Effect of aging and acetyl-L-carnitine on the lipid composition of rat plasma and erythrocytes.

abstract：:A family of short interspersed repetitive elements (SINEs), designated mermaid, is present in the genomes of fish, amphibian and primates, but absent in the mouse genome. We have demonstrated that the sequences of the mermaid family are highly polymorphic in the zebrafish genome as in the human genome. We have also sh...

journal_title：Biochemical and biophysical research communications

authors： Shimoda N,Chevrette M,Ekker M,Kikuchi Y,Hotta Y,Okamoto H

更新日期：1996-03-07 00:00:00

abstract：:Hypoxia and the androgen receptor (AR) play important roles in the development and progression of prostate cancer. In this study, the combined effects of dihydrotestosterone (DHT) and hypoxia on AR-mediated transactivation were investigated. Hypoxia alone did not induce a detectable ARE-mediated response in the absenc...

journal_title：Biochemical and biophysical research communications

authors： Park C,Kim Y,Shim M,Lee Y

更新日期：2012-02-10 00:00:00

abstract：:We have previously observed that extracellular Mg2+ influences the phosphofructokinase (PFK) activity of intact Ehrlich Ascites tumour cells (EATC). In this study we have investigated the mechanism by which Mg2+ modulates this key glycolytic enzyme in EATC made permeable to the cation by either digitonin or dextran su...

journal_title：Biochemical and biophysical research communications

authors： Wolf FI,Bossi D,Cittadini A

更新日期：1991-09-16 00:00:00

abstract：:Although mTOR (mammalian target of rapamycin) activation is frequently observed in acute myeloid leukemia (AML) patients, the precise function and the downstream targets of mTOR are poorly understood. Here we revealed that PFKFB3, but not PFKFB1, PFKFB2 nor PFKFB4 was a novel downstream substrate of mTOR signaling pat...

journal_title：Biochemical and biophysical research communications

authors： Feng Y,Wu L

更新日期：2017-02-05 00:00:00

abstract：:The intrapancreatic neuropeptide galanin has been demonstrated to lower plasma insulin levels in vivo. The effects of this peptide on insulin secretion, cytoplasmic free Ca2+ concentration and membrane potential have now been studied in vitro. Glucose-stimulated insulin secretion was inhibited by galanin under these c...

journal_title：Biochemical and biophysical research communications

authors： Ahrén B,Arkhammar P,Berggren PO,Nilsson T

更新日期：1986-11-14 00:00:00

abstract：:The cyclic pyrimidine nucleotide, cCMP, is an endogenous substance in mammalian cells but little is known on its functional role. We studied the effects of cCMP, its cell-permeant analogue, N4,2'-O-dibutyryl cytidine 3':5'-cyclic monophosphate (Bt2cCMP), and of butyrate on superoxide (O2-) formation and cytosolic Ca2+...

journal_title：Biochemical and biophysical research communications

authors： Ervens J,Seifert R

更新日期：1991-01-15 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is a cancer arising from the nasopharynx epithelium. Long non-coding RNAs (lnc RNA) play a critical role in various biological processes such as cell growth, embryonic development, and tumorigenesis. In the study, for the first time, we discovered that lnc RNA taurine upregulated gene 1 ...

journal_title：Biochemical and biophysical research communications

authors： Qian W,Ren Z,Lu X

更新日期：2019-01-29 00:00:00

abstract：:The dodecapeptide MCLV3 is a functional peptide, derived from the CLV3 precursor protein, which is a candidate ligand of the CLV1/CLV2 receptor complex that restricts the stem cell population in the shoot apical meristem (SAM). MCLV3 can induce shoot and root meristem consumption, the typical phenotype of transgenic p...

journal_title：Biochemical and biophysical research communications

authors： Kondo T,Nakamura T,Yokomine K,Sakagami Y

更新日期：2008-12-05 00:00:00

abstract：:The perchloric acid-soluble protein (PSP) is an endoribonuclease and on the basis of sequence similarity has been assigned to the YjgF/YER057c/UK114 family. These family members are ubiquitous and highly conserved in evolution, and participate in regulating basic cellular metabolism. Here we present the 2.1A crystal s...

journal_title：Biochemical and biophysical research communications

authors： Zhang HM,Gao Y,Li M,Chang WR

更新日期：2010-06-18 00:00:00

abstract：:The first life forms evolved in a highly reducing environment. This reduced state is still carried by cells today, which makes the concept of "reductive stress" somewhat redundant. When oxygen became abundant on the Earth, due to the evolution of photosynthesis, life forms had to adapt or become extinct. Living organi...

journal_title：Biochemical and biophysical research communications

authors： Gutteridge JMC,Halliwell B

更新日期：2018-07-12 00:00:00

abstract：:Differences in insulin-like growth factor binding proteins (IGFBPs) expressed within estrogen receptor positive (ER+, MCF-7/6) and negative (ER-, MDA-MB-231) human breast cancer cells cultured in chemically defined medium were observed. In the absence of insulin, 17 beta-estradiol affects this expression in ER+ cells ...

