Diagnosis of renovascular disease by intra- and extrarenal Doppler scanning.

abstract：BACKGROUND:The debate on the association between nonphenacetin-containing combined analgesics and renal disease has lasted for several years. METHOD:A peer review committee of scientists, selected jointly by the regulatory authorities of Germany, Switzerland, and Austria and the pharmaceutical industry was asked to cr...

journal_title：Kidney international

authors： Feinstein AR,Heinemann LA,Curhan GC,Delzell E,Deschepper PJ,Fox JM,Graf H,Luft FC,Michielsen P,Mihatsch MJ,Suissa S,Van Der Woude F,Willich S

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:The new oral microemulsion formulation of cyclosporine (Neoral) possesses superior pharmacokinetics to the conventional formulation, Sandimmun (SIM), providing more complete and predictable absorption, and less pharmacokinetic variability. METHODS:The safety and tolerability of Neoral, together with the inc...

journal_title：Kidney international

authors： Keown P,Niese D

更新日期：1998-09-01 00:00:00

abstract：:The purpose of these studies was to clarify the basis of the relationship between the urine bicarbonate concentration and the urine minus blood PCO2 difference in alkaline urine (U-B PCO2) and hence shed light on factors that influence hydrogen ion secretion in the collecting duct in vivo. The U-B PCO2 was used to mon...

journal_title：Kidney international

authors： Tam SC,Goldstein MB,Stinebaugh BJ,Chen CB,Gougoux A,Halperin ML

更新日期：1981-11-01 00:00:00

abstract：:The purpose of this study was to explore risk factors affecting the incidence of chronic kidney disease (CKD) in general population. We conducted a 10-year follow-up study with 123 764 (male: 41 012, female: 82 752) adults aged 40 years and over who received community-based annual examinations. The primary outcome for...

journal_title：Kidney international

authors： Yamagata K,Ishida K,Sairenchi T,Takahashi H,Ohba S,Shiigai T,Narita M,Koyama A

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Chronic inflammation and oxidative stress are highly prevalent in patients with chronic kidney disease and end-stage renal disease (ESRD). These conditions contribute to high mortality rates associated with cardiovascular disease, the leading cause of death in this patient population. To our knowledge, no pr...

journal_title：Kidney international

authors： Pupim LB,Himmelfarb J,McMonagle E,Shyr Y,Ikizler TA

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:The relationship between low hematocrit and contrast-induced nephropathy has not been investigated. METHODS:Of 6,773 consecutive patients treated with percutaneous coronary intervention, contrast-induced nephropathy (an increase of >/=25% or >/=0.5 mg/dL in preprocedure serum creatinine, at 48 hours postpro...

journal_title：Kidney international

authors： Nikolsky E,Mehran R,Lasic Z,Mintz GS,Lansky AJ,Na Y,Pocock S,Negoita M,Moussa I,Stone GW,Moses JW,Leon MB,Dangas G

更新日期：2005-02-01 00:00:00

abstract：:The erythropoietin analogs have been an important advance for the treatment of the anemia of kidney disease, resulting in reduced need for blood transfusion and improved quality of life. Recent studies, however, have indicated risks associated with targeting higher levels of hemoglobin (Hb). As a result, in March 2007...

journal_title：Kidney international

authors： Fishbane S,Nissenson AR

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:The tissue renin-angiotensin system (RAS) may modulate the structural and functional changes that occur in the diabetic kidney. METHODS:Hypertensive transgenic (mREN-2)27 rat (TGR) that exhibit increased tissue renin expression were administered streptozotocin (STZ, diabetic) or citrate buffer (non-diabetic...

journal_title：Kidney international

authors： Kelly DJ,Wilkinson-Berka JL,Allen TJ,Cooper ME,Skinner SL

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:Lipid peroxidation impairs renal function. Aldosterone contributes to renal injury in the remnant kidney model. This study aimed to determine the effects of the antioxidant N-acetylcysteine (NAC) on renal function and aldosterone levels in chronic renal failure. METHODS:Adult male Wistar rats were submitted...

journal_title：Kidney international

authors： Shimizu MH,Coimbra TM,de Araujo M,Menezes LF,Seguro AC

更新日期：2005-11-01 00:00:00

abstract：:Mice chronically infected with the virus of lymphocytic choriomeningitis (LCM) develop immune complex glomerulonephritis. Others have shown that adoptive immunization of these mice by the i.p. injection of syngeneic immune spleen cells terminates the chronic viral carrier state. The present studies were designed to de...

