Effect of a research nurse on patient enrollment in a clinical study.

Abstract:

OBJECTIVES:To assess the effect of adding a shared research nurse on patient enrollment in an ongoing clinical study. DESIGN:Before/after comparison of recruitment rates and consent rates involving patients eligible for a study of blood culture collection strategies for methods on the detection of bacteremia and determination of inter-rater agreement regarding study eligibility between the research nurse and primary investigator. SETTING:An urban pediatric emergency department (ED). PARTICIPANTS:Patients presenting to the ED between February 1, 1991, and February 1, 1993, with suspected bacteremia. INTERVENTION:Addition of a research nurse to the study group to identify, educate, and enroll eligible study patients. MAIN OUTCOME MEASURE:Patient enrollment rates. RESULTS:Successful enrollment of eligible study patients was 14% (40/281) during the year prior to the addition of the research nurse and 50% (126/253) after the addition (P < 0.001). Refusal rates were 21% (22/106) when recruitment was carried out by the nurse and 15% (13/86) when done by physicians (P = 0.41). Review of records to identify eligible study patients showed agreement between the study nurse and physician on 78/80 (97.5%) of the charts reviewed (kappa = 0.94). CONCLUSIONS:Addition of a shared research nurse increased recruitment of patients and demonstrated equivalent judgment of the research nurse and physician investigators regarding patient eligibility for the study. This arrangement demonstrates a practical and effective means of increasing the efficiency of ED-based clinical research.

journal_name

Pediatr Emerg Care

journal_title

Pediatric emergency care

authors

Isaacman DJ,Reynolds EA

doi

10.1097/00006565-199610000-00004

subject

Has Abstract

pub_date

1996-10-01 00:00:00

pages

340-2

issue

5

eissn

0749-5161

issn

1535-1815

journal_volume

12

pub_type

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