journal_title：Biochemical and biophysical research communications

authors： Dubois V,Couissi D,Schonne E,Schneider YJ,Remacle C,Trouet A

更新日期：1993-04-15 00:00:00

abstract：:Bolus intravenous injection of arachidonic acid (10 mg/kg) in the rat led to the appearance of hepoxilin A3 in the circulation. The product was assayed as the Me t-BDMSi derivative of its stable trihydroxy product trioxilin A3, by capillary gas chromatography-electron impact mass spectrometry using the stable deuteriu...

journal_title：Biochemical and biophysical research communications

authors： Pace-Asciak CR,Lee SP,Martin JM

更新日期：1987-09-30 00:00:00

abstract：:Inflammatory bowel diseases, including ulcerative colitis and Crohn's disease, are persistent disorders that lead to development of colitis-associated cancer (CAC). Facilitated resolution of colitis has been addressed as a novel therapeutic strategy to control development of CAC. Resolvin D1 (RvD1) is an endogenous li...

journal_title：Biochemical and biophysical research communications

authors： Zhong X,Lee HN,Surh YJ

更新日期：2018-02-05 00:00:00

abstract：:We have previously reported that the two components of R2TP complex, RNA polymerase II-associated protein 3 (RPAP3), and Reptin, regulate apoptosis. Here we characterize another component of the complex, PIH1 domain containing protein 1 (PIH1D1). PIH1D1 interacts with both RPAP3 and Monad in HEK293 or U2OS cells. PIH1...

journal_title：Biochemical and biophysical research communications

authors： Inoue M,Saeki M,Egusa H,Niwa H,Kamisaki Y

更新日期：2010-12-17 00:00:00

abstract：:Release of soluble growth hormone binding protein (GHBP) corresponding to the extracellular domain of the GH receptor (GHR) occurs via distinct mechanisms depending on species. In human, proteolysis of full length GHR results in liberation of GHBP into the extracellular medium. A putative protease responsive for GHR c...

journal_title：Biochemical and biophysical research communications

authors： Conte F,Salles JP,Raynal P,Fernandez L,Molinas C,Tauber M,Bieth E

更新日期：2002-01-18 00:00:00

abstract：:Autophosphorylation of CaM-kinase II produces a form of the enzyme not requiring Ca(2+)/calmodulin for sustained activity. We report that autophosphorylated CaM-kinase II dephosphorylates itself in the presence of ADP (termed autodephosphorylation). The dephosphorylation was unaffected by phosphatase inhibitors and wa...

journal_title：Biochemical and biophysical research communications

authors： Kim SA,Hudmon A,Volmer A,Waxham MN

更新日期：2001-04-06 00:00:00

abstract：:Northern hybridization studies showed that the level of ovalbumin mRNA decreases in the oviduct of the Japanese quail after adulthood. In order to find out if this is due to changes in the conformation of the chromatin containing the promoter region of the gene, nuclei of the oviduct of young, adult and old birds were...

journal_title：Biochemical and biophysical research communications

authors： Upadhyay R,Gupta S,Kanungo MS

更新日期：1996-09-13 00:00:00

abstract：:Most fish protamines contain two phosphorylatable sites both of which incorporate phosphate in vivo. Here we show that in two protamines (salmine A1 and clupeine Y1) the site more distant from the N-terminus (residues 20-21) is unaffected by cAMP-dependent protein kinase while it represents the main target for protein...

journal_title：Biochemical and biophysical research communications

authors： Ferrari S,Pinna LA

更新日期：1987-05-14 00:00:00

abstract：:Attachment of leukocytes to the vascular endothelium and the subsequent migration of cells into the vessel wall are early events in atherogenesis. This process requires the expression of endothelial adhesion molecules. Since tea catechins are reputed to promote antiatherogenic activities, we investigated the effects o...

journal_title：Biochemical and biophysical research communications

authors： Ludwig A,Lorenz M,Grimbo N,Steinle F,Meiners S,Bartsch C,Stangl K,Baumann G,Stangl V

更新日期：2004-04-09 00:00:00

abstract：:Emerging evidences suggest that transcription-independent mechanism of p53 appears to make an important contribution to the overall p53-dependent apoptosis. Recently, it has been postulated that the DNA-binding domain of p53 can interact with Bcl-Xl, and subsequently the proposed molecular interaction has been shown b...

journal_title：Biochemical and biophysical research communications

authors： Xu H,Tai J,Ye H,Kang CB,Yoon HS

更新日期：2006-03-24 00:00:00

abstract：:The ability to simultaneously isolate intact DNA-free RNA, genomic DNA, and proteins from a biological specimen can be useful in cloning genes and analyzing gene expression. Equilibrium density gradient centrifugation with CsCl is a useful tool for fractionating, quantitatively separating, and characterizing RNA, DNA,...