journal_title：Kidney international

authors： Hoffsten PE,Villalobos R,Hill C,Klahr S

更新日期：1977-05-01 00:00:00

abstract：:In previous studies from this laboratory it has been shown that ATP-ase activity in situ in the glomerular basement membrane (GBM) is clearly reduced in rats rendered nephrotic after treatment with adriamycin (ADR). The question was raised whether this reduction of ATP-ase activity in the GBM is due to toxic activity ...

journal_title：Kidney international

authors： Bakker WW,Kalicharan D,Donga J,Hulstaert CE,Hardonk MJ

更新日期：1987-03-01 00:00:00

abstract：:To date direct evidence for the presence of a H-K-ATPase in the medulla comes from proton and potassium transport studies performed on K-restricted animals and K dependent ATP hydrolysis and Rb uptake in both normal and K-depleted animals. The present work examines K-dependent acidification in the medulla of rabbits o...

journal_title：Kidney international

authors： Curran KA,Hebert MJ,Cain BD,Wingo CS

更新日期：1992-11-01 00:00:00

abstract：:Unidirectional 32P-phosphate and 3H-mannitol fluxes were simultaneously measured, at two minutes intervals, in frog urinary bladders. The spontaneous or externally imposed transepithelial potential (PD) and short circuit current (SCC) were also recorded in most experiments. It was observed that: (1) Phosphate transfer...

journal_title：Kidney international

authors： Parisi M,Cancela L

更新日期：1988-01-01 00:00:00

abstract：:In this issue, McMahon et al. report that, by combining phenotypic, metabolomic, and genetic data, they could better detect chronic kidney disease at the early stages and provide insight into its pathobiology. The most significant findings of the study are that several urinary metabolites (e.g., glycine and histidine)...

journal_title：Kidney international

authors： Zhang G,Saito R,Sharma K

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Atherosclerotic vascular disease is the leading cause of death in patients with diabetes mellitus and end-stage renal disease. Advanced glycation end products (AGEs) are strongly suggested to be involved in the pathogenesis of atherosclerosis in these patients who also frequently experience infectious compli...

journal_title：Kidney international

authors： Sengoelge G,Födinger M,Skoupy S,Ferrara I,Zangerle C,Rogy M,Hörl WH,Sunder-Plassmann G,Menzel J

更新日期：1998-11-01 00:00:00

abstract：:Adhesion of calcium oxalate (CaOx) crystals to kidney cells may be a key event in the pathogenesis of kidney stones associated with marked hyperoxaluria. Previously, we found that 1,2,3,4,6-penta-O-galloyl-β-D-glucose (PGG), isolated from a traditional medicinal herb, reduced CaOx crystal adhesion to renal epithelial ...

journal_title：Kidney international

authors： Lee HJ,Jeong SJ,Lee HJ,Lee EO,Bae H,Lieske JC,Kim SH

更新日期：2011-03-01 00:00:00

abstract：:Chronic kidney disease (CKD) accelerates muscle protein degradation by stimulating the ubiquitin proteasome system through activation of the E3 ligases, Atrogin-1/MAFbx and MuRF-1. Forkhead transcription factors (FoxOs) can control the expression of these E3 ligases, but the contribution of individual FoxOs to muscle ...

journal_title：Kidney international

authors： Xu J,Li R,Workeneh B,Dong Y,Wang X,Hu Z

更新日期：2012-08-01 00:00:00

abstract：:Levels of components of the classical and alternative complement pathways and the activity of the C3 nephritic factor (C3NeF) were measured in serum specimens from patients with type I (subendothelial deposits) and type II (intramembranous dense deposits) membranoproliferative glomerulonephritis (MPGN) and the results...

journal_title：Kidney international

authors： Ooi YM,Vallota EH,West CD

更新日期：1976-01-01 00:00:00

abstract：:Intrauterine growth retardation (IUGR) aggravates the course of acute mesangioproliferative glomerulonephritis (GN) in the rat. Observational studies in children suggest that IUGR may be associated with a severe course of kidney diseases such as IgA nephropathy. We tested the hypothesis that IUGR leads to aggravation ...

journal_title：Kidney international

authors： Plank C,Ostreicher I,Hartner A,Marek I,Struwe FG,Amann K,Hilgers KF,Rascher W,Dötsch J

更新日期：2006-12-01 00:00:00

abstract：:The influence of transforming growth factor beta 1 (TGF-beta 1) and of dexamethasone on fibronectin (FN) synthesis of human renal tubular epithelial cells in culture (TEC) was studied. Cocultivation with TGF-beta 1 increased the steady state level of FN RNA within 24 to 48 hours. By PCR and Northern blotting it was fo...

