Suppressive effects of adaptive servo-ventilation on ventricular premature complexes with attenuation of sympathetic nervous activity in heart failure patients with sleep-disordered breathing.

Abstract:

:Ventricular arrhythmias play a critical role in chronic heart failure (CHF) and are associated with adverse clinical outcomes. Sleep-disordered breathing (SDB) is associated with arrhythmias and/or a poor prognosis in CHF. Adaptive servo-ventilation (ASV) is a ventilatory support system designed to normalize ventilation in CHF patients with SDB. However, the effects of ASV on ventricular arrhythmias and sympathetic nervous activity are still unclear. Nineteen CHF patients with SDB were examined. We performed simultaneous overnight polysomnography and 24-h Holter ECG monitoring, and measured levels of daily urinary catecholamines for two consecutive days (baseline and on ASV). ASV significantly improved the apnea-hypopnea index (p < 0.01), arousal index (p < 0.01), and mean SpO(2) (p < 0.01), and decreased daily urinary catecholamines (0.466-0.353 mg/day, p = 0.016) compared to baseline. Furthermore, power in the low to high frequency range as a marker of sympathetic nervous activity decreased across a 24-h period (24-h period: 2.8-1.9, p = 0.017; during daytime: 3.7-2.3, p = 0.013; and during sleep time: 1.5-1.3, p = 0.026). Importantly, ASV significantly decreased ventricular premature complexes not only during sleep time but also across a 24-h period (40.5-21.9 beats/h, p = 0.013). The short-term use of ASV reduced ventricular arrhythmias with the attenuation of sympathetic nervous activity, as demonstrated by urinary catecholamines and heart rate variability. ASV may have anti-sympathetic nervous and anti-arrhythmic effects for CHF with SDB.

journal_name

Heart Vessels

journal_title

Heart and vessels

authors

Iwaya S,Yoshihisa A,Nodera M,Owada T,Yamada S,Sato T,Suzuki S,Yamaki T,Sugimoto K,Kunii H,Nakazato K,Suzuki H,Saitoh S,Takeishi Y

doi

10.1007/s00380-013-0394-2

subject

Has Abstract

pub_date

2014-07-01 00:00:00

pages

470-7

issue

4

eissn

0910-8327

issn

1615-2573

journal_volume

29

pub_type

杂志文章
  • Effect of ectasia size or the ectasia ratio on the thrombosis in myocardial infarction frame count in patients with isolated coronary artery ectasia.

    abstract::Coronary blood flow was quantified using the thrombosis in myocardial infarction (TIMI) frame-count method. This measurement has been significantly correlated with flow velocity measured invasively by use of a Doppler flow wire. Coronary artery ectasia or aneurysm (CEA) is thought to be present in patients with a slow...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-005-0831-y

    authors: Kosar F,Acikgoz N,Sahin I,Topal E,Aksoy Y,Cehreli S

    更新日期:2005-09-01 00:00:00

  • Effect of fibrillatory wave amplitude on coronary blood flow as assessed by thrombolysis in myocardial infarction frame count in patients with atrial fibrillation.

    abstract::Atrial fibrillation (AF) is the most common arrhythmia, characterized by a lack of atrial contraction and an irregular ventricular rhythm. We assessed the effect of fibrillatory wave amplitude on coronary blood flow in patients with AF using the thrombolysis in myocardial infarction (TIMI) frame count. Sixty-one patie...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-018-1121-9

    authors: Sumimoto Y,Kurisu S,Hitta K,Ikenaga H,Ishibashi K,Fukuda Y,Nakano Y,Kihara Y

    更新日期:2018-07-01 00:00:00

  • Ibutilide protects against cardiomyocytes injury via inhibiting endoplasmic reticulum and mitochondrial stress pathways.

    abstract::Atrial fibrillation (AF) is a complex disease with multiple inter-relating causes culminating in rapid atrial activation and atrial structural remodeling. The contribution of endoplasmic reticulum and mitochondria stress to AF has been highlighted. As the class III antiarrhythmic agent, ibutilide are widely used to AF...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-016-0891-1

    authors: Wang Y,Wang YL,Huang X,Yang Y,Zhao YJ,Wei CX,Zhao M

    更新日期:2017-02-01 00:00:00

  • Impact of Killip classification on acute myocardial infarction: data from the SAIKUMA registry.

