Gastrointestinal transit of amoxicillin modified-release tablets and a placebo tablet including pharmacokinetic assessments of amoxicillin.

abstract：:We investigated the action of the new aminosalicylate olsalazine (disodium azodisalicylate) on arachidonic acid metabolism in comparison with 5-aminosalicylic acid (5-ASA) and sulphasalazine (SASP) by in vitro incubation of cellular homogenates from human polymorphonuclear (PMNL) and mononuclear (MNL) leukocytes with ...

journal_title：Scandinavian journal of gastroenterology

authors： Horn H,Preclik G,Stange EF,Ditschuneit H

更新日期：1991-08-01 00:00:00

abstract：OBJECTIVE:Sofosbuvir and simeprevir in combination with standard therapy are now available for the treatment of patients chronically infected with hepatitis C virus (HCV) genotype 1. With boceprevir and telaprevir, four treatment options are, therefore, now available to clinicians. Phase 3 studies conducted with simepr...

journal_title：Scandinavian journal of gastroenterology

authors： Brochot E,Helle F,François C,Castelain S,Capron D,Nguyen-Khac E,Duverlie G

更新日期：2015-04-01 00:00:00

abstract：:Two screenings with Hemoccult-II were performed in a randomized study, allocating 30,970 persons to screening and 30,968 as controls in a population of 140,000 between 45 and 74 years old on the island of Funen, Denmark. The test was completed in 20,672 initially and in 18,779 of these during rescreening 2 years later...

journal_title：Scandinavian journal of gastroenterology

authors： Kronborg O,Fenger C,Olsen J,Bech K,Søndergaard O

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:To compare the effect of combination therapy with interferon-alpha (INF-alpha) and granulocyte-macrophage colony-stimulating factor (GM-CSF) to monotherapy with INF-alpha in patients with chronic hepatitis C infection. METHODS:Forty-five consecutive patients with chronic hepatitis C, all presenting with ele...

journal_title：Scandinavian journal of gastroenterology

authors： Grønbaek K,Krarup HB,Ring-Larsen H,Schaffalitzky de Muckadell O,Møller A,Schlichting P,Vyberg M

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:Constipation is a collective term for symptoms of different aetiologies and pathophysiologies. Our aim was to determine the prevalence of colorectal pathophysiology findings in a prospective series of patients with chronic constipation. METHODS:A total of 155 consecutive patients with chronic constipation u...

journal_title：Scandinavian journal of gastroenterology

authors： Glia A,Lindberg G,Nilsson LH,Mihocsa L,Akerlund JE

更新日期：1998-12-01 00:00:00

abstract：OBJECTIVES:Systematic screening for chronic hepatitis B and C does not yet exist in Germany. Therefore, the implementation of a screening approach within a preventive medical examination performed by primary care physicians ('Check-Up 35+') was evaluated in a recent prospective multicenter study. The present analysis e...

journal_title：Scandinavian journal of gastroenterology

authors： Barth C,Neusser S,Biermann J,Wasem J,Berg T,Wiegand J,Wolffram I,Petroff D,Aidelsburger P,Grünbauer A,Neumann A

更新日期：2018-01-01 00:00:00

abstract：:The anal sphincter thickness was measured ultrasonographically in 30 asymptomatic subjects (13 male and 17 female: 23 young and 7 old). The internal anal sphincter (IAS) was measured at its thickest portion in the anal canal, its borders lying between the submucosa and the external and sphincter (EAS). The EAS was mea...

journal_title：Scandinavian journal of gastroenterology

authors： Papachrysostomou M,Pye SD,Wild SR,Smith AN

更新日期：1993-06-01 00:00:00

abstract：:The effect of antral balloon distension on acid secretion and the plasma gastrin concentration was studied in 8 duodenal ulcer patients. Antral distension significantly increased the acid secretion to about 30% of the peak acid response to pentagastrin without any change in the plasma gastrin concentration. Antral dis...

journal_title：Scandinavian journal of gastroenterology

authors： Bergegardh S,Nilsson G,Olbe L

更新日期：1976-01-01 00:00:00

abstract：:The immunological result of infection with Hepatitis C virus (HCV) depends on the delicate balance between a vigorous immune response that may clear the infection, but with a risk of unspecific inflammation and, or a less inflammatory response that leads to chronic infection. In general, exhaustion and impairment of c...

journal_title：Scandinavian journal of gastroenterology

authors： Hartling HJ,Ballegaard VC,Nielsen NS,Gaardbo JC,Nielsen SD

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:Gastric cancer confined to the muscularis propria (mp) has a favorable prognosis, but still belongs to the advanced category. Many oncologists have difficulties in selecting treatment modalities owing to the confused situation of mp cancer. To clarify the therapeutic strategy, the clinicopathological characte...