journal_title：Biochemical and biophysical research communications

authors： Zhang H,Chen HT,Glisin V

更新日期：2003-12-05 00:00:00

abstract：:A Bacillus thuringiensis isolate, 89-T-34-22, belonging to the serovar shandongiensis (H22) produced noninsecticidal and nonhemolytic proteins crystallizing into irregular-shaped parasporal inclusions. The proteins showed in vitro cytotoxicity to human cells, including cancer cells, only when activated by protease tre...

journal_title：Biochemical and biophysical research communications

authors： Lee DW,Akao T,Yamashita S,Katayama H,Maeda M,Saitoh H,Mizuki E,Ohba M

更新日期：2000-05-27 00:00:00

abstract：:Tissue factor (TF) is an initiation factor for blood coagulation and its expression is induced on endothelial cells during inflammatory or immune responses. We designed an antisense oligodeoxynucleotide (AS-1/TF) for rat TF and studied its effect on hepatic ischemic reperfusion injury. AS-1/TF was delivered intravenou...

journal_title：Biochemical and biophysical research communications

authors： Nakamura K,Kadotani Y,Ushigome H,Akioka K,Okamoto M,Ohmori Y,Yaoi T,Fushiki S,Yoshimura R,Yoshimura N

更新日期：2002-09-27 00:00:00

abstract：:Collagens are the most abundant structural proteins found in the extracellular matrix of vertebrates. Knowledge of the mechanical behavior of collagen monomers is essential for understanding the mechanical properties of collagen fibrils that constitute the main architectural framework of skin, bone, cartilage, and oth...

journal_title：Biochemical and biophysical research communications

authors： Sun YL,Luo ZP,Fertala A,An KN

更新日期：2002-07-12 00:00:00

abstract：:MicroRNA (miRNA)-mediated gene silencing has recently emerged as a major mechanism of gene expression regulation during development in a variety of species. Little is known, however, about the presence of components of miRNA machinery in mammalian organogenesis. In this study, we report that members of the Argonaute (...

journal_title：Biochemical and biophysical research communications

authors： Lü J,Qian J,Chen F,Tang X,Li C,Cardoso WV

更新日期：2005-08-26 00:00:00

abstract：:The asymmetric transbilayer distribution of phospholipids in the plasma membrane and the regulation of phosphatidylserine (PS) exposure at the cell surface of animal cells are of high physiological significance. It has been shown previously that annexin V is one of the most sensitive tools with which the presence of s...

journal_title：Biochemical and biophysical research communications

authors： Geldwerth D,Helley D,de Jong K,Sabolovic' D,Sestier C,Roger J,Pons JN,Freyssinet JM,Devaux PF,Kuypers FA

更新日期：1999-04-29 00:00:00

abstract：:In this paper, based on the approach by combining the "functional domain composition" [K.C. Chou, Y. D. Cai, J. Biol. Chem. 277 (2002) 45765] and the pseudo-amino acid composition [K.C. Chou, Proteins Struct. Funct. Genet. 43 (2001) 246; Correction Proteins Struct. Funct. Genet. 2044 (2001) 2060], the Nearest Neighbou...

journal_title：Biochemical and biophysical research communications

authors： Cai YD,Chou KC

更新日期：2003-05-30 00:00:00

abstract：:Stromal cell-derived factor 1 (SDF-1) regulates neovascularization, which is coordinately controlled by endothelial cells (EC) and their surrounding cells, pericytes or smooth muscle cells. In the basal state, SDF-1 expression is much lower in EC than in their surrounding cells. In this study, we evaluated epigenetic ...

journal_title：Biochemical and biophysical research communications

authors： Seo J,Kim YO,Jo I

更新日期：2009-05-08 00:00:00

abstract：:A novel photoaffinity label, 8-N(3)-3'-biotinyl-ATP, has been synthesized. The introduction of an additional biotin residue is advantageous for easy detection of labeled proteins. This could be first tested by reaction with the F(1)-ATPase from the thermophilic bacterium PS3 (TF(1)). UV irradiation of TF(1) in the pre...

journal_title：Biochemical and biophysical research communications

authors： Schäfer HJ,Coskun U,Eger O,Godovac-Zimmermann J,Wieczorek H,Kagawa Y,Grüber G

更新日期：2001-09-07 00:00:00

abstract：:Smad2 is a crucial component of intracellular signaling by transforming growth factor-β (TGFβ). Here we describe that Smad2 is glycosylated, which is a novel for Smad2 post-translational modification. We showed that the Smad2 glycosylation was inhibited upon treatment of cells with 17β-estradiol, and was enhanced in c...

journal_title：Biochemical and biophysical research communications

authors： Gotoh T,Iwahana H,Kannan S,Marei RG,Mousa H,Elgamal M,Souchelnytskyi S

更新日期：2020-01-22 00:00:00