    abstract::Therapeutic devices for acute myocardial infarction (AMI) have evolved dramatically in recent years. However, the impact of the Killip classification of AMI outcomes in patients undergoing aggressive percutaneous coronary intervention remains unclear. We performed a 10-year retrospective review of 2062 patients diagno...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-017-1017-0

    authors: Taguchi E,Konami Y,Inoue M,Suzuyama H,Kodama K,Yoshida M,Miyamoto S,Nakao K,Sakamoto T

    更新日期:2017-12-01 00:00:00

  • Surgical management of a uterine leiomyoma extending through the inferior vena cava into the right heart.

    abstract::We present a case of a 38-year-old woman with intravenous leiomyomatosis originating from the uterus involving the right ventricle, right atrium, inferior vena cava, and iliac veins. Tumors in the heart and the inferior vena cava were removed using cardiopulmonary bypass and circulatory arrest; 10 days after the cardi...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s003800200049

    authors: Gaudino M,Spatuzza P,Snider F,Luciani N,Cina G,Possati G

    更新日期:2002-12-01 00:00:00

  • Changes in serum interleukin-6 and high-sensitivity C-reactive protein levels in patients with acute coronary syndrome and their responses to simvastatin.

    abstract::The role of inflammation in acute coronary syndrome (ACS) and the mechanism by which statin treats ACS is explored. Serum high-sensitivity C-reactive protein (hs-CRP) and interleukin-6 (IL-6) levels were measured in 50 patients with ACS [including 30 cases with unstable angina (UA) and 20 patients with acute myocardia...

    journal_title:Heart and vessels

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/s00380-004-0776-6

    authors: Luo Y,Jiang D,Wen D,Yang J,Li L

    更新日期:2004-11-01 00:00:00

  • Analysis of 10-year nationwide population-based data on sex differences in hospitalization for heart failure.

    abstract::Sex-related factors play an important role in the pathophysiology of heart failure (HF). However, trends in sex-related differences in hospital management for HF are not clear. We identified patients hospitalized for HF through a nationwide database (National Health Insurance in Taiwan), containing 722,272 subjects fr...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-012-0299-5

    authors: Yang HY,Chiu WC,Huang JH,Hsu CY,Lin YK,Chen YJ

    更新日期:2013-11-01 00:00:00

  • ZBTB17 loss-of-function mutation contributes to familial dilated cardiomyopathy.

    abstract::Dilated cardiomyopathy (DCM) is a common primary myocardial disease leading to congestive heart failure, arrhythmia and sudden cardiac death. Increasing studies demonstrate substantial genetic determinants for DCM. Nevertheless, DCM is of substantial genetic heterogeneity, and the genetic basis for DCM in most patient...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-017-1110-4

    authors: Sun YM,Wang J,Xu YJ,Wang XH,Yuan F,Liu H,Li RG,Zhang M,Li YJ,Shi HY,Zhao L,Qiu XB,Qu XK,Yang YQ

    更新日期:2018-07-01 00:00:00

  • Intraoperative behavior of arterial grafts in the elderly and the young: a flowmetric systematic analysis.

    abstract::Extensive arterial grafting (Art-CABG) in the elderly is still questioned due to the reduced life expectancy and the supposed higher periprocedural risk. Reports further demonstrated accelerated atherosclerosis of arterial grafts in the elderly, with hampered short-term and long-term results. We reviewed our experienc...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-008-1055-8

    authors: Onorati F,Santarpino G,Lerose MA,Impiombato B,Mastroroberto P,Renzulli A

    更新日期:2008-09-01 00:00:00

  • Association of less-contrast media with clinical factors in elective percutaneous coronary intervention.

    abstract::Since the amount of contrast media during percutaneous coronary intervention (PCI) is closely related to the exacerbation of renal function, it should be important to reduce the dose of contrast media during PCI. The purpose of this retrospective study was to evaluate the association of less-contrast media with clinic...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-019-01473-3

    authors: Mukai Y,Sakakura K,Yamamoto K,Taniguchi Y,Tsukui T,Seguchi M,Wada H,Momomura SI,Fujita H