journal_title：Scandinavian journal of gastroenterology

authors： Park SS,Kim CS,Mok YJ,Kim SJ,Kim HI

更新日期：2005-04-01 00:00:00

abstract：:OBJECTIVE. Colon capsule endoscopy (CCE) proved to be highly sensitive in detection of colorectal polyps (CP). Major limitation is the time-consuming video reading. The aim of this prospective, double-center study was to assess the theoretical time-saving potential and its possible impact on the reliability of "QuickV...

journal_title：Scandinavian journal of gastroenterology

authors： Farnbacher MJ,Krause HH,Hagel AF,Raithel M,Neurath MF,Schneider T

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Barrett esophagus (BE) is a premalignant condition resulting from chronic acid gastroesophageal reflux and is associated with increased epithelial cell proliferation. Elimination of acid reflux might decrease cancer risk by affecting cell proliferation in BE. The effect of elimination of acid reflux on epith...

journal_title：Scandinavian journal of gastroenterology

authors： Peters FT,Ganesh S,Kuipers EJ,Sluiter WJ,Karrenbeld A,de Jager-Krikken A,Klinkenberg-Knol EC,Lamers CB,Kleibeuker JH

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:Gastric ulcer healing is mediated by various endogenous growth factors. In this experimental study effect of locally and systemically applied recombinant human transforming growth factor beta 3 (rhTGF-beta 3) on gastric ulcer healing was investigated in the rat. METHODS AND RESULTS:Gastric ulcers were induc...

journal_title：Scandinavian journal of gastroenterology

authors： Coerper S,Sigloch E,Cox D,Starlinger M,Köveker G,Becker HD

更新日期：1997-10-01 00:00:00

abstract：:The median number of mast cells (with 95% confidence interval) in jejunal specimens from 79 individuals was 108 (93-121)/mm2 section area. The distribution was unimodal and slightly skewed to the right. No relation was found between mast cell number and sex, age, height, or weight. A history of possible allergic manif...

journal_title：Scandinavian journal of gastroenterology

authors： Selbekk BH,Larsen S,Stadaas J

更新日期：1985-03-01 00:00:00

abstract：:To investigate the inhibitory influence on esophageal motility of prolonged beta-2-adrenergic stimulation, esophageal peristalsis was studied in 10 volunteers. The beta-2 agonist terbutaline was given orally, 5 mg three times daily, for 10 days, and the subjects were studied before medication (basal), on days 3 and 10...

journal_title：Scandinavian journal of gastroenterology

authors： Lyrenäs E,Sand C,Abrahamsson H

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:The DNA mismatch repair gene mutations underlying hereditary non-polyposis colorectal cancer syndrome (HNPCC) also predispose, besides colorectal and endometrial cancer, to gastric cancer. usually of the intestinal type. The carcinogenetic pathway behind the elevated gastric cancer risk is largely unknown. ...

journal_title：Scandinavian journal of gastroenterology

authors： Renkonen-Sinisalo L,Sipponen P,Aarnio M,Julkunen R,Aaltonen LA,Sarna S,Järvinen HJ,Mecklin JP

更新日期：2002-05-01 00:00:00

abstract：:In a previous study we reported lack of improvement in oesophageal motor function after complete healing of oesophagitis achieved by treatment with omeprazole for a median duration of 12 weeks. This study investigates the effect on oesophageal acid exposure of a longer period of complete remission. It was decided to a...

journal_title：Scandinavian journal of gastroenterology

authors： Singh P,Taylor RH,Colin-Jones DG

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVE:The management of high-grade dysplasia (HGD) in polypoid lesions in patients with ulcerative colitis (UC) is not well characterized. The purpose of this study was to characterize the clinical course of patients with HGD in adenoma-like dysplasia-associated lesion or masses (DALMs) in the absence of any synchr...

journal_title：Scandinavian journal of gastroenterology

authors： Blonski W,Kundu R,Furth EF,Lewis J,Aberra F,Lichtenstein GR

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:Primary sclerosing cholangitis (PSC) confers a high risk of development of hepatobiliary carcinoma (HBC). The aim of the study was to identify indicators and risk factors for developing HBC in PSC patients. MATERIAL AND METHODS:Thirty-nine PSC patients with HBC at time of HBC diagnosis were compared with 101...

journal_title：Scandinavian journal of gastroenterology

authors： Tischendorf JJ,Meier PN,Strassburg CP,Klempnauer J,Hecker H,Manns MP,Krüger M

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Beneficial effects of lactobacilli have been reported in experimental colitis. On the other hand, despite the controversial role of nitric oxide (NO) in the inflammatory gut process, a protective action of exogenous NO in inflammation has been suggested. Consequently, this study aimed to determine the effect...

