a step-wise incremental (James) protocol. Twenty normal adolescents and you...
journal_title：Acta cardiologica
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1996-01-01 00:00:00
abstract：:Thromboembolic events are major causes of morbidity and mortality in patients with native heart valve disease and artificial heart valves. Oral anticoagulation can reduce these complications. The indication for and intensity of oral anticoagulation depends on both, the risk for thromboembolic events and the risk of he...
journal_title：Acta cardiologica
pub_type： 杂志文章,评审
doi：
更新日期：1996-01-01 00:00:00
abstract：UNLABELLED:OBJECTIVE; ; The objective of this study was to identify developmental changes in vascular smooth muscle cells (VSMC) during aneurysm formation using an elastase-induced rabbit carotid artery aneurysm model. METHODS:- Aneurysms were induced in carotid arteries of rabbits by exposure to elastase. Tissues fro...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.1080/ac.65.5.2056235
更新日期：2010-10-01 00:00:00
abstract：BACKGROUND:The renin-angiotensin-aldosterone system (RAAS) plays an important role in blood pressure regulation, left ventricular and vascular structure. Some hypertensive patients develop left ventricular dilatation and heart failure symptoms while others are relatively less affected. The purpose of our study was to d...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.2143/AC.61.1.2005137
更新日期：2006-02-01 00:00:00
abstract：:Introduction Strength exercises influence the cardiovascular system by promoting autonomic adjustments induced by the increased metabolic demand and consequent increase in local blood flow. However, it is unclear whether there are differences between upper and lower limbs. We aimedto evaluate recovery of cardiac auton...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.1080/00015385.2017.1335454
更新日期：2017-08-01 00:00:00
abstract：:In order to study the arterial blood supply of the sinus atrial node in the Dog, the authors have performed the post-mortem injection of the arterial branches going to this node. They observed 65 cases and they came to the following conclusions: in 31 cases (47.7%) the sinus atrial node is supplied by the artery of th...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：
更新日期：1975-01-01 00:00:00
abstract：OBJECTIVE:Smoking mentholated cigarettes inhibits the metabolism of nicotine and increases systemic exposure to cigarette smoke toxins. However, the possible effects of smoking mentholated cigarettes on coronary microvascular functions are unknown. We sought to investigate whether smoking mentholated cigarettes impairs...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.2143/AC.63.2.2029518
更新日期：2008-04-01 00:00:00
abstract：:The authors present a case of permanent atrial standstill with syncopal attacks, in a patient with chronic Chagas' Heart Disease. The recognition of this dysrhythmia was based upon the conventional and intracavity electrocardiographic tracings in addition to phonomecanographic and hemodynamic data. The recording of th...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：
更新日期：1975-01-01 00:00:00
abstract：BACKGROUND:There are few studies detailing the prevalence of prehypertension and hypertension in India. METHODS:Men and women, over 25 years of age were included. After completion of a dietitian-administered questionnaire followed evaluation by a physician, physical examination and blood pressure measurement. Cross-se...
journal_title：Acta cardiologica
pub_type： 杂志文章,多中心研究
doi：10.1080/ac.66.1.2064964
更新日期：2011-02-01 00:00:00
abstract：:Diffuse intra-alveolar haemorrhage is a rare complication of thrombolytic therapy (TT). We report a patient who developed haemoptysis due to pulmonary haemorrhage. This diagnosis should be considered in any patients with respiratory distress, diffuse pulmonary infiltrates, and haemoptysis and otherwise unexplained dec...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.2143/AC.59.3.2005194
更新日期：2004-06-01 00:00:00
abstract：:The main reason for the pacemaker syndrome during VVI pacing is the existence of ventriculoatrial conduction (V-AC). Twenty-five patients with a permanent DDD pacemaker and ventriculoatrial conduction were included in the study. IN those patients the hemodynamic changes were evaluated in relation to ANP plasma concent...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：
更新日期：1997-01-01 00:00:00
abstract：:We present the case of a young woman who developed a cerebrovascular accident due to a spontaneous internal carotid artery dissection. We stress the importance of clinical clues to diagnosis: ipsilateral facial pain and a partial Horner's syndrome are the most frequent clinical manifestations. Compared to patients wit...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.2143/AC.62.5.2023422
更新日期：2007-10-01 00:00:00
abstract：:The increasing number of amateur sportsmen enhances the need for a correct evaluation of subjects suspected of overt and mild cardiac disease. Out of 4000 athletes, 72 subjects were clinically preselected by the sport doctor during an annual routine examination. They were studied with mono and 2D echo, pulsed color (P...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:The combination of coarctation of the aorta in the presence of severe aortic insufficiency poses a serious clinical problem. Although successful single- and two-stage repair for combined coarctation in the presence of severe aortic regurgitation has been described, the surgical management of this lesion remains partic...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：:Electroconvulsive therapy (ECT) is used frequently in psychiatric practice and various electrocardiographic (ECG) changes have been described during ECT. QT dispersion (defined as maximal QT interval minus minimal QT interval) as assessed on the surface electrocardiogram has been demonstrated to reflect regional inhom...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：:We report the M-mode and two-dimensional echocardiographic findings in a patient with familial amyloidosis. The diagnosis was made by the clinical picture and histologic evidence of amyloid in peripheral nerve biopsy. Though the patient had no clinical sign of heart failure, extensive involvement of the heart was demo...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：
更新日期：1981-01-01 00:00:00
abstract：OBJECTIVE:Results of many studies show that apolipoprotein B (apo B) is a better marker of risk of vascular disease than other lipid markers including LDL and HDL-cholesterol and triglycerides. We investigated the association between two infectious agents: C. pneumoniae and H. pylori, known to have an atherogenic effec...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.2143/AC.60.6.2004930
更新日期：2005-12-01 00:00:00
abstract：OBJECTIVE:The European Society of Cardiology designated 2008 as the year of imaging. However, despite the intense focus on the many types of imaging and the relative benefits of each one, the optimal modalityfor the diagnosis of coronary artery disease remains controversial. Among the currently available techniques, co...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.1080/ac.66.2.2071253
更新日期：2011-04-01 00:00:00
abstract：:The optimal management of high-risk patients requiring urgent or emergency noncardiac surgery when the options for further testing and evaluation are limited, is unclear. The focus of most of the literature, including the American College of Cardiology/American Heart Association guidelines, has been on patients underg...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.2143/AC.60.5.2004980
更新日期：2005-10-01 00:00:00
abstract：:A follow-up study was carried out in 98 patients with congestive cardiomyopathy using clinical data and M-mode echocardiography. 59 patients survived (mean follow-up period 18 months), 39 patients died (mean survival period 12.6 months). Median survival time was 3 years. Prognosis was unfavorably affected by ECG signs...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：
更新日期：1981-01-01 00:00:00
abstract：UNLABELLED:The aim of study was to determine the significance of the best echocardiographic parameters for assessing the severity of mitral regurgitation (MR). METHODS:The study population consisted of 107 patients, mean age 52 +/- 7 y with chronic isolated non-ischaemic MR. Quantification of the MR was performed usin...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.2143/AC.64.2.2036136
更新日期：2009-04-01 00:00:00
abstract：:Though cardiac involvement is a frequent finding in patients with Duchenne muscular dystrophy (DMD) at the wheel-chair-bound stage, left ventricular hypertrabeculation (LVHT) has not been reported. The patient is a 28-year-old male with the typical clinical features of end stage DMD. Since the age of 16 years he requi...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.2143/AC.60.4.2004996
更新日期：2005-08-01 00:00:00