    更新日期:2020-02-01 00:00:00

  • Soluble urokinase-type plasminogen activator receptor represents exercise tolerance and predicts adverse cardiac events in patients with heart failure.

    abstract::Soluble urokinase-type plasminogen activator receptor (suPAR) is a membrane-binding protein that is released into the blood stream by immune activation. Recent reports suggest that circulating suPAR levels are associated with adverse cardiovascular outcomes. Exercise tolerance is an independent predictor of prognosis ...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-019-01538-3

    authors: Ishikawa H,Izumiya Y,Shibata A,Ichikawa Y,Yamaguchi T,Yamaguchi Y,Kitada R,Iwata S,Ehara S,Tomita S,Hanatani A,Yoshiyama M

    更新日期:2020-05-01 00:00:00

  • Axillo-femoral bypass steal due to subclavian artery stenosis.

    abstract::Subclavian artery stenosis can cause a flow reversal-so-called steal-not only in the ipsilateral vertebral artery, but also in the internal mammary artery in patients with a history of coronary-artery bypass grafting. Subclavian artery stenosis is also associated with peripheral artery disease elsewhere. We report a n...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-016-0821-2

    authors: Shigyo H,Kawarada O,Noguchi T,Ogawa H,Yasuda S

    更新日期:2016-11-01 00:00:00

  • Difference in epicardial adipose tissue distribution between paroxysmal atrial fibrillation and coronary artery disease.

    abstract:BACKGROUND:An increase in epicardial adipose tissue (EAT) volume is associated with the development of atrial fibrillation (AF) and coronary artery disease (CAD), but little is known about differences in its distribution. METHODS AND RESULTS:We included 50 patients with paroxysmal AF (PAF), 50 patients with CAD, and 5...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-020-01575-3

    authors: Hasebe H,Yoshida K,Nogami A,Ieda M

    更新日期:2020-08-01 00:00:00

  • Transient endothelial dysfunction following flow-mediated dilation assessment.

    abstract::Flow-mediated dilation (FMD) is a widely used tool to investigate endothelial function. However, FMD assessment may cause mechanical damage to the arterial endothelium. In this study we investigated the effect of FMD assessment on endothelial function. We studied 20 healthy subjects (26 ± 6 years; 12 males). FMD was a...

    journal_title:Heart and vessels

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00380-010-0087-z

    authors: Nerla R,Di Monaco A,Sestito A,Lamendola P,Di Stasio E,Romitelli F,Lanza GA,Crea F

    更新日期:2011-09-01 00:00:00

  • Reverse translational analysis of clinically reported, lamotrigine-induced cardiovascular adverse events using the halothane-anesthetized dogs.

    abstract::Lamotrigine has been used for patients with epilepsy and/or bipolar disorder, overdose of which induced the hypotension, elevation of the atrial pacing threshold, cardiac conduction delay, wide complex tachycardia, cardiac arrest and Brugada-like electrocardiographic pattern. To clarify how lamotrigine induces those c...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-020-01716-8

    authors: Goto A,Hagiwara-Nagasawa M,Kambayashi R,Nunoi Y,Izumi-Nakaseko H,Kawai S,Takei Y,Matsumoto A,Sugiyama A

    更新日期:2020-11-02 00:00:00

  • Body mass index is associated with prognosis in Japanese elderly patients with atrial fibrillation: an observational study from the outpatient clinic.

    abstract::The relationship between body mass index (BMI) and the prognosis of elderly patients with atrial fibrillation (AF) is unknown. We aimed to examine the association of body weight with the clinical outcomes among Japanese elderly patients with a history of documented AF. This observational study of AF patients from an o...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-015-0765-y

    authors: Yanagisawa S,Inden Y,Yoshida N,Kato H,Miyoshi-Fujii A,Mizutani Y,Ito T,Kamikubo Y,Kanzaki Y,Hirai M,Murohara T

    更新日期:2016-09-01 00:00:00

  • Simultaneous echocardiographic evaluation of coronary flow velocity reserve and aortic distensibility indices in hypertension.