journal_title：Scandinavian journal of gastroenterology

authors： Lamine F,Fioramonti J,Bueno L,Nepveu F,Cauquil E,Lobysheva I,Eutamène H,Théodorou V

更新日期：2004-01-01 00:00:00

abstract：:Small-intestinal mucosal biopsy specimens obtained by a Watson capsule were assessed by light (LM) and scanning electron (SEM) microscopy in 18 patients with various sites of Crohn's disease and in 6 healthy controls. By means of LM, partial villous atrophy of the upper small-intestinal mucosa was assessed in six pati...

journal_title：Scandinavian journal of gastroenterology

authors： Nyhlin H,Stenling R

更新日期：1984-05-01 00:00:00

abstract：:Enzyme activity changes in the functioning segment (the shunt) of the small intestine during the first 6 months after by-pass operation for obesity were investigated. At the ligament of Treitz no significant changes in disaccharidase activities occurred, whereas two intracellular beta-galactosidases showed increased a...

journal_title：Scandinavian journal of gastroenterology

authors： Asp NG,Gudmand-Høyer G,Andersen B

更新日期：1979-01-01 00:00:00

abstract：:Background: Neuroendocrine tumours (NETs) in the ileum grow slowly but metastasise to the liver at an early stage. After resection of the primary tumour and mesenteric lymph nodes, selected patients with liver metastases have been operated with curative intention. Recurrence-free survival seems low, suggesting that mi...

journal_title：Scandinavian journal of gastroenterology

authors： Fossmark R,Balto TM,Martinsen TC,Grønbech JE,Munkvold B,Mjønes PG,Waldum HL

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:The aim of this investigation was to elucidate retrospectively the therapeutic effect of infliximab in patients with active Crohn's disease (CD) under nutritional therapy. MATERIAL AND METHODS:Using a review of the clinical records in 24 nationwide institutions specializing in inflammatory bowel disease, the...

journal_title：Scandinavian journal of gastroenterology

authors： Matsumoto T,Iida M,Kohgo Y,Imamura A,Kusugami K,Nakano H,Fujiyama Y,Matsu T,Hibi T

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVE:Antigliadin antibodies (AGA) show good sensitivity but low specificity for celiac disease and can also be found in healthy individuals. However, data suggest that AGA positivity might be related to distinct disease entities such as allergy and gluten ataxia. Our aim here is to explore the clinical relevance o...

journal_title：Scandinavian journal of gastroenterology

authors： Ruuskanen A,Kaukinen K,Collin P,Huhtala H,Valve R,Mäki M,Luostarinen L

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:While marked changes in the frequency of hepatobiliary malignancies, most notably hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC), have been observed in different populations, no such data have been reported for Germany. We aimed to provide epidemiological data on recent trends in liv...

journal_title：Scandinavian journal of gastroenterology

authors： von Hahn T,Ciesek S,Wegener G,Plentz RR,Weismüller TJ,Wedemeyer H,Manns MP,Greten TF,Malek NP

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:The aim of the present study was to evaluate the effect of a moderate diet restriction on the progression of preneoplastic foci into hepatocellular carcinomas (HCCs) and whether such an effect was related to altered cell proliferation, apoptosis, and/or tumour contents of lipid-soluble antioxidants. METHODS...

journal_title：Scandinavian journal of gastroenterology

authors： Wang GS,Olsson JM,Eriksson LC,Stål P

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:It has been reported that epithelial growth factor (EGF) and transforming growth factor-alpha (TGF-alpha) play an important role in colonic mucosal defense and repair. Waved-2 (wa-2) mice harboring a defect EGF-R and phenotypically similar to TGF-alpha knockout mice provide a novel approach to study the role...

journal_title：Scandinavian journal of gastroenterology

authors： Egger B,Büchler MW,Lakshmanan J,Moore P,Eysselein VE

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Our object was to study the role of non-steroidal anti-inflammatory drugs (NSAIDs) as a risk factor in upper gastrointestinal bleeding. METHODS:Forty-eight patients with acute bleeding due to esophagitis, gastric or duodenal ulcer, or erosions and 156 age- and sex-matched control patients from the same emer...

journal_title：Scandinavian journal of gastroenterology

authors： Matikainen M,Kangas E

更新日期：1996-09-01 00:00:00

abstract：OBJECTIVE:To report our endoscopic outcomes and explore the effects of duration of impaction and anesthetic methods on the endoscopic removal of foreign bodies in the upper gastrointestinal tract. METHODS:All consecutive patients with suspected foreign body (FB) ingestion between January 2013 and June 2016 were enroll...

journal_title：Scandinavian journal of gastroenterology

authors： Geng C,Li X,Luo R,Cai L,Lei X,Wang C

更新日期：2017-11-01 00:00:00