journal_title：Kidney international

authors： Viedt C,Bürger A,Hänsch GM

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:Disorders that manifest hypokalemic metabolic alkalosis, such as Bartter's syndrome and Gitelman's syndrome, are caused by the malfunction of renal tubular electrolyte transporters. Bartter's syndrome may be linked to dysfunction of Na-K-2Cl cotransporter (NKCC2), renal outer medullary K channel (ROMK), or C...

journal_title：Kidney international

authors： Fukuyama S,Okudaira S,Yamazato S,Yamazato M,Ohta T

更新日期：2003-09-01 00:00:00

abstract：:Polyomavirus-associated nephropathy (PVAN) is a significant complication after kidney transplantation, often leading to premature graft loss. In order to identify antiviral responses of the renal tubular epithelium, we studied activation of the viral DNA and the double-stranded RNA (dsRNA) sensors Toll-like receptor 3...

journal_title：Kidney international

authors： Ribeiro A,Wörnle M,Motamedi N,Anders HJ,Gröne EF,Nitschko H,Kurktschiev P,Debiec H,Kretzler M,Cohen CD,Gröne HJ,Schlöndorff D,Schmid H

更新日期：2012-01-01 00:00:00

abstract：:Mineralocorticoid hormones stimulate Na+ absorption and K+ secretion by the cortical collecting tubule. There is good evidence that this stimulation involves increasing luminal membrane Na+ permeability and the turnover rate (or number) of the Na+-K+ pumps. These experiments were designed to examine whether mineraloco...

journal_title：Kidney international

authors： Stokes JB

更新日期：1985-10-01 00:00:00

abstract：:Sudden death is one of the more frequent causes of death for hemodialysis patients, but the underlying mechanisms, contribution of arrhythmia, and associations with serum chemistries or the dialysis procedure are incompletely understood. To study this, implantable loop recorders were utilized for continuous cardiac rh...

journal_title：Kidney international

authors： Roy-Chaudhury P,Tumlin JA,Koplan BA,Costea AI,Kher V,Williamson D,Pokhariyal S,Charytan DM,MiD investigators and committees.

更新日期：2018-04-01 00:00:00

abstract：:The monitoring of the levels of alloantibodies following transplantation might facilitate early diagnosis of chronic rejection (CR), the leading cause of renal allograft failure. Here, we used serial alloantibody surveillance to monitor patients with preoperative positive flow cytometric crossmatch (FCXM). Sixty-nine ...

journal_title：Kidney international

authors： Kimball PM,Baker MA,Wagner MB,King A

更新日期：2011-05-01 00:00:00

abstract：:Intravital multiphoton microscopy is a powerful tool to study kidney physiology in living animals. However, certain technical issues have curbed its usage to date, including limited depth of tissue penetration and high background emission of endogenous signals. Most previous studies have used the excitation range 700–...

journal_title：Kidney international

authors： Schuh CD,Haenni D,Craigie E,Ziegler U,Weber B,Devuyst O,Hall AM

更新日期：2016-03-01 00:00:00

abstract：:The clinical value of biocompatible peritoneal dialysis solutions is uncertain because of inconsistent findings in randomized controlled trials. A systematic review by Cho et al. examining 20 such trials suggests a beneficial effect on residual renal function. However, the finding is not robust and may relate to decre...

journal_title：Kidney international

authors： Blake PG,Jain AK,Yohanna S

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to examine the lipid abnormalities associated with urinary albumin excretion rate (UAER) in type 2 diabetic patients. METHODS:A total of 275 (122 men and 153 women; aged 60.6 +/- 11.1 years) patients were selected with stringent criteria to prevent confounders. Normoalbuminuria...

journal_title：Kidney international

authors： Tseng CH

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:Renal failure and toxic acute tubular necrosis (ATN) may be seen following exposure to a variety of therapeutic agents. Zoledronate (Zometa) is a new, highly potent bisphosphonate used in the treatment of hypercalcemia of malignancy. We report the first clinical-pathologic study of nephrotoxicity associated ...

journal_title：Kidney international

authors： Markowitz GS,Fine PL,Stack JI,Kunis CL,Radhakrishnan J,Palecki W,Park J,Nasr SH,Hoh S,Siegel DS,D'Agati VD

更新日期：2003-07-01 00:00:00

abstract：:IgA nephropathy is the most common primary glomerulonephritis worldwide. Its frequent coexistence with inflammatory, infectious, or malignant processes raises the possibility of a pathologic rather than coincidental association. Major strides have been made to elucidate the underlying pathophysiologic events that culm...

journal_title：Kidney international

authors： Saha MK,Julian BA,Novak J,Rizk DV

更新日期：2018-10-01 00:00:00