    abstract::The coronary flow velocity reserve (CFVR), a measure of endothelial function in coronary circulation, can be measured semi-invasively in the left anterior descending coronary artery by using stress transesophageal echocardiography (TEE). During the same stress TEE, aortic distensibility indices (elastic modulus [E(p)]...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-006-0939-8

    authors: Nemes A,Forster T,Csanády M

    更新日期:2007-03-01 00:00:00

  • Changes in coagulation and fibrinolytic parameters caused by extracorporeal circulation.

    abstract::During cardiopulmonary bypass (CPB) mechanical stress and the contact of blood with artificial surfaces lead to the activation of pro- and anticoagulant systems and the complement cascade, and to changes in cellular components. This phenomenon causes the "postperfusion-syndrome", with leukocytosis, increased capillary...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/BF01747190

    authors: Grossmann R,Babin-Ebell J,Misoph M,Schwender S,Neukam K,Hickethier T,Elert O,Keller F

    更新日期:1996-01-01 00:00:00

  • The synergistic therapeutic effect of hepatocyte growth factor and granulocyte colony-stimulating factor on pulmonary hypertension in rats.

    abstract::Pulmonary arterial hypertension (PAH) is characterized by a progressive increase in pulmonary arterial pressure and vascular resistance. Despite advances in therapy for PAH, its treatment and prognosis remain poor. We aimed to investigate whether the transplantation of bone marrow mesenchymal stem cells (MSCs) overexp...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-013-0395-1

    authors: Guo Y,Su L,Li Y,Guo N,Xie L,Zhang D,Zhang X,Li H,Zhang G,Wang Y,Liu C

    更新日期:2014-07-01 00:00:00

  • Fractional flow reserve-guided percutaneous coronary intervention for an intermediate stenosis complicated by a coronary-to-pulmonary artery fistula.

    abstract::A 65-year-old man was referred to our hospital following repetitive chest pain. Invasive coronary angiography showed an intermediate stenosis of the proximal left anterior descending artery (LAD), and a coronary fistula originating distal to the stenosis draining into the main pulmonary artery. To evaluate the functio...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-015-0641-9

    authors: Ito T,Murai S,Fujita H,Tani T,Ohte N

    更新日期:2016-05-01 00:00:00

  • Low serum eicosapentaenoic acid level is a risk for ventricular arrhythmia in patients with acute myocardial infarction: a possible link to J-waves.

    abstract::Eicosapentaenoic acid (EPA) has antiarrhythmic effects. The J-wave on an electrocardiogram is associated with a high incidence of ventricular tachycardia/fibrillation (VT/VF). We evaluated relationships between EPA and J-waves, and their involvement in the occurrence of VT/VF in acute myocardial infarction (AMI). Two ...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-013-0435-x

    authors: Endo T,Tomita H,Higuma T,Abe N,Kushibiki M,Saitoh S,Yamada M,Yokota T,Echizen T,Yokoyama H,Tateyama S,Suzuki A,Ishida Y,Murakami K,Osanai T,Okumura K

    更新日期:2014-11-01 00:00:00

  • Improved left and right ventricular functions with trimetazidine in patients with heart failure: a tissue Doppler study.

    abstract::Downregulation of glucose and fatty acid oxidation occurs in heart failure (HF). Trimetazidine reduces fatty acid oxidation and increases glucose oxidation. In this single-blind study, trimetazidine, 20 mg three times per day (n = 51) or placebo (n = 36) was added to treatment of 87 HF patients receiving optimal HF th...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-008-1118-x

    authors: Gunes Y,Guntekin U,Tuncer M,Sahin M

    更新日期:2009-07-01 00:00:00

  • Hyperthermia by bathing in a hot spring improves cardiovascular functions and reduces the production of inflammatory cytokines in patients with chronic heart failure.

    abstract::Balneotherapy has been shown to reduce systemic blood pressure in healthy volunteers. Hyperthermia might ameliorate the inflammatory status in heart failure through improving cardiac function. The purpose of this study was to examine the beneficial effects of balneotherapy in patients with chronic heart failure (CHF)....

    journal_title:Heart and vessels

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00380-011-0220-7

    authors: Oyama J,Kudo Y,Maeda T,Node K,Makino N

    更新日期:2013-03-01 00:00:00

  • Altered myocardial acetylcholine and norepinephrine concentrations in right ventricular hypertrophy and failure.

    abstract::The progression of cardiac hypertrophy and failure is associated with marked changes in cardiac autonomic innervation, and there are sympathetic-parasympathetic interactions in the regulation of cardiac function. Although the indexes of sympathetic innervation have been found to be depressed with the development of he...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/BF02058280

    authors: Yamada Y,Okumura K,Hashimoto H,Ito T,Satake T

    更新日期:1991-01-01 00:00:00

  • Parameters of arterial function and structure in adult patients after coarctation repair.

    abstract::Regardless of a successful operation, patients with coarctation of aorta (CoAo) are exposed to the risk of hypertension and a propensity to vascular and end-organ damage. The aim of this study is to evaluate the influence of residual aorta stenosis as well as the age at the operation on the parameters of arterial func...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-010-0063-7

    authors: Trojnarska O,Mizia-Stec K,Gabriel M,Szczepaniak-Chicheł L,Katarzyńska-Szymańska A,Grajek S,Tykarski A,Gąsior Z,Kramer L

    更新日期:2011-07-01 00:00:00

  • Expression of vascular endothelial growth factor in human myocardial infarction.

    abstract::To define mechanisms that may influence collateral circulation and angiogenesis, we investigated vascular endothelial growth factor (VEGF) mRNA expression in human hearts. In non-ischemic human hearts, VEGF mRNA was not detected in vessels, but was found in cardiomyocytes. In hearts with myocardial infarction, the int...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/BF01745169

    authors: Shinohara K,Shinohara T,Mochizuki N,Mochizuki Y,Sawa H,Kohya T,Fujita M,Fujioka Y,Kitabatake A,Nagashima K

    更新日期:1996-01-01 00:00:00

  • Efficacy and safety of novel epicardial circumferential left atrial ablation with pulmonary vein isolation in sustained atrial fibrillation.

    abstract::The aim of this study was to examine the efficacy and safety of this novel epicardial circumferential left atrial ablation (CLAA) with pulmonary vein isolation (PVI) in sustained atrial fibrillation (AF). Thirty domestic pigs were divided equally into 3 groups: AF without ablation (AF group), AF with PVI (PVI group), ...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-014-0594-4

    authors: Jiang Z,Yin H,He Y,Ma N,Tang M,Liu H,Ding F,Mei J

    更新日期:2015-09-01 00:00:00

  • Effects of cobalt-60 gamma-radiation on the synthesis of adrenomedullin and endothelin in rat vascular smooth muscle cells.

    abstract::We studied the effects of cobalt-60 Gamma-radiation on the gene expression and secretion of adrenomedullin (Adm) and endothelin (ET) in cultured rat vascular smooth muscle cells (VSMCs). Rat VSMCs cultured in Dulbecoo's modified Eagle's medium containing 10% FBS were radiated with cobalt-60 Gamma-radiation at doses of...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-003-0709-9

    authors: Zhong G,Chen F,Bu D,Li J,Qi Y,Niu D,Wang S,Pang Y,Tang C

    更新日期:2003-09-01 00:00:00

  • Persistent symptomatic pleural effusion following coronary bypass surgery: clinical and histologic features, and treatment.

    abstract::Pleural effusions following coronary artery bypass grafting (CABG) have been reported in 65%-89% of the cases. The majority of pleural effusions are left-sided, of little significance, and resolve spontaneously. However, a few pleural effusions require specific therapeutics. We report clinical and pleural histologic f...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-006-0930-4

    authors: Charniot JC,Zerhouni K,Kambouchner M,Martinod E,Vignat N,Azorin J,Gandjbakhch I,Artigou JY

    更新日期:2007-01-01 00:00:00

  • Increased C-reactive protein is associated with future development of diabetes mellitus in essential hypertensive patients.

    abstract::Coexistence of hypertension and diabetes mellitus (DM) increases the risk of cardiovascular disease. However, factors associated with future development of DM have not been well elucidated in patients already having essential hypertension. This study prospectively included 168 patients (mean age 41 +/- 7 years, 112 me...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-009-1218-2

    authors: Weng CM,Chou CH,Huang YY,Lin CC,Liu YW,Tsai WC

    更新日期:2010-09-01 00